Genular: Defining Cellular Identity and Function

Details for: Cryaa

Gene ID: 24273

Symbol: Cryaa

Description: crystallin, alpha A

Associated with

Actin filament organization
(GO:0007015)
Apoptotic process
(GO:0006915)
Apoptotic process involved in morphogenesis
(GO:0060561)
Camera-type eye development
(GO:0043010)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Embryonic camera-type eye morphogenesis
(GO:0048596)
Identical protein binding
(GO:0042802)
Lens development in camera-type eye
(GO:0002088)
Lens fiber cell morphogenesis
(GO:0070309)
Lens morphogenesis in camera-type eye
(GO:0002089)
Metal ion binding
(GO:0046872)
Microtubule-based process
(GO:0007017)
Mitochondrion organization
(GO:0007005)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of intracellular transport
(GO:0032387)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein refolding
(GO:0042026)
Protein stabilization
(GO:0050821)
Response to glucocorticoid
(GO:0051384)
Response to heat
(GO:0009408)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to lead ion
(GO:0010288)
Response to uv-a
(GO:0070141)
Response to xenobiotic stimulus
(GO:0009410)
Structural constituent of eye lens
(GO:0005212)
Structural molecule activity
(GO:0005198)
Tubulin complex assembly
(GO:0007021)
Unfolded protein binding
(GO:0051082)
Visual perception
(GO:0007601)

Other Information

Proteins

Alpha-crystallin A chain
A0JN13_RAT

Genular Protein ID: 2567785435

Symbol: CRYAA_RAT

Name: Alpha-crystallin A chain

UniProtKB Accession Codes:

P24623 P02490 P02496 P82532 Q61444

Database IDs:

Citations:

PubMed ID: 2294971

Title: The alternative splicing product alpha Ains-crystallin is structurally equivalent to alpha A and alpha B subunits in the rat alpha-crystallin aggregate.

PubMed ID: 2294971

DOI: 10.1016/0167-4838(90)90101-k

PubMed ID: 8875649

Title: Expression of recombinant alpha Ains-crystallin and not alpha A-crystallin inhibits bacterial growth.

PubMed ID: 8875649

DOI: 10.1093/protein/9.8.713

PubMed ID: 6171772

Title: An unusually long non-coding region in rat lens alpha-crystallin messenger RNA.

PubMed ID: 6171772

DOI: 10.1093/nar/9.19.4813

PubMed ID: 1429679

Title: Alpha A-crystallin is expressed in non-ocular tissues.

PubMed ID: 1429679

DOI: 10.1016/s0021-9258(18)50096-x

PubMed ID: 699911

Title: Rat alpha-crystallin A chain with an insertion of 22 residues.

PubMed ID: 699911

DOI: 10.1111/j.1432-1033.1978.tb20921.x

PubMed ID: 12356833

Title: Enhanced C-terminal truncation of alphaA- and alphaB-crystallins in diabetic lenses.

PubMed ID: 12356833

PubMed ID: 12118077

Title: Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens.

PubMed ID: 12118077

DOI: 10.1074/mcp.m200007-mcp200

Sequence Information:

Length: 196
Mass: 22447
Checksum: D0C0E0DFA82D551C
Sequence:

MDVTIQHPWF KRALGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG 
ISELMTHMWF VMHQPHAGNP KNNPGKVRSD RDKFVIFLDV KHFSPEDLTV KVLEDFVEIH 
GKHNERQDDH GYISREFHRR YRLPSNVDQS ALSCSLSADG MLTFSGPKVQ SGLDAGHSER 
AIPVSREEKP SSAPSS

Genular Protein ID: 2702500164

Symbol: A0JN13_RAT

Name: N/A

UniProtKB Accession Codes:

A0JN13

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 173
Mass: 19792
Checksum: E146E3F488591F93
Sequence:

MDVTIQHPWF KRALGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG 
ISEVRSDRDK FVIFLDVKHF SPEDLTVKVL EDFVEIHGKH NERQDDHGYI SREFHRRYRL 
PSNVDQSALS CSLSADGMLT FSGPKVQSGL DAGHSERAIP VSREEKPSSA PSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cryaa

Associated with

Other Information

The alternative splicing product alpha Ains-crystallin is structurally equivalent to alpha A and alpha B subunits in the rat alpha-crystallin aggregate. PubMed ID: 2294971

Expression of recombinant alpha Ains-crystallin and not alpha A-crystallin inhibits bacterial growth. PubMed ID: 8875649

An unusually long non-coding region in rat lens alpha-crystallin messenger RNA. PubMed ID: 6171772

Alpha A-crystallin is expressed in non-ocular tissues. PubMed ID: 1429679

Rat alpha-crystallin A chain with an insertion of 22 residues. PubMed ID: 699911

Enhanced C-terminal truncation of alphaA- and alphaB-crystallins in diabetic lenses. PubMed ID: 12356833

Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens. PubMed ID: 12118077

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090