Genular: Defining Cellular Identity and Function

Details for: Fbp1

Gene ID: 24362

Symbol: Fbp1

Ensembl ID: ENSRNOG00000017597

Description: fructose-bisphosphatase 1

Associated with

Glucose metabolism
(R-RNO-70326)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Amp binding
(GO:0016208)
Cellular hyperosmotic salinity response
(GO:0071475)
Cellular hypotonic salinity response
(GO:0071477)
Cellular response to camp
(GO:0071320)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to magnesium ion
(GO:0071286)
Cellular response to phorbol 13-acetate 12-myristate
(GO:1904628)
Cellular response to raffinose
(GO:0097403)
Cellular response to xenobiotic stimulus
(GO:0071466)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dephosphorylation
(GO:0016311)
Extracellular space
(GO:0005615)
Fructose 1,6-bisphosphate 1-phosphatase activity
(GO:0042132)
Fructose 1,6-bisphosphate metabolic process
(GO:0030388)
Fructose 6-phosphate metabolic process
(GO:0006002)
Fructose metabolic process
(GO:0006000)
Gluconeogenesis
(GO:0006094)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Monosaccharide binding
(GO:0048029)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of glycolytic process
(GO:0045820)
Negative regulation of ras protein signal transduction
(GO:0046580)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Regulation of gluconeogenesis
(GO:0006111)
Response to nutrient levels
(GO:0031667)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Sucrose biosynthetic process
(GO:0005986)

Other Information

Proteins

Fructose-1,6-bisphosphatase 1

Genular Protein ID: 138332653

Symbol: F16P1_RAT

Name: Fructose-1,6-bisphosphatase 1

UniProtKB Accession Codes:

P19112 Q64594

Database IDs:

Citations:

PubMed ID: 2847161

Title: cDNA sequence of rat liver fructose-1,6-bisphosphatase and evidence for down-regulation of its mRNA by insulin.

PubMed ID: 2847161

DOI: 10.1073/pnas.85.22.8430

PubMed ID: 1846613

Title: The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression.

PubMed ID: 1846613

DOI: 10.1016/s0021-9258(18)52217-1

PubMed ID: 7589895

Title: Liver fructose-1,6-bisphosphatase cDNA: trans-complementation of fission yeast and characterization of two human transcripts.

PubMed ID: 7589895

DOI: 10.1046/j.1432-0436.1995.5910051.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6305949

Title: Amino acid sequence of the COOH-terminal region of fructose-1,6-bisphosphatases in relation to cyclic AMP-dependent phosphorylation.

PubMed ID: 6305949

DOI: 10.1016/s0021-9258(18)32228-2

PubMed ID: 1313010

Title: Lysine 274 is essential for fructose 2,6-bisphosphate inhibition of fructose-1,6-bisphosphatase.

PubMed ID: 1313010

DOI: 10.1016/s0021-9258(19)50459-8

PubMed ID: 19651254

Title: Identification of novel protein targets regulated by maternal dietary fatty acid composition in neonatal rat liver.

PubMed ID: 19651254

DOI: 10.1016/j.jprot.2009.07.008

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 363
Mass: 39609
Checksum: 0470F1A2EA917D6F
Sequence:

MVDHAPFETD ISTLTRFVLE EGRKAGGTGE MTQLLNSLCT AIKAISSAVR QAGIAQLYGI 
AGSTNVTGDQ VKKLDILSND LVINMLKSSY ATCVLVSEED THAIIIEPEK RGKYVVCFDP 
LDGSSNIDCL ASIGTIFGIY RKTSANEPSE KDALQPGRNL VAAGYALYGS ATMLVLAMNC 
GVNCFMLDPS IGEFILVDRD VKIKKKGNIY SINEGYAKDF DPAINEYIQR KKFPPDNSAP 
YGARYVGSMV ADVHRTLVYG GIFLYPANKK NPSGKLRLLY ECNPIAYVME KAGGLATTGN 
EDILDIVPTE IHQKAPVIMG STEDVQEFLE IYNKDKAKSR PSLPLPQSRA RESPVHSICD 
ELF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fbp1

Associated with

Other Information

cDNA sequence of rat liver fructose-1,6-bisphosphatase and evidence for down-regulation of its mRNA by insulin. PubMed ID: 2847161

The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression. PubMed ID: 1846613

Liver fructose-1,6-bisphosphatase cDNA: trans-complementation of fission yeast and characterization of two human transcripts. PubMed ID: 7589895

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Amino acid sequence of the COOH-terminal region of fructose-1,6-bisphosphatases in relation to cyclic AMP-dependent phosphorylation. PubMed ID: 6305949

Lysine 274 is essential for fructose 2,6-bisphosphate inhibition of fructose-1,6-bisphosphatase. PubMed ID: 1313010

Identification of novel protein targets regulated by maternal dietary fatty acid composition in neonatal rat liver. PubMed ID: 19651254

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903