Genular: Defining Cellular Identity and Function

Details for: Fabp1

Gene ID: 24360

Symbol: Fabp1

Ensembl ID: ENSRNOG00000006675

Description: fatty acid binding protein 1

Associated with

Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to chemical stress
(R-RNO-9711123)
Cytoprotection by hmox1
(R-RNO-9707564)
Heme degradation
(R-RNO-189483)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of porphyrins
(R-RNO-189445)
Regulation of lipid metabolism by pparalpha
(R-RNO-400206)
Triglyceride catabolism
(R-RNO-163560)
Triglyceride metabolism
(R-RNO-8979227)
Antioxidant activity
(GO:0016209)
Apical cortex
(GO:0045179)
Bile acid binding
(GO:0032052)
Cellular oxidant detoxification
(GO:0098869)
Cellular response to hydrogen peroxide
(GO:0070301)
Cellular response to hypoxia
(GO:0071456)
Chromatin binding
(GO:0003682)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Fatty acid binding
(GO:0005504)
Fatty acid transport
(GO:0015908)
Heterocyclic compound binding
(GO:1901363)
Intestinal absorption
(GO:0050892)
Long-chain fatty acid transport
(GO:0015909)
Long-chain fatty acid transporter activity
(GO:0005324)
Lysophospholipid:sodium symporter activity
(GO:0051978)
Lysophospholipid transport
(GO:0051977)
Negative regulation of apoptotic process
(GO:0043066)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Oleic acid binding
(GO:0070538)
Peroxisomal matrix
(GO:0005782)
Phospholipid binding
(GO:0005543)
Positive regulation of fatty acid beta-oxidation
(GO:0032000)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Response to vitamin b3
(GO:0033552)

Other Information

Proteins

Fatty acid-binding protein, liver

Genular Protein ID: 494185715

Symbol: FABPL_RAT

Name: Fatty acid-binding protein, liver

UniProtKB Accession Codes:

P02692

Database IDs:

Citations:

PubMed ID: 7084456

Title: Primary structure of rat liver Z-protein. A low-Mr cytosol protein that binds sterols, fatty acids and other small molecules.

PubMed ID: 7084456

DOI: 10.1016/0014-5793(82)80521-8

PubMed ID: 6641731

Title: Isolation and characterization of the three fractions (DE-I, DE-II and DE-III) of rat-liver Z-protein and the complete primary structure of DE-II.

PubMed ID: 6641731

DOI: 10.1111/j.1432-1033.1983.tb07781.x

PubMed ID: 6298233

Title: The nucleotide sequence of rat liver fatty acid binding protein mRNA.

PubMed ID: 6298233

DOI: 10.1016/s0021-9258(18)32868-0

PubMed ID: 3007511

Title: The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands.

PubMed ID: 3007511

DOI: 10.1016/s0021-9258(19)57250-7

PubMed ID: 3840724

Title: Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques.

PubMed ID: 3840724

DOI: 10.1016/0009-3084(85)90063-5

PubMed ID: 1898328

Title: Synthesis of a gene for rat liver fatty-acid-binding protein and its expression in Escherichia coli.

PubMed ID: 1898328

DOI: 10.1042/bj2780365

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3478711

Title: Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes.

PubMed ID: 3478711

DOI: 10.1073/pnas.84.21.7547

PubMed ID: 3838749

Title: Translational control of the circadian rhythm of liver sterol carrier protein. Analysis of mRNA sequences with a specific cDNA probe.

PubMed ID: 3838749

DOI: 10.1016/s0021-9258(18)89041-x

PubMed ID: 1939124

Title: Identification by photoaffinity labeling of fatty acid-binding protein as a potential warfarin receptor in rat liver.

PubMed ID: 1939124

DOI: 10.1016/s0021-9258(18)54769-4

PubMed ID: 8117116

Title: On the molecular origin of charge heterogeneity of rat liver fatty acid-binding protein (Z-protein).

PubMed ID: 8117116

DOI: 10.1006/abbi.1994.1088

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 25732850

Title: Human FABP1 T94A variant enhances cholesterol uptake.

PubMed ID: 25732850

DOI: 10.1016/j.bbalip.2015.02.015

PubMed ID: 9054409

Title: The crystal structure of the liver fatty acid-binding protein. A complex with two bound oleates.

PubMed ID: 9054409

DOI: 10.1074/jbc.272.11.7140

PubMed ID: 17927211

Title: Solution-state molecular structure of apo and oleate-liganded liver fatty acid-binding protein.

PubMed ID: 17927211

DOI: 10.1021/bi701092r

Sequence Information:

Length: 127
Mass: 14273
Checksum: 08C7F59A99FE0D3A
Sequence:

MNFSGKYQVQ SQENFEPFMK AMGLPEDLIQ KGKDIKGVSE IVHEGKKVKL TITYGSKVIH 
NEFTLGEECE LETMTGEKVK AVVKMEGDNK MVTTFKGIKS VTEFNGDTIT NTMTLGDIVY 
KRVSKRI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fabp1

Associated with

Other Information

Primary structure of rat liver Z-protein. A low-Mr cytosol protein that binds sterols, fatty acids and other small molecules. PubMed ID: 7084456

Isolation and characterization of the three fractions (DE-I, DE-II and DE-III) of rat-liver Z-protein and the complete primary structure of DE-II. PubMed ID: 6641731

The nucleotide sequence of rat liver fatty acid binding protein mRNA. PubMed ID: 6298233

The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands. PubMed ID: 3007511

Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques. PubMed ID: 3840724

Synthesis of a gene for rat liver fatty-acid-binding protein and its expression in Escherichia coli. PubMed ID: 1898328

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes. PubMed ID: 3478711

Translational control of the circadian rhythm of liver sterol carrier protein. Analysis of mRNA sequences with a specific cDNA probe. PubMed ID: 3838749

Identification by photoaffinity labeling of fatty acid-binding protein as a potential warfarin receptor in rat liver. PubMed ID: 1939124

On the molecular origin of charge heterogeneity of rat liver fatty acid-binding protein (Z-protein). PubMed ID: 8117116

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Human FABP1 T94A variant enhances cholesterol uptake. PubMed ID: 25732850

The crystal structure of the liver fatty acid-binding protein. A complex with two bound oleates. PubMed ID: 9054409

Solution-state molecular structure of apo and oleate-liganded liver fatty acid-binding protein. PubMed ID: 17927211