Genular: Defining Cellular Identity and Function

Details for: Atp1a2

Gene ID: 24212

Symbol: Atp1a2

Ensembl ID: ENSRNOG00000007290

Description: ATPase Na+/K+ transporting subunit alpha 2

Associated with

Cardiac conduction
(R-RNO-5576891)
Ion channel transport
(R-RNO-983712)
Ion homeostasis
(R-RNO-5578775)
Ion transport by p-type atpases
(R-RNO-936837)
Muscle contraction
(R-RNO-397014)
Transport of small molecules
(R-RNO-382551)
Adult locomotory behavior
(GO:0008344)
Amygdala development
(GO:0021764)
Atpase-coupled monoatomic cation transmembrane transporter activity
(GO:0019829)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Atp metabolic process
(GO:0046034)
Behavioral fear response
(GO:0001662)
Cardiac muscle contraction
(GO:0060048)
Caveola
(GO:0005901)
Cell projection
(GO:0042995)
Cell surface
(GO:0009986)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to steroid hormone stimulus
(GO:0071383)
Cytoplasm
(GO:0005737)
Dendritic spine
(GO:0043197)
Endosome
(GO:0005768)
Energy coupled proton transmembrane transport, against electrochemical gradient
(GO:0015988)
Establishment or maintenance of transmembrane electrochemical gradient
(GO:0010248)
Intercalated disc
(GO:0014704)
Intracellular potassium ion homeostasis
(GO:0030007)
Intracellular sodium ion homeostasis
(GO:0006883)
Locomotion
(GO:0040011)
Locomotory exploration behavior
(GO:0035641)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monoatomic cation transmembrane transport
(GO:0098655)
Negative regulation of calcium ion transmembrane transport
(GO:1903170)
Negative regulation of cytosolic calcium ion concentration
(GO:0051481)
Negative regulation of heart contraction
(GO:0045822)
Negative regulation of striated muscle contraction
(GO:0045988)
Neuronal cell body
(GO:0043025)
Neurotransmitter uptake
(GO:0001504)
Olfactory cortex development
(GO:0021989)
Organelle membrane
(GO:0031090)
P-type potassium transmembrane transporter activity
(GO:0008556)
P-type sodium:potassium-exchanging transporter activity
(GO:0005391)
Plasma membrane
(GO:0005886)
Potassium ion binding
(GO:0030955)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Protein-containing complex
(GO:0032991)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Proton transmembrane transport
(GO:1902600)
Regulation of blood pressure
(GO:0008217)
Regulation of cardiac muscle cell contraction
(GO:0086004)
Regulation of cardiac muscle contraction by calcium ion signaling
(GO:0010882)
Regulation of muscle contraction
(GO:0006937)
Regulation of respiratory gaseous exchange by nervous system process
(GO:0002087)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of striated muscle contraction
(GO:0006942)
Regulation of the force of heart contraction
(GO:0002026)
Regulation of vasoconstriction
(GO:0019229)
Relaxation of cardiac muscle
(GO:0055119)
Response to auditory stimulus
(GO:0010996)
Response to glycoside
(GO:1903416)
Response to nicotine
(GO:0035094)
Sarcolemma
(GO:0042383)
Sodium:potassium-exchanging atpase complex
(GO:0005890)
Sodium ion binding
(GO:0031402)
Sodium ion export across plasma membrane
(GO:0036376)
Sodium ion transmembrane transport
(GO:0035725)
Sodium ion transport
(GO:0006814)
Steroid binding
(GO:0005496)
Steroid hormone binding
(GO:1990239)
T-tubule
(GO:0030315)
Visual learning
(GO:0008542)

Other Information

Proteins

Sodium/potassium-transporting ATPase subunit alpha-2

Genular Protein ID: 138620953

Symbol: AT1A2_RAT

Name: Sodium/potassium-transporting ATPase subunit alpha-2

UniProtKB Accession Codes:

P06686

Database IDs:

Citations:

PubMed ID: 3028470

Title: Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain.

PubMed ID: 3028470

DOI: 10.1021/bi00373a001

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2170235

Title: Regulation of Na+,K(+)-ATPases. I. Cloning and analysis of the 5'-flanking region of the rat NKAA2 gene encoding the alpha 2 subunit.

PubMed ID: 2170235

DOI: 10.1016/0378-1119(90)90098-c

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 23532852

Title: A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle.

PubMed ID: 23532852

DOI: 10.1074/jbc.m113.460956

Sequence Information:

Length: 1020
Mass: 112217
Checksum: 5436E795BD5B4CFA
Sequence:

MGRGAGREYS PAATTAENGG GKKKQKEKEL DELKKEVAMD DHKLSLDELG RKYQVDLSKG 
LTNQRAQDIL ARDGPNALTP PPTTPEWVKF CRQLFGGFSI LLWIGALLCF LAYGILAAME 
DEPSNDNLYL GIVLAAVVIV TGCFSYYQEA KSSKIMDSFK NMVPQQALVI REGEKMQINA 
EEVVVGDLVE VKGGDRVPAD LRIISSHGCK VDNSSLTGES EPQTRSPEFT HENPLETRNI 
CFFSTNCVEG TARGIVIATG DRTVMGRIAT LASGLEVGQT PIAMEIEHFI QLITGVAVFL 
GVSFFVLSLI LGYSWLEAVI FLIGIIVANV PEGLLATVTV CLTLTAKRMA RKNCLVKNLE 
AVETLGSTST ICSDKTGTLT QNRMTVAHMW FDNQIHEADT TEDQSGATFD KRSPTWTALS 
RIAGLCNRAV FKAGQENISV SKRDTAGDAS ESALLKCIEL SCGSVRKMRD RNPKVAEIPF 
NSTNKYQLSI HEREDSPQSH VLVMKGAPER ILDRCSTILV QGKEIPLDKE MQDAFQNAYM 
ELGGLGERVL GFCQLNLPSG KFPRGFKFDT DELNFPTEKL CFVGLMSMID PPRAAVPDAV 
GKCRSAGIKV IMVTGDHPIT AKAIAKGVGI ISEGNETVED IAARLNIPVS QVNPREAKAC 
VVHGSDLKDM TSEQLDEILR DHTEIVFART SPQQKLIIVE GCQRQGAIVA VTGDGVNDSP 
ALKKADIGIA MGISGSDVSK QAADMILLDD NFASIVTGVE EGRLIFDNLK KSIAYTLTSN 
IPEITPFLLF IIANIPLPLG TVTILCIDLG TDMVPAISLA YEAAESDIMK RQPRNSQTDK 
LVNERLISMA YGQIGMIQAL GGFFTYFVIL AENGFLPSRL LGIRLDWDDR TTNDLEDSYG 
QEWTYEQRKV VEFTCHTAFF ASIVVVQWAD LIICKTRRNS VFQQGMKNKI LIFGLLEETA 
LAAFLSYCPG MGVALRMYPL KVTWWFCAFP YSLLIFIYDE VRKLILRRYP GGWVEKETYY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp1a2

Associated with

Other Information

Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain. PubMed ID: 3028470

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Regulation of Na+,K(+)-ATPases. I. Cloning and analysis of the 5'-flanking region of the rat NKAA2 gene encoding the alpha 2 subunit. PubMed ID: 2170235