Genular: Defining Cellular Identity and Function

Details for: Avp

Gene ID: 24221

Symbol: Avp

Ensembl ID: ENSRNOG00000021229

Description: arginine vasopressin

Associated with

Aquaporin-mediated transport
(R-RNO-445717)
Cargo recognition for clathrin-mediated endocytosis
(R-RNO-8856825)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
Clathrin-mediated endocytosis
(R-RNO-8856828)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Membrane trafficking
(R-RNO-199991)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Slc-mediated transmembrane transport
(R-RNO-425407)
Transport of organic anions
(R-RNO-879518)
Transport of small molecules
(R-RNO-382551)
Transport of vitamins, nucleosides, and related molecules
(R-RNO-425397)
Vasopressin-like receptors
(R-RNO-388479)
Vasopressin regulates renal water homeostasis via aquaporins
(R-RNO-432040)
Vesicle-mediated transport
(R-RNO-5653656)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Dendrite
(GO:0030425)
Erk1 and erk2 cascade
(GO:0070371)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Grooming behavior
(GO:0007625)
Locomotory behavior
(GO:0007626)
Maternal aggressive behavior
(GO:0002125)
Maternal behavior
(GO:0042711)
Multicellular organismal-level water homeostasis
(GO:0050891)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of female receptivity
(GO:0007621)
Negative regulation of release of cytochrome c from mitochondria
(GO:0090201)
Negative regulation of transmission of nerve impulse
(GO:0051970)
Neurohypophyseal hormone activity
(GO:0005185)
Neuronal dense core vesicle
(GO:0098992)
Neuropeptide hormone activity
(GO:0005184)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cellular ph reduction
(GO:0032849)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glutamate secretion
(GO:0014049)
Positive regulation of peptidyl-serine phosphorylation
(GO:0033138)
Positive regulation of prostaglandin biosynthetic process
(GO:0031394)
Positive regulation of systemic arterial blood pressure
(GO:0003084)
Positive regulation of vasoconstriction
(GO:0045907)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein kinase c signaling
(GO:0070528)
Response to ethanol
(GO:0045471)
Response to nicotine
(GO:0035094)
Response to organic cyclic compound
(GO:0014070)
Response to testosterone
(GO:0033574)
Secretory granule
(GO:0030141)
Signal transduction
(GO:0007165)
Social behavior
(GO:0035176)
Symbiont entry into host cell
(GO:0046718)
Temperature homeostasis
(GO:0001659)
V1a vasopressin receptor binding
(GO:0031894)
V1b vasopressin receptor binding
(GO:0031895)
V2 vasopressin receptor binding
(GO:0031896)
Vasoconstriction
(GO:0042310)

Other Information

Proteins

Vasopressin-neurophysin 2-copeptin

Genular Protein ID: 1031986557

Symbol: NEU2_RAT

Name: Vasopressin-neurophysin 2-copeptin

UniProtKB Accession Codes:

P01186

Database IDs:

Citations:

PubMed ID: 1706187

Title: Rat vasopressin and oxytocin genes are linked by a long interspersed repeated DNA element (LINE): sequence and transcriptional analysis of LINE.

PubMed ID: 1706187

DOI: 10.1089/dna.1991.10.81

PubMed ID: 3768139

Title: The neurohypophyseal hormones vasopressin and oxytocin. Precursor structure, synthesis and regulation.

PubMed ID: 3768139

DOI: 10.1515/bchm3.1986.367.2.695

PubMed ID: 6315416

Title: Structural organization of the rat gene for the arginine vasopressin-neurophysin precursor.

PubMed ID: 6315416

DOI: 10.1002/j.1460-2075.1983.tb01497.x

PubMed ID: 6526016

Title: The mutant vasopressin gene from diabetes insipidus (Brattleboro) rats is transcribed but the message is not efficiently translated.

PubMed ID: 6526016

DOI: 10.1002/j.1460-2075.1984.tb02291.x

PubMed ID: 5150741

Title: Evolution of neurohypophyseal hormones: isolation of active principles from rabbits and rats.

PubMed ID: 5150741

DOI: 10.1016/s0300-9084(71)80199-2

PubMed ID: 7036996

Title: Identification of rat neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysins.

PubMed ID: 7036996

DOI: 10.1016/0006-291x(81)90493-9

PubMed ID: 891987

Title: A comparative study of partial neurophysin protein sequences of cod, guinea pig, rat and sheep.

PubMed ID: 891987

DOI: 10.1016/0014-5793(77)80478-x

PubMed ID: 6641941

Title: The glycopeptide domain of the rat vasopressin precursor.

PubMed ID: 6641941

DOI: 10.1016/0014-5793(83)80830-8

PubMed ID: 3956504

Title: Isolation and primary structure of novel neurointermediate pituitary peptides derived from the C-terminal of the rat vasopressin-neurophysin precursor (propressophysin).

PubMed ID: 3956504

DOI: 10.1111/j.1432-1033.1986.tb09558.x

Sequence Information:

Length: 168
Mass: 17923
Checksum: DB369FED09A74698
Sequence:

MLAMMLNTTL SACFLSLLAL TSACYFQNCP RGGKRATSDM ELRQCLPCGP GGKGRCFGPS 
ICCADELGCF LGTAEALRCQ EENYLPSPCQ SGQKPCGSGG RCAAAGICCS DESCVAEPEC 
REGFFRLTRA REQSNATQLD GPARELLLRL VQLAGTQESV DSAKPRVY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Avp

Associated with

Other Information

Rat vasopressin and oxytocin genes are linked by a long interspersed repeated DNA element (LINE): sequence and transcriptional analysis of LINE. PubMed ID: 1706187

The neurohypophyseal hormones vasopressin and oxytocin. Precursor structure, synthesis and regulation. PubMed ID: 3768139

Structural organization of the rat gene for the arginine vasopressin-neurophysin precursor. PubMed ID: 6315416

The mutant vasopressin gene from diabetes insipidus (Brattleboro) rats is transcribed but the message is not efficiently translated. PubMed ID: 6526016

Evolution of neurohypophyseal hormones: isolation of active principles from rabbits and rats. PubMed ID: 5150741

Identification of rat neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysins. PubMed ID: 7036996

A comparative study of partial neurophysin protein sequences of cod, guinea pig, rat and sheep. PubMed ID: 891987

The glycopeptide domain of the rat vasopressin precursor. PubMed ID: 6641941

Isolation and primary structure of novel neurointermediate pituitary peptides derived from the C-terminal of the rat vasopressin-neurophysin precursor (propressophysin). PubMed ID: 3956504