Genular: Defining Cellular Identity and Function

Details for: Cbs

Gene ID: 24250

Symbol: Cbs

Ensembl ID: ENSRNOG00000029528

Description: cystathionine beta synthase

Associated with

Cysteine formation from homocysteine
(R-RNO-1614603)
Metabolism
(R-RNO-1430728)
Metabolism of amino acids and derivatives
(R-RNO-71291)
Sulfur amino acid metabolism
(R-RNO-1614635)
Blood vessel diameter maintenance
(GO:0097746)
Blood vessel remodeling
(GO:0001974)
Carbon monoxide binding
(GO:0070025)
Cartilage development involved in endochondral bone morphogenesis
(GO:0060351)
Cellular response to hypoxia
(GO:0071456)
Cerebellum morphogenesis
(GO:0021587)
Cystathionine beta-synthase activity
(GO:0004122)
Cysteine biosynthetic process
(GO:0019344)
Cysteine biosynthetic process from serine
(GO:0006535)
Cysteine biosynthetic process via cystathionine
(GO:0019343)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna protection
(GO:0042262)
Endochondral ossification
(GO:0001958)
Enzyme binding
(GO:0019899)
Heme binding
(GO:0020037)
Homocysteine catabolic process
(GO:0043418)
Homocysteine metabolic process
(GO:0050667)
Hydrogen sulfide biosynthetic process
(GO:0070814)
Identical protein binding
(GO:0042802)
L-cysteine catabolic process
(GO:0019448)
L-serine catabolic process
(GO:0006565)
L-serine metabolic process
(GO:0006563)
Maternal process involved in female pregnancy
(GO:0060135)
Metal ion binding
(GO:0046872)
Modified amino acid binding
(GO:0072341)
Negative regulation of apoptotic process
(GO:0043066)
Nitric oxide binding
(GO:0070026)
Nitrite reductase (no-forming) activity
(GO:0050421)
Nucleus
(GO:0005634)
Oxygen binding
(GO:0019825)
Protein homodimerization activity
(GO:0042803)
Pyridoxal phosphate binding
(GO:0030170)
Regulation of nitric oxide mediated signal transduction
(GO:0010749)
Response to folic acid
(GO:0051593)
Response to nutrient levels
(GO:0031667)
S-adenosyl-l-methionine binding
(GO:1904047)
Superoxide metabolic process
(GO:0006801)
Transsulfuration
(GO:0019346)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Beta-thionase
A6JK04_RAT

Genular Protein ID: 1816157931

Symbol: CBS_RAT

Name: Beta-thionase

UniProtKB Accession Codes:

P32232

Database IDs:

Citations:

PubMed ID: 1597473

Title: Rat cystathionine beta-synthase. Gene organization and alternative splicing.

PubMed ID: 1597473

DOI: 10.1016/s0021-9258(19)49931-6

PubMed ID: 2089036

Title: Molecular cloning and sequence analysis of cDNA coding for rat liver hemoprotein H-450.

PubMed ID: 2089036

DOI: 10.1093/oxfordjournals.jbchem.a123310

PubMed ID: 8558235

Title: The possible role of hydrogen sulfide as an endogenous neuromodulator.

PubMed ID: 8558235

DOI: 10.1523/jneurosci.16-03-01066.1996

PubMed ID: 20149843

Title: Hydrogen sulfide protects neurons against hypoxic injury via stimulation of ATP-sensitive potassium channel/protein kinase C/extracellular signal-regulated kinase/heat shock protein 90 pathway.

PubMed ID: 20149843

DOI: 10.1016/j.neuroscience.2010.02.006

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 561
Mass: 61455
Checksum: 0199FCAF492AE3A2
Sequence:

MPSGTSQCED GSAGCPQDLE VQPEKGQLEK GASGDKERVW ISPDTPSRCT WQLGRPMADS 
PHYHTVPTKS PKILPDILRK IGNTPMVRIN RISKNAGLKC ELLAKCEFFN AGGSVKDRIS 
LRMIEDAERA GTLKPGDTII EPTSGNTGIG LALAAAVKGY RCIIVMPEKM SMEKVDVLRA 
LGAEIVRTPT NARFDSPESH VGVAWRLKNE IPNSHILDQY RNASNPLAHY DDTAEEILQQ 
CDGKVDMLVA SAGTGGTITG IARKLKEKCP GCKIIGVDPE GSILAEPEEL NQTEQTAYEV 
EGIGYDFIPT VLDRAVVDRW FKSNDDDSFA FARMLISQEG LLCGGSSGSA MAVAVKAAQE 
LKEGQRCVVI LPDSVRNYMS KFLSDKWMLQ KGFMKEELSV KRPWWWHLRV QELSLSAPLT 
VLPTVTCEHT IAILREKGFD QAPVVNESGA ILGMVTLGNM LSSLLAGKVR PSDEVCKVLY 
KQFKPIHLTD TLGMLSHILE MDHFALVVHE QIQSRDQAWS GVVGGPTDRN NGVSSKQLMV 
FGVVTAIDLL NFVAAREQTR K

Genular Protein ID: 2716351447

Symbol: A6JK04_RAT

Name: N/A

UniProtKB Accession Codes:

A6JK04

Database IDs:

Sequence Information:

Length: 547
Mass: 60104
Checksum: A71FF5D43137A5E1
Sequence:

MPSGTSQCED GSAGCPQDLE VQPEKGQLEK GASGDKERVW ISPDTPSRCT WQLGRPMADS 
PHYHTVPTKS PKILPDILRK IGNTPMVRIN RISKNAGLKC ELLAKCEFFN AGGSVKDRIS 
LRMIEDAERA GTLKPGDTII EPTSGNTGIG LALAAAVKGY RCIIVMPEKM SMEKVDVLRA 
LGAEIVRTPT NARFDSPESH VGVAWRLKNE IPNSHILDQY RNASNPLAHY DDTAEEILQQ 
CDGKVDMLVA SAGTGGTITG IARKLKEKCP GCKIIGVDPE GSILAEPEEL NQTEQTAYEV 
EGIGYDFIPT VLDRAVVDRW FKSNDDDSFA FARMLISQEG LLCGGSSGSA MAVAVKAAQE 
LKEGQRCVVI LPDSVRNYMS KFLSDKWMLQ KGFMKEELSV KRPWWWHLRV QELSLSAPLT 
VLPTVTCEHT IAILREKGFD QAPVVNESGA ILGMVTLGNM LSSLLAGKVR PSDEVCKVLY 
KQFKPIHLTD TLGMLSHILE MDHFALVVHE QIQYRNNGVS SKQLMVFGVV TAIDLLNFVA 
AREQTRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cbs

Associated with

Other Information

Rat cystathionine beta-synthase. Gene organization and alternative splicing. PubMed ID: 1597473

Molecular cloning and sequence analysis of cDNA coding for rat liver hemoprotein H-450. PubMed ID: 2089036

The possible role of hydrogen sulfide as an endogenous neuromodulator. PubMed ID: 8558235