Genular: Defining Cellular Identity and Function

Details for: Ednra

Gene ID: 24326

Symbol: Ednra

Ensembl ID: ENSRNOG00000012721

Description: endothelin receptor type A

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Angiogenesis
(GO:0001525)
Aorta development
(GO:0035904)
Artery smooth muscle contraction
(GO:0014824)
Atrial cardiac muscle tissue development
(GO:0003228)
Axon extension
(GO:0048675)
Axon guidance
(GO:0007411)
Axonogenesis involved in innervation
(GO:0060385)
Blood vessel remodeling
(GO:0001974)
Branching involved in blood vessel morphogenesis
(GO:0001569)
Calcium ion transmembrane transport
(GO:0070588)
Canonical wnt signaling pathway
(GO:0060070)
Cardiac chamber formation
(GO:0003207)
Cardiac neural crest cell migration involved in outflow tract morphogenesis
(GO:0003253)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Cellular response to human chorionic gonadotropin stimulus
(GO:0044751)
Cellular response to luteinizing hormone stimulus
(GO:0071373)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to organic substance
(GO:0071310)
Cellular response to oxidative stress
(GO:0034599)
Developmental pigmentation
(GO:0048066)
Embryonic heart tube development
(GO:0035050)
Embryonic skeletal system development
(GO:0048706)
Endothelin receptor activity
(GO:0004962)
Endothelin receptor signaling pathway
(GO:0086100)
Endothelin receptor signaling pathway involved in heart process
(GO:0086101)
Enteric nervous system development
(GO:0048484)
Establishment of endothelial barrier
(GO:0061028)
Face development
(GO:0060324)
Fibroblast proliferation
(GO:0048144)
Gene expression
(GO:0010467)
Glomerular endothelium development
(GO:0072011)
Glomerular filtration
(GO:0003094)
Glomerulus development
(GO:0032835)
Head development
(GO:0060322)
Heart development
(GO:0007507)
Heart process
(GO:0003015)
Heparin metabolic process
(GO:0030202)
Histamine secretion
(GO:0001821)
Intracellular calcium ion homeostasis
(GO:0006874)
Intracellular signal transduction
(GO:0035556)
In utero embryonic development
(GO:0001701)
Left ventricular cardiac muscle tissue morphogenesis
(GO:0003220)
Maternal process involved in parturition
(GO:0060137)
Middle ear morphogenesis
(GO:0042474)
Mitochondrion organization
(GO:0007005)
Mitotic cell cycle
(GO:0000278)
Negative regulation of apoptotic process
(GO:0043066)
Neural crest cell development
(GO:0014032)
Neural crest cell differentiation
(GO:0014033)
Neural crest cell fate commitment
(GO:0014034)
Neuromuscular process
(GO:0050905)
Neuron projection development
(GO:0031175)
Neuron remodeling
(GO:0016322)
Noradrenergic neuron differentiation
(GO:0003357)
Norepinephrine metabolic process
(GO:0042415)
Pharyngeal arch artery morphogenesis
(GO:0061626)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Podocyte differentiation
(GO:0072112)
Positive regulation of calcium ion transport
(GO:0051928)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Positive regulation of odontogenesis
(GO:0042482)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of release of sequestered calcium ion into cytosol
(GO:0051281)
Protein kinase a signaling
(GO:0010737)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Protein transmembrane transport
(GO:0071806)
Regulation of blood pressure
(GO:0008217)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of glucose transmembrane transport
(GO:0010827)
Regulation of heart rate
(GO:0002027)
Renal sodium ion absorption
(GO:0070294)
Respiratory gaseous exchange by respiratory system
(GO:0007585)
Response to amphetamine
(GO:0001975)
Response to hypoxia
(GO:0001666)
Response to lipopolysaccharide
(GO:0032496)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to wounding
(GO:0009611)
Rho protein signal transduction
(GO:0007266)
Smooth muscle cell proliferation
(GO:0048659)
Sodium ion homeostasis
(GO:0055078)
Sympathetic nervous system development
(GO:0048485)
Thyroid gland development
(GO:0030878)
Vasoconstriction
(GO:0042310)

Other Information

Proteins

Genular Protein ID: 2448898526

Symbol: EDNRA_RAT

Name: N/A

UniProtKB Accession Codes:

P26684

Database IDs:

Citations:

PubMed ID: 1312429

Title: Distinct tissue distribution and cellular localization of two messenger ribonucleic acids encoding different subtypes of rat endothelin receptors.

PubMed ID: 1312429

DOI: 10.1210/endo.130.4.1312429

PubMed ID: 1849646

Title: Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor.

PubMed ID: 1849646

DOI: 10.1073/pnas.88.8.3185

Sequence Information:

Length: 426
Mass: 48245
Checksum: E8A24683DBB78BB8
Sequence:

MGVLCFLASF WLALVGGAIA DNAERYSANL SSHVEDFTPF PGTEFNFLGT TLQPPNLALP 
SNGSMHGYCP QQTKITTAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC MRNGPNALIA 
SLALGDLIYV VIDLPINVFK LLAGRWPFDH NDFGVFLCKL FPFLQKSSVG ITVLNLCALS 
VDRYRAVASW SRVQGIGIPL ITAIEIVSIW ILSFILAIPE AIGFVMVPFE YKGEQHRTCM 
LNATTKFMEF YQDVKDWWLF GFYFCMPLVC TAIFYTLMTC EMLNRRNGSL RIALSEHLKQ 
RREVAKTVFC LVVIFALCWF PLHLSRILKK TVYDEMDKNR CELLSFLLLM DYIGINLATM 
NSCINPIALY FVSKKFKNCF QSCLCCCCHQ SKSLMTSVPM NGTSIQWKNQ EQNHNTERSS 
HKDSMN

Genular Protein ID: 2852077060

Symbol: A0A0G2JSX5_RAT

Name: N/A

UniProtKB Accession Codes:

A0A0G2JSX5

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

Length: 426
Mass: 48274
Checksum: 4B2FEC4DA598B97D
Sequence:

MGVLCFLASF WLALVGGAIA DNAERYSANL SSHVEDFTPF PGTEFDFLGT TLRPPNLALP 
SNGSMHGYCP QQTKITTAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC MRNGPNALIA 
SLALGDLIYV VIDLPINVFK LLAGRWPFDH NDFGVFLCKL FPFLQKSSVG ITVLNLCALS 
VDRYRAVASW SRVQGIGIPL ITAIEIVSIW ILSFILAIPE AIGFVMVPFE YKGEQHRTCM 
LNATTKFMEF YQDVKDWWLF GFYFCMPLVC TAIFYTLMTC EMLNRRNGSL RIALSEHLKQ 
RREVAKTVFC LVVIFALCWF PLHLSRILKK TVYDEMDKNR CELLSFLLLM DYIGINLATM 
NSCINPIALY FVSKKFKNCF QSCLCCCCHQ SKSLMTSVPM NGTSIQWKNQ EQNHNTERSS 
HKDSMN

Genular Protein ID: 2818303551

Symbol: A1Y2B8_RAT

Name: N/A

UniProtKB Accession Codes:

A1Y2B8

Database IDs:

Citations:

PubMed ID: 17312275

Title: Cloning and functional identification of novel endothelin receptor type A isoforms in pituitary.

PubMed ID: 17312275

DOI: 10.1210/me.2006-0343

Sequence Information:

Length: 399
Mass: 45298
Checksum: 27CFB3A03A271F4F
Sequence:

MGVLCFLASF WLALVGGAIA DNAERYSANL SSHVEDFTPF PGTEFDFLGT TLRPPNLALP 
SNGSMHGYCP QQTKITTAFK YINTVISCTI FIVGMVGNAT LLRIIYQNKC MRNGPNALIA 
SLALGDLIYV VIDLPINVFK LLAGRWPFDH NDFGVFLCKL FPFLQKSSVG ITVLNLCALS 
VDRYRAVASW SRVQGIGIPL ITAIEIVSIW ILSFILAIPE AIGFVMVPFE YKGEQHRTCM 
LNATTKFMEF YQDVKDWWLF GFYFCMPLVC TAIFYTLMTC EMLNRRNGSL RIALSEHLKQ 
RREVAKTVFC LVVIFALCWF PLHLSRILKK TVYDEMDKNR CELLSFLLLM DYIGINLATM 
NSCINPIALY FVSKKFKNCF QALLWSFIKR CQQHPQLGL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ednra

Associated with

Other Information

Distinct tissue distribution and cellular localization of two messenger ribonucleic acids encoding different subtypes of rat endothelin receptors. PubMed ID: 1312429

Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor. PubMed ID: 1849646

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

Cloning and functional identification of novel endothelin receptor type A isoforms in pituitary. PubMed ID: 17312275

Database document:

PubMed ID: 1312429

PubMed ID: 1849646

PubMed ID: 15057822

PubMed ID: 17312275