Genular: Defining Cellular Identity and Function

Details for: Calca

Gene ID: 24241

Symbol: Calca

Ensembl ID: ENSRNOG00000011130

Description: calcitonin-related polypeptide alpha

Associated with

Calcitonin-like ligand receptors
(R-RNO-419812)
Class b/2 (secretin family receptors)
(R-RNO-373080)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure
(GO:0001984)
Axon
(GO:0030424)
Calcitonin gene-related peptide receptor signaling pathway
(GO:1990408)
Calcitonin receptor binding
(GO:0031716)
Cell adhesion
(GO:0007155)
Cellular response to nerve growth factor stimulus
(GO:1990090)
Cellular response to tumor necrosis factor
(GO:0071356)
Cytoplasm
(GO:0005737)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Embryo implantation
(GO:0007566)
Endothelial cell migration
(GO:0043542)
Endothelial cell proliferation
(GO:0001935)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Feeding behavior
(GO:0007631)
G protein-coupled receptor internalization
(GO:0002031)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Intracellular calcium ion homeostasis
(GO:0006874)
Leukocyte cell-cell adhesion
(GO:0007159)
Monocyte chemotaxis
(GO:0002548)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of bone resorption
(GO:0045779)
Negative regulation of calcium ion transport into cytosol
(GO:0010523)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of nervous system process
(GO:0031645)
Negative regulation of ossification
(GO:0030279)
Negative regulation of osteoclast differentiation
(GO:0045671)
Negative regulation of smooth muscle contraction
(GO:0045986)
Nervous system process involved in regulation of systemic arterial blood pressure
(GO:0001976)
Neuromuscular junction development
(GO:0007528)
Neuronal cell body
(GO:0043025)
Neuronal dense core vesicle
(GO:0098992)
Neuron projection
(GO:0043005)
Neuropeptide hormone activity
(GO:0005184)
Neuropeptide signaling pathway
(GO:0007218)
Ossification
(GO:0001503)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of interleukin-1 alpha production
(GO:0032730)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of macrophage differentiation
(GO:0045651)
Positive regulation of ossification
(GO:0045778)
Protein-containing complex binding
(GO:0044877)
Receptor internalization
(GO:0031623)
Regulation of blood pressure
(GO:0008217)
Regulation of cytosolic calcium ion concentration
(GO:0051480)
Regulation of heart rate
(GO:0002027)
Response to heat
(GO:0009408)
Response to pain
(GO:0048265)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Smooth muscle contraction
(GO:0006939)
Terminal bouton
(GO:0043195)
Vasculature development
(GO:0001944)
Vasodilation
(GO:0042311)

Other Information

Proteins

Genular Protein ID: 3414184753

Symbol: CALC_RAT

Name: Calcitonin

UniProtKB Accession Codes:

P01257

Database IDs:

Citations:

PubMed ID: 6264603

Title: Calcitonin messenger RNA encodes multiple polypeptides in a single precursor.

PubMed ID: 6264603

DOI: 10.1126/science.6264603

PubMed ID: 6400492

Title: Alternative RNA processing events as a critical developmental regulatory strategy in neuroendocrine gene expression.

PubMed ID: 6400492

PubMed ID: 6933496

Title: Characterization of rat calcitonin mRNA.

PubMed ID: 6933496

DOI: 10.1073/pnas.77.8.4444

PubMed ID: 1278175

Title: The complete amino-acid sequence of rat thyrocalcitonin.

PubMed ID: 1278175

DOI: 10.1111/j.1432-1033.1976.tb10340.x

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 136
Mass: 15103
Checksum: A197358A802222F7
Sequence:

MGFLKFSPFL VVSILLLYQA CGLQAVPLRS TLESSPGMAT LSEEEARLLA ALVQNYMQMK 
VRELEQEEEQ EAEGSSLDSP RSKRCGNLST CMLGTYTQDL NKFHTFPQTS IGVGAPGKKR 
DMAKDLETNH HPYFGN

Genular Protein ID: 3292100930

Symbol: CALCA_RAT

Name: Calcitonin gene-related peptide 1

UniProtKB Accession Codes:

P01256

Database IDs:

Citations:

PubMed ID: 3872459

Title: Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression.

PubMed ID: 3872459

DOI: 10.1073/pnas.82.7.1994

PubMed ID: 6283379

Title: Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products.

PubMed ID: 6283379

DOI: 10.1038/298240a0

PubMed ID: 2994212

Title: Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide.

PubMed ID: 2994212

DOI: 10.1126/science.2994212

Sequence Information:

Length: 128
Mass: 13948
Checksum: 75D14869C17078D3
Sequence:

MGFLKFSPFL VVSILLLYQA CGLQAVPLRS TLESSPGMAA TLSEEEARLL LAALVQNYMQ 
MKVRELEQEQ EAEGSSVTAQ KRSCNTATCV THRLAGLLSR SGGVVKDNFV PTNVGSEAFG 
RRRRDLQA

Genular Protein ID: 3873316520

Symbol: A6I8B3_RAT

Name: N/A

UniProtKB Accession Codes:

A6I8B3

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 128
Mass: 14022
Checksum: 1B159285D219949C
Sequence:

MGFLKFSPFL VVSILLLYQA CGLQAVPLRS TLESSPGMAT LSEEEARLLA ALVQNYMQMK 
VRELEQEEEQ EAEGSSVTAQ KRSCNTATCV THRLAGLLSR SGGVVKDNFV PTNVGSEAFG 
RRRRDLQA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Calca

Associated with

Other Information

Calcitonin messenger RNA encodes multiple polypeptides in a single precursor. PubMed ID: 6264603

Alternative RNA processing events as a critical developmental regulatory strategy in neuroendocrine gene expression. PubMed ID: 6400492

Characterization of rat calcitonin mRNA. PubMed ID: 6933496

The complete amino-acid sequence of rat thyrocalcitonin. PubMed ID: 1278175

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression. PubMed ID: 3872459

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. PubMed ID: 6283379

Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. PubMed ID: 2994212

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Database document:

PubMed ID: 6264603

PubMed ID: 6400492

PubMed ID: 6933496

PubMed ID: 1278175

PubMed ID: 22673903

PubMed ID: 3872459

PubMed ID: 6283379

PubMed ID: 2994212

PubMed ID: 15632090