Details for: Atp1a1
Associated with
Other Information
Genular Protein ID: 3437470825
Symbol: AT1A1_RAT
Name: Sodium/potassium-transporting ATPase subunit alpha-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3028470
Title: Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain.
PubMed ID: 3028470
DOI: 10.1021/bi00373a001
PubMed ID: 2822682
Title: Primary structures of two types of alpha-subunit of rat brain Na+,K+,-ATPase deduced from cDNA sequences.
PubMed ID: 2822682
PubMed ID: 2822726
Title: Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.
PubMed ID: 2822726
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2994074
Title: Molecular cloning of rat brain Na,K-ATPase alpha-subunit cDNA.
PubMed ID: 2994074
PubMed ID: 2166579
Title: Cloning and analysis of the 5'-flanking region of rat Na+/K(+)-ATPase alpha 1 subunit gene.
PubMed ID: 2166579
PubMed ID: 7510709
Title: Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.
PubMed ID: 7510709
PubMed ID: 9435504
Title: Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
PubMed ID: 9435504
PubMed ID: 10473631
Title: Insulin-induced stimulation of Na+,K(+)-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10.
PubMed ID: 10473631
PubMed ID: 7775468
Title: Structural basis for species-specific differences in the phosphorylation of Na,K-ATPase by protein kinase C.
PubMed ID: 7775468
PubMed ID: 10823893
Title: Phosphoinositide-3 kinase binds to a proline-rich motif in the Na+, K+-ATPase alpha subunit and regulates its trafficking.
PubMed ID: 10823893
PubMed ID: 15743908
Title: FXYD3 (Mat-8), a new regulator of Na,K-ATPase.
PubMed ID: 15743908
PubMed ID: 17283221
Title: The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase.
PubMed ID: 17283221
PubMed ID: 17939993
Title: SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process.
PubMed ID: 17939993
PubMed ID: 19339511
Title: FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C.
PubMed ID: 19339511
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 23532852
Title: A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle.
PubMed ID: 23532852
PubMed ID: 29499166
Title: Mutations in ATP1A1 Cause Dominant Charcot-Marie-Tooth Type 2.
PubMed ID: 29499166
PubMed ID: 30388404
Title: Germline de novo mutations in ATP1A1 cause renal hypomagnesemia, refractory seizures, and intellectual disability.
PubMed ID: 30388404
PubMed ID: 16914892
Title: An extracellular loop of the human non-gastric H,K-ATPase alpha-subunit is involved in apical plasma membrane polarization.
PubMed ID: 16914892
DOI: 10.1159/000095169
PubMed ID: 12730684
Title: ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase.
PubMed ID: 12730684
DOI: 10.1038/nsb924
Sequence Information:
- Length: 1023
- Mass: 113054
- Checksum: 85E98233EE6C18E9
- Sequence:
MGKGVGRDKY EPAAVSEHGD KKSKKAKKER DMDELKKEVS MDDHKLSLDE LHRKYGTDLS RGLTPARAAE ILARDGPNAL TPPPTTPEWV KFCRQLFGGF SMLLWIGAIL CFLAYGIRSA TEEEPPNDDL YLGVVLSAVV IITGCFSYYQ EAKSSKIMES FKNMVPQQAL VIRNGEKMSI NAEDVVVGDL VEVKGGDRIP ADLRIISANG CKVDNSSLTG ESEPQTRSPD FTNENPLETR NIAFFSTNCV EGTARGIVVY TGDRTVMGRI ATLASGLEGG QTPIAEEIEH FIHLITGVAV FLGVSFFILS LILEYTWLEA VIFLIGIIVA NVPEGLLATV TVCLTLTAKR MARKNCLVKN LEAVETLGST STICSDKTGT LTQNRMTVAH MWFDNQIHEA DTTENQSGVS FDKTSATWFA LSRIAGLCNR AVFQANQENL PILKRAVAGD ASESALLKCI EVCCGSVMEM REKYTKIVEI PFNSTNKYQL SIHKNPNASE PKHLLVMKGA PERILDRCSS ILLHGKEQPL DEELKDAFQN AYLELGGLGE RVLGFCHLLL PDEQFPEGFQ FDTDEVNFPV DNLCFVGLIS MIDPPRAAVP DAVGKCRSAG IKVIMVTGDH PITAKAIAKG VGIISEGNET VEDIAARLNI PVNQVNPRDA KACVVHGSDL KDMTSEELDD ILRYHTEIVF ARTSPQQKLI IVEGCQRQGA IVAVTGDGVN DSPALKKADI GVAMGIVGSD VSKQAADMIL LDDNFASIVT GVEEGRLIFD NLKKSIAYTL TSNIPEITPF LIFIIANIPL PLGTVTILCI DLGTDMVPAI SLAYEQAESD IMKRQPRNPK TDKLVNERLI SMAYGQIGMI QALGGFFTYF VILAENGFLP FHLLGIRETW DDRWINDVED SYGQQWTYEQ RKIVEFTCHT AFFVSIVVVQ WADLVICKTR RNSVFQQGMK NKILIFGLFE ETALAAFLSY CPGMGAALRM YPLKPTWWFC AFPYSLLIFV YDEVRKLIIR RRPGGWVEKE TYY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.