Genular: Defining Cellular Identity and Function

Details for: Tspo

Gene ID: 24230

Symbol: Tspo

Ensembl ID: ENSRNOG00000010549

Description: translocator protein

Associated with

Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroid hormones
(R-RNO-196071)
Metabolism of steroids
(R-RNO-8957322)
Pregnenolone biosynthesis
(R-RNO-196108)
Adrenal gland development
(GO:0030325)
Androgen binding
(GO:0005497)
Behavioral response to pain
(GO:0048266)
Benzodiazepine receptor activity
(GO:0008503)
Cellular hypotonic response
(GO:0071476)
Cellular response to lipopolysaccharide
(GO:0071222)
Cellular response to zinc ion
(GO:0071294)
Chloride transport
(GO:0006821)
Cholesterol binding
(GO:0015485)
Cholesterol homeostasis
(GO:0042632)
Contact inhibition
(GO:0060242)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Establishment of protein localization to mitochondrion
(GO:0072655)
Glial cell migration
(GO:0008347)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid transport
(GO:0006869)
Maintenance of protein location in mitochondrion
(GO:0072656)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Monoatomic ion transport
(GO:0006811)
Negative regulation of atp metabolic process
(GO:1903579)
Negative regulation of corticosterone secretion
(GO:2000853)
Negative regulation of glial cell proliferation
(GO:0060253)
Negative regulation of mitochondrion organization
(GO:0010823)
Negative regulation of mitophagy
(GO:1901525)
Negative regulation of nitric oxide biosynthetic process
(GO:0045019)
Negative regulation of protein ubiquitination
(GO:0031397)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Peripheral nervous system axon regeneration
(GO:0014012)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of calcium ion transport
(GO:0051928)
Positive regulation of glial cell proliferation
(GO:0060252)
Positive regulation of mitochondrial depolarization
(GO:0051901)
Positive regulation of programmed necrotic cell death
(GO:0062100)
Positive regulation of reactive oxygen species metabolic process
(GO:2000379)
Protein binding
(GO:0005515)
Regulation of steroid biosynthetic process
(GO:0050810)
Response to acetylcholine
(GO:1905144)
Response to axon injury
(GO:0048678)
Response to manganese ion
(GO:0010042)
Response to pain
(GO:0048265)
Response to progesterone
(GO:0032570)
Response to testosterone
(GO:0033574)
Response to vitamin b1
(GO:0010266)
Response to xenobiotic stimulus
(GO:0009410)
Steroid biosynthetic process
(GO:0006694)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

Translocator protein

Genular Protein ID: 3822970103

Symbol: TSPO_RAT

Name: Translocator protein

UniProtKB Accession Codes:

P16257

Database IDs:

Citations:

PubMed ID: 2555358

Title: Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor.

PubMed ID: 2555358

DOI: 10.1016/s0021-9258(19)47078-6

PubMed ID: 1332914

Title: Structure of the rat gene encoding the mitochondrial benzodiazepine receptor.

PubMed ID: 1332914

DOI: 10.1016/0378-1119(92)90147-h

PubMed ID: 20336621

Title: In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography.

PubMed ID: 20336621

DOI: 10.1002/syn.20779

Sequence Information:

Length: 169
Mass: 18940
Checksum: 0D750157DB5585AF
Sequence:

MSQSWVPAVG LTLVPSLGGF MGAYFVRGEG LRWYASLQKP SWHPPRWTLA PIWGTLYSAM 
GYGSYIIWKE LGGFTEEAMV PLGLYTGQLA LNWAWPPIFF GARQMGWALV DLMLVSGVAT 
ATTLAWHRVS PPAARLLYPY LAWLAFATML NYYVWRDNSG RRGGSRLTE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.