Genular: Defining Cellular Identity and Function

Details for: Erbb2

Gene ID: 24337

Symbol: Erbb2

Ensembl ID: ENSRNOG00000006450

Description: erb-b2 receptor tyrosine kinase 2

Associated with

Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Basal plasma membrane
(GO:0009925)
Basolateral plasma membrane
(GO:0016323)
Cell projection
(GO:0042995)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to epidermal growth factor stimulus
(GO:0071364)
Cellular response to growth factor stimulus
(GO:0071363)
Coreceptor activity
(GO:0015026)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Early endosome
(GO:0005769)
Endosome membrane
(GO:0010008)
Erbb-3 class receptor binding
(GO:0043125)
Erbb2-egfr signaling pathway
(GO:0038134)
Erbb2-erbb3 signaling pathway
(GO:0038133)
Erbb2-erbb4 signaling pathway
(GO:0038135)
Erbb3:erbb2 complex
(GO:0038143)
Estrous cycle
(GO:0044849)
Glial cell differentiation
(GO:0010001)
Growth factor binding
(GO:0019838)
Heart development
(GO:0007507)
Hsp90 protein binding
(GO:0051879)
Identical protein binding
(GO:0042802)
Immature t cell proliferation in thymus
(GO:0033080)
Intracellular signal transduction
(GO:0035556)
Liver development
(GO:0001889)
Mammary gland involution
(GO:0060056)
Microvillus
(GO:0005902)
Motor neuron axon guidance
(GO:0008045)
Multicellular organism development
(GO:0007275)
Myelination
(GO:0042552)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of immature t cell proliferation in thymus
(GO:0033088)
Nervous system development
(GO:0007399)
Neurogenesis
(GO:0022008)
Neuromuscular junction
(GO:0031594)
Neuromuscular junction development
(GO:0007528)
Neuron differentiation
(GO:0030182)
Neurotransmitter receptor localization to postsynaptic specialization membrane
(GO:0099645)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Oligodendrocyte differentiation
(GO:0048709)
Peripheral nervous system development
(GO:0007422)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of kinase activity
(GO:0033674)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein targeting to membrane
(GO:0090314)
Positive regulation of ras protein signal transduction
(GO:0046579)
Positive regulation of rho protein signal transduction
(GO:0035025)
Positive regulation of transcription by rna polymerase i
(GO:0045943)
Positive regulation of translation
(GO:0045727)
Presynaptic membrane
(GO:0042734)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein tyrosine kinase activity
(GO:0004713)
Receptor tyrosine kinase binding
(GO:0030971)
Regulation of cell differentiation
(GO:0045595)
Regulation of cell population proliferation
(GO:0042127)
Regulation of erk1 and erk2 cascade
(GO:0070372)
Regulation of microtubule-based process
(GO:0032886)
Response to axon injury
(GO:0048678)
Response to progesterone
(GO:0032570)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase i core binding
(GO:0001042)
Ruffle membrane
(GO:0032587)
Schwann cell development
(GO:0014044)
Semaphorin-plexin signaling pathway
(GO:0071526)
Semaphorin receptor complex
(GO:0002116)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Skeletal muscle tissue development
(GO:0007519)
Sympathetic nervous system development
(GO:0048485)
Tongue development
(GO:0043586)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Transmembrane signaling receptor activity
(GO:0004888)
Ubiquitin protein ligase binding
(GO:0031625)
Wound healing
(GO:0042060)

Other Information

Proteins

Q8K3F9_RAT

Genular Protein ID: 2757012195

Symbol: Q8K3F9_RAT

Name: N/A

UniProtKB Accession Codes:

Q8K3F9

Database IDs:

Citations:

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

Sequence Information:

Length: 1259
Mass: 139103
Checksum: B724BD5CC33AE953
Sequence:

MIIMELAAWC RWGFLLALLP PGIAGTQVCT GTDMKLRLPA SPETHLDMLR HLYQGCQVVQ 
GNLELTYVPA NASLSFLQDI QEVQGYMLIA HNQVKRVPLQ RLRIVRGTQL FEDKYALAVL 
DNRDPQDNVA ASTPGRTPEG LRELQLRSLT EILKGGVLIR GNPQLCYQDM VLWKDVFRKN 
NQLAPVDIDT NRSRACPPCA PACKDNHCWG ESPEDCQILT GTICTSGCAR CKGRLPTDCC 
HEQCAAGCTG PKHSDCLACL HFNHSGICEL HCPALVTYNT DTFESMHNPE GRYTFGASCV 
TTCPYNYLST EVGSCTLVCP PNNQEVTAED GTQRCEKCSK PCARVCYGLG MEHLRGARAI 
TSDNVQEFDG CKKIFGSLAF LPESFDGDPS SGIAPLRPEQ LQVFETLEEI TGYLYISAWP 
DSLRDLSVFQ NLRIIRGRIL HDGAYSLTLQ GLGIHSLGLR SLRELGSGLA LIHRNAHLCF 
VHTVPWDQLF RNPHQALLHS GNRPEEDCGL EGLVCNSLCA HGHCWGPGPT QCVNCSHFLR 
GQECVEECRV WKGLPREYVS DKRCLPCHPE CQPQNSSETC FGSEADQCAA CAHYKDSSSC 
VARCPSGVKP DLSYMPIWKY PDEEGICQPC PINCTHSCVD LDERGCPAEQ RASPVTFIIA 
TVVGVLLFLI LVVVVGILIK RRRQKIRKYT MRRLLQETEL VEPLTPSGAM PNQAQMRILK 
ETELRKVKVL GSGAFGTVYK GIWIPDGENV KIPVAIKVLR ENTSPKANKE ILDEAYVMAG 
VGSPYVSRLL GICLTSTVQL VTQLMPYGCL LDHVREHRGR LGSQDLLNWC VQIAKGMSYL 
EDVRLVHRDL AARNVLVKSP NHVKITDFGL ARLLDIDETE YHADGGKVPI KWMALESILR 
RRFTHQSDVW SYGVTVWELM TFGAKPYDGI PAREIPDLLE KGERLPQPPI CTIDVYMIMV 
KCWMIDSECR PRFRELVSEF SRMARDPQRF VVIQNEDLGP SSPMDSTFYR SLLEDDDMGD 
LVDAEEYLVP QQGFFSPDPT PGTGSTAHRR HRSSSTRSGG GELTLGLEPS EEGPPRSPLA 
PSEGAGSDVF DGDLAMGVTK GLQSLSPHDL SPLQRYSEDP TLPLPPETDG YVAPLACSPQ 
PEYVNQSEVQ PQPPLTPEGP LPPVRPAGAT LERPKTLSPG KNGVVKDVFA FGGAVENPEY 
LVPREGTASP PHPSPAFSPA FDNLYYWDQN SSEQGPPPSN FEGTPTAENP EYLGLDVPV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Erbb2

Associated with

Other Information

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Database document:

PubMed ID: 22673903