Genular: Defining Cellular Identity and Function

Details for: Fgb

Gene ID: 24366

Symbol: Fgb

Ensembl ID: ENSRNOG00000007092

Description: fibrinogen beta chain

Associated with

Common pathway of fibrin clot formation
(R-RNO-140875)
Extracellular matrix organization
(R-RNO-1474244)
Formation of fibrin clot (clotting cascade)
(R-RNO-140877)
Grb2:sos provides linkage to mapk signaling for integrins
(R-RNO-354194)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Integrin cell surface interactions
(R-RNO-216083)
Integrin signaling
(R-RNO-354192)
Map2k and mapk activation
(R-RNO-5674135)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
P130cas linkage to mapk signaling for integrins
(R-RNO-372708)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet aggregation (plug formation)
(R-RNO-76009)
Platelet degranulation
(R-RNO-114608)
Raf/map kinase cascade
(R-RNO-5673001)
Regulation of tlr by endogenous ligand
(R-RNO-5686938)
Response to elevated platelet cytosolic ca2+
(R-RNO-76005)
Signal transduction
(R-RNO-162582)
Toll-like receptor cascades
(R-RNO-168898)
Adaptive immune response
(GO:0002250)
Blood coagulation, fibrin clot formation
(GO:0072378)
Blood microparticle
(GO:0072562)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion molecule binding
(GO:0050839)
Cell cortex
(GO:0005938)
Cell surface
(GO:0009986)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to leptin stimulus
(GO:0044320)
Collagen-containing extracellular matrix
(GO:0062023)
Endoplasmic reticulum
(GO:0005783)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Fibrinogen complex
(GO:0005577)
Fibrinolysis
(GO:0042730)
Induction of bacterial agglutination
(GO:0043152)
Innate immune response
(GO:0045087)
Negative regulation of endothelial cell apoptotic process
(GO:2000352)
Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
(GO:1902042)
Plasminogen activation
(GO:0031639)
Platelet activation
(GO:0030168)
Platelet aggregation
(GO:0070527)
Platelet alpha granule
(GO:0031091)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of exocytosis
(GO:0045921)
Positive regulation of heterotypic cell-cell adhesion
(GO:0034116)
Positive regulation of peptide hormone secretion
(GO:0090277)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of vasoconstriction
(GO:0045907)
Protein-containing complex assembly
(GO:0065003)
Protein-folding chaperone binding
(GO:0051087)
Protein polymerization
(GO:0051258)
Response to calcium ion
(GO:0051592)
Signaling receptor binding
(GO:0005102)
Structural molecule activity
(GO:0005198)
Synapse
(GO:0045202)

Other Information

Proteins

Fibrinogen beta chain

Genular Protein ID: 2759541875

Symbol: FIBB_RAT

Name: Fibrinogen beta chain

UniProtKB Accession Codes:

P14480 Q5I0P7 Q7TME5

Database IDs:

Citations:

PubMed ID: 7841303

Title: Cloning of the complete coding sequence of rat fibrinogen B beta chain cDNA: interspecies conservation of fibrin beta 15-42 primary structure.

PubMed ID: 7841303

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6232608

Title: Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions.

PubMed ID: 6232608

DOI: 10.1073/pnas.81.8.2313

PubMed ID: 2673932

Title: Cloning and characterization of a cDNA for the B beta chain of rat fibrinogen: evolutionary conservation of translated and 3'-untranslated sequences.

PubMed ID: 2673932

DOI: 10.1016/0378-1119(89)90100-5

PubMed ID: 3817019

Title: Molecular cloning of mRNA sequences transiently induced during rat liver regeneration.

PubMed ID: 3817019

DOI: 10.1016/0014-4827(87)90223-0

Sequence Information:

Length: 479
Mass: 54235
Checksum: 810698D9A65D0DE7
Sequence:

MRHLWLLLLS VSLVQTQAAT TDSDKVDLSI ARGHRPVDRR KEEPPSLRPA PPPISGGGYR 
ARPAKVDAGQ KKVERKPPDA GGCVHGDGDM GVLCPTGCEL RQTLLNHERP IKNSIAELNS 
NINSVSETSS VTFQYLTLLK DMWKKKQAQV KDNENVINEY SSILEDQKLY IDETVNDNIP 
LNLRVLRSIL EDLRSKIQKL ESDISAQTEY CHTPCTVNCN IPVVSGKECE EIIRKGGETS 
EMYLIQPDTS SKPYRVYCDM KTENGGWTVI QNRQDGSVDF GRKWDPYKKG FGNIATNEDT 
KKYCGLPGEY WLGNDKISQL TRIGPTELLI EMEDWKGDKV KAHYGGFTVQ TEANKYQVSV 
NKYKGTAGNA LMEGASQLVG ENRTMTIHNG MFFSTYDRDN DGWVTTDPRK QCSKEDGGGW 
WYNRCHAANP NGRYYWGGLY SWDMSKHGTD DGVVWMNWKG SWYSMRRMSM KIRPVFPQQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgb

Associated with

Other Information

Cloning of the complete coding sequence of rat fibrinogen B beta chain cDNA: interspecies conservation of fibrin beta 15-42 primary structure. PubMed ID: 7841303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions. PubMed ID: 6232608