Genular: Defining Cellular Identity and Function

Details for: Egfr

Gene ID: 24329

Symbol: Egfr

Ensembl ID: ENSRNOG00000004332

Description: epidermal growth factor receptor

Associated with

Axon guidance
(R-RNO-422475)
Cargo recognition for clathrin-mediated endocytosis
(R-RNO-8856825)
Clathrin-mediated endocytosis
(R-RNO-8856828)
Developmental biology
(R-RNO-1266738)
Downregulation of erbb2 signaling
(R-RNO-8863795)
Egfr downregulation
(R-RNO-182971)
Egfr interacts with phospholipase c-gamma
(R-RNO-212718)
Egfr transactivation by gastrin
(R-RNO-2179392)
Erbb2 activates ptk6 signaling
(R-RNO-8847993)
Erbb2 regulates cell motility
(R-RNO-6785631)
Esr-mediated signaling
(R-RNO-8939211)
Extra-nuclear estrogen signaling
(R-RNO-9009391)
Gab1 signalosome
(R-RNO-180292)
G alpha (q) signalling events
(R-RNO-416476)
Gastrin-creb signalling pathway via pkc and mapk
(R-RNO-881907)
Gpcr downstream signalling
(R-RNO-388396)
Grb2 events in egfr signaling
(R-RNO-179812)
Intracellular signaling by second messengers
(R-RNO-9006925)
L1cam interactions
(R-RNO-373760)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Membrane trafficking
(R-RNO-199991)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Nervous system development
(R-RNO-9675108)
Notch3 activation and transmission of signal to the nucleus
(R-RNO-9013507)
Pi3k events in erbb2 signaling
(R-RNO-1963642)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Ptk6 promotes hif1a stabilization
(R-RNO-8857538)
Raf/map kinase cascade
(R-RNO-5673001)
Shc1 events in egfr signaling
(R-RNO-180336)
Shc1 events in erbb2 signaling
(R-RNO-1250196)
Signaling by egfr
(R-RNO-177929)
Signaling by erbb2
(R-RNO-1227986)
Signaling by erbb4
(R-RNO-1236394)
Signaling by gpcr
(R-RNO-372790)
Signaling by non-receptor tyrosine kinases
(R-RNO-9006927)
Signaling by notch
(R-RNO-157118)
Signaling by notch3
(R-RNO-9012852)
Signaling by nuclear receptors
(R-RNO-9006931)
Signaling by ptk6
(R-RNO-8848021)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signal transduction by l1
(R-RNO-445144)
Vesicle-mediated transport
(R-RNO-5653656)
Actin filament binding
(GO:0051015)
Atp binding
(GO:0005524)
Calmodulin binding
(GO:0005516)
Cell morphogenesis
(GO:0000902)
Cell population proliferation
(GO:0008283)
Cell surface receptor signaling pathway
(GO:0007166)
Chromatin binding
(GO:0003682)
Circadian rhythm
(GO:0007623)
Diterpenoid metabolic process
(GO:0016101)
Embryonic placenta development
(GO:0001892)
Enzyme binding
(GO:0019899)
Epidermal growth factor binding
(GO:0048408)
Epidermal growth factor receptor activity
(GO:0005006)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Epidermis development
(GO:0008544)
Hair follicle development
(GO:0001942)
Identical protein binding
(GO:0042802)
Integrin binding
(GO:0005178)
Kinase activity
(GO:0016301)
Kinase binding
(GO:0019900)
Learning or memory
(GO:0007611)
Liver development
(GO:0001889)
Midgut development
(GO:0007494)
Multicellular organism development
(GO:0007275)
Nitric-oxide synthase regulator activity
(GO:0030235)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of nitric oxide mediated signal transduction
(GO:0010750)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein phosphatase binding
(GO:0019903)
Protein tyrosine kinase activator activity
(GO:0030296)
Protein tyrosine kinase activity
(GO:0004713)
Receptor-mediated endocytosis
(GO:0006898)
Response to organic cyclic compound
(GO:0014070)
Response to oxidative stress
(GO:0006979)
Salivary gland morphogenesis
(GO:0007435)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Translation
(GO:0006412)
Transmembrane receptor protein tyrosine kinase activator activity
(GO:0030297)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Transmembrane signaling receptor activity
(GO:0004888)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Q9QX70_RAT

Genular Protein ID: 3655332686

Symbol: Q9QX70_RAT

Name: N/A

UniProtKB Accession Codes:

Q9QX70

Database IDs:

Citations:

PubMed ID: 2342466

Title: A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue.

PubMed ID: 2342466

DOI: 10.1128/MCB.10.6.2973

Sequence Information:

Length: 1209
Mass: 134891
Checksum: 96FEE7F6CC1B7773
Sequence:

MRPSGTARTK LLLLLAALCA AGGALEEKKV CQGTSNRLTQ LGTFEDHFLS LQRMFNNCEV 
VLGNLEITYV QRNYDLSFLK TIQEVAGYVL IALNTVERIP LENLQIIRGN ALYENTYALA 
VLSNYGTNKT GLRELPMRNL QEILIGAVRF SNNPILCNME TIQWRDIVQD VFLSNMSMDV 
QRHLTGCPKC DPSCPNGSCW GRGEENCQKL TKIICAQQCS RRCRGRSPSD CCHNQCAAGC 
TGPRESDCLV CHRFRDEATC KDTCPPLMLY NPTTYQMDVN PEGKYSFGAT CVKKCPRNYV 
VTDHGSCVRA CGPDYYEVEE DGVSKCKKCD GPCRKVCNGI GIGEFKDTLS INATNIKHFK 
YCTAISGDLH ILPVAFKGDS FTRTPPLDPR ELEILKTVKE ITGFLLIQAW PENWTDLHAF 
ENLEIIRGRT KQHGQFSLAV VGLNITSLGL RSLKEISDGD VIISGNRNLC YANTINWKKL 
FGTPNQKTKI MNNRAEKDCK ATNHVCNPLC SSEGCWGPEP TDCVSCQNVS RGRECVDKCN 
ILEGEPREFV ENSECIQCHP ECLPQTMNIT CTGRGPDNCI KCAHYVDGPH CVKTCPSGIM 
GENNTLVWKF ADANNVCHLC HANCTYGCAG PGLKGCQQPE GPKIPSIATG IVGGLLFIVV 
VALGIGLFMR RRQLVRKRTL RRLLQERELV EPLTPSGEAP NQAHLRILKE TEFKKIKVLG 
SGAFGTVYKG LWIPEGEKVK IPVAIKELRE ATSPKANKEI LDEAYVMASV DNPHVCRLLG 
ICLTSTVQLI TQLMPYGCLL DYVREHKDNI GSQYLLNWCV QIAKGMNYLE DRRLVHRDLA 
ARNVLVKTPQ HVKITDFGLA KLLGAEEKEY HAEGGKVPIK WMALESILHR IYTHQSDVWS 
YGVTVWELMT FGSKPYDGIP ASEISSILEK GERLPQPPIC TIDVYMIMVK CWMIDADSRP 
KFRELILEFS KMARDPQRYL VIQGDERMHL PSPTDSNFYR ALMEEEDMED VVDADEYLIP 
QQGFFNSPST SRTPLLSSLS ANSNSSTVAC INRNGSCRVK EDAFLQRYSS DPTSVLTEDN 
IDDTFLPVPE YINQSVPKRP AGSVQNPVYH NQPLHPAPGR DLHYQNPHSN AVSNPEYLNT 
AQPTCLSSGF DSSALWIQKG SHQMSLDNPD YQQDFFPKEA KPNGIFKGPT AENAEYLRVA 
PPSSEFSGA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Egfr

Associated with

Other Information

A truncated, secreted form of the epidermal growth factor receptor is encoded by an alternatively spliced transcript in normal rat tissue. PubMed ID: 2342466

Database document:

PubMed ID: 2342466