Genular: Defining Cellular Identity and Function

Details for: Epo

Gene ID: 24335

Symbol: Epo

Ensembl ID: ENSRNOG00000001412

Description: erythropoietin

Associated with

Erythropoietin activates phosphoinositide-3-kinase (pi3k)
(R-RNO-9027276)
Erythropoietin activates ras
(R-RNO-9027284)
Signaling by erythropoietin
(R-RNO-9006335)
Signal transduction
(R-RNO-162582)
Acute-phase response
(GO:0006953)
Apoptotic process
(GO:0006915)
Cell body
(GO:0044297)
Cell surface
(GO:0009986)
Cellular hyperosmotic response
(GO:0071474)
Cytokine activity
(GO:0005125)
Embryo implantation
(GO:0007566)
Erythrocyte differentiation
(GO:0030218)
Erythrocyte maturation
(GO:0043249)
Erythropoietin-mediated signaling pathway
(GO:0038162)
Erythropoietin receptor binding
(GO:0005128)
Extracellular space
(GO:0005615)
Hemoglobin biosynthetic process
(GO:0042541)
Hormone activity
(GO:0005179)
Myeloid cell apoptotic process
(GO:0033028)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of calcium ion transport into cytosol
(GO:0010523)
Negative regulation of erythrocyte apoptotic process
(GO:1902251)
Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
(GO:1902219)
Negative regulation of myeloid cell apoptotic process
(GO:0033033)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Positive regulation of activated t cell proliferation
(GO:0042104)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of ras protein signal transduction
(GO:0046579)
Positive regulation of tyrosine phosphorylation of stat protein
(GO:0042531)
Protein kinase activator activity
(GO:0030295)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to axon injury
(GO:0048678)
Response to dexamethasone
(GO:0071548)
Response to electrical stimulus
(GO:0051602)
Response to estrogen
(GO:0043627)
Response to hyperoxia
(GO:0055093)
Response to hypoxia
(GO:0001666)
Response to interleukin-1
(GO:0070555)
Response to lipopolysaccharide
(GO:0032496)
Response to nutrient
(GO:0007584)
Response to salt stress
(GO:0009651)
Response to testosterone
(GO:0033574)
Response to vitamin a
(GO:0033189)

Other Information

Proteins

Erythropoietin

Genular Protein ID: 3362897101

Symbol: EPO_RAT

Name: Erythropoietin

UniProtKB Accession Codes:

P29676 P70504

Database IDs:

Citations:

PubMed ID: 1420369

Title: Nucleotide sequence of rat erythropoietin.

PubMed ID: 1420369

DOI: 10.1016/0167-4781(92)90146-q

PubMed ID: 8364201

Title: Erythropoietin structure-function relationships: high degree of sequence homology among mammals.

PubMed ID: 8364201

Sequence Information:

Length: 192
Mass: 21286
Checksum: 3EA632737E7D2443
Sequence:

MGVPERPTLL LLLSLLLIPL GLPVLCAPPR LICDSRVLER YILEAKEAEN VTMGCAEGPR 
LSENITVPDT KVNFYAWKRM KVEEQAVEVW QGLSLLSEAI LQAQALQANS SQPPESLQLH 
IDKAISGLRS LTSLLRVLGA QKELMSPPDA TQAAPLRTLT ADTFCKLFRV YSNFLRGKLK 
LYTGEACRRG DR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.