Details for: Cebpb

Gene ID: 24253

Symbol: Cebpb

Description: CCAAT/enhancer binding protein beta

Associated with

  • Brown fat cell differentiation
    (GO:0050873)
  • C/ebp complex
    (GO:1990647)
  • Cellular response to amino acid stimulus
    (GO:0071230)
  • Cellular response to interleukin-1
    (GO:0071347)
  • Cellular response to lipopolysaccharide
    (GO:0071222)
  • Cellular response to organic cyclic compound
    (GO:0071407)
  • Chop-c/ebp complex
    (GO:0036488)
  • Chromatin
    (GO:0000785)
  • Chromatin binding
    (GO:0003682)
  • Chromatin dna binding
    (GO:0031490)
  • Condensed chromosome, centromeric region
    (GO:0000779)
  • Cytoplasm
    (GO:0005737)
  • Defense response to bacterium
    (GO:0042742)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Embryonic placenta development
    (GO:0001892)
  • Fat cell differentiation
    (GO:0045444)
  • Granuloma formation
    (GO:0002432)
  • Hepatocyte proliferation
    (GO:0072574)
  • Histone acetyltransferase binding
    (GO:0035035)
  • Histone deacetylase binding
    (GO:0042826)
  • Identical protein binding
    (GO:0042802)
  • Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
    (GO:0070059)
  • Kinase binding
    (GO:0019900)
  • Liver development
    (GO:0001889)
  • Liver regeneration
    (GO:0097421)
  • Mammary gland epithelial cell differentiation
    (GO:0060644)
  • Mammary gland epithelial cell proliferation
    (GO:0033598)
  • Memory
    (GO:0007613)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Negative regulation of t cell proliferation
    (GO:0042130)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuron differentiation
    (GO:0030182)
  • Nuclear glucocorticoid receptor binding
    (GO:0035259)
  • Nuclear matrix
    (GO:0016363)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Ovarian follicle development
    (GO:0001541)
  • Positive regulation of biomineral tissue development
    (GO:0070169)
  • Positive regulation of cold-induced thermogenesis
    (GO:0120162)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of fat cell differentiation
    (GO:0045600)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of inflammatory response
    (GO:0050729)
  • Positive regulation of interleukin-4 production
    (GO:0032753)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of sodium-dependent phosphate transport
    (GO:2000120)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of cell differentiation
    (GO:0045595)
  • Regulation of dendritic cell differentiation
    (GO:2001198)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of interleukin-6 production
    (GO:0032675)
  • Regulation of odontoblast differentiation
    (GO:1901329)
  • Regulation of osteoclast differentiation
    (GO:0045670)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to endoplasmic reticulum stress
    (GO:0034976)
  • Response to lipopolysaccharide
    (GO:0032496)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii core promoter sequence-specific dna binding
    (GO:0000979)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • T-helper 1 cell activation
    (GO:0035711)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Ubiquitin-like protein ligase binding
    (GO:0044389)

Other Information

Genular Protein ID: 257312308

Symbol: CEBPB_RAT

Name: C/EBP-related protein 2

UniProtKB Accession Codes:

P21272 A2VD03

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 CDD 1 CTD 1 ComplexPortal 2 DIP 1 EMBL 5 GO 75 Gene3D 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 2 Reactome 1 RefSeq 3 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2171780

Title: IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP.

PubMed ID: 2171780

DOI: 10.1016/0092-8674(90)90459-r

PubMed ID: 2253878

Title: LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

PubMed ID: 2253878

DOI: 10.1101/gad.4.9.1541

PubMed ID: 1377818

Title: Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma.

PubMed ID: 1377818

DOI: 10.1093/nar/20.12.3091

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1884998

Title: A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

PubMed ID: 1884998

DOI: 10.1101/gad.5.9.1553

PubMed ID: 1934061

Title: A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA.

PubMed ID: 1934061

DOI: 10.1016/0092-8674(91)90531-3

PubMed ID: 8336793

Title: Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain.

PubMed ID: 8336793

DOI: 10.1038/364544a0

PubMed ID: 10635333

Title: Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha.

PubMed ID: 10635333

DOI: 10.1016/s1097-2765(00)80237-3

PubMed ID: 15308669

Title: The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation.

PubMed ID: 15308669

DOI: 10.1074/jbc.m405031200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 297
  • Mass: 31503
  • Checksum: C2511FDB65527789
  • Sequence:
    • MHRLLAWDAA CLPPPPAAFR PMEVANFYYE PDCLAYGAKA ARAAPRAPAA EPAIGEHERA 
IDFSPYLEPL APAAADFAAP APAHHDFLSD LFADDYGAKP SKKPSDYGYV SLGRAGAKAA 
PPACFPPPPP AALKAEPGFE PADCKRADDA PAMAAGFPFA LRAYLGYQAT PSGSSGSLST 
SSSSSPPGTP SPADAKAAPA ACFAGPPAAP AKAKAKKAVD KLSDEYKMRR ERNNIAVRKS 
RDKAKMRNLE TQHKVLELTA ENERLQKKVE QLSRELSTLR NLFKQLPEPL LASAGHC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.