Genular: Defining Cellular Identity and Function

Details for: Gfap

Gene ID: 24387

Symbol: Gfap

Ensembl ID: ENSRNOG00000002919

Description: glial fibrillary acidic protein

Associated with

Astrocyte development
(GO:0014002)
Astrocyte end-foot
(GO:0097450)
Astrocyte projection
(GO:0097449)
Bergmann glial cell differentiation
(GO:0060020)
Cell body
(GO:0044297)
Cell projection
(GO:0042995)
Cytoplasm
(GO:0005737)
Cytoplasmic side of lysosomal membrane
(GO:0098574)
Cytoskeleton
(GO:0005856)
D-aspartate import across plasma membrane
(GO:0070779)
Extracellular matrix organization
(GO:0030198)
Gene expression
(GO:0010467)
Glial cell projection
(GO:0097386)
Identical protein binding
(GO:0042802)
Integrin binding
(GO:0005178)
Intermediate filament
(GO:0005882)
Intermediate filament-based process
(GO:0045103)
Intermediate filament cytoskeleton
(GO:0045111)
Intermediate filament organization
(GO:0045109)
Intracellular protein transport
(GO:0006886)
Kinase binding
(GO:0019900)
Long-term synaptic potentiation
(GO:0060291)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Negative regulation of neuron projection development
(GO:0010977)
Neuron projection development
(GO:0031175)
Neuron projection regeneration
(GO:0031102)
Positive regulation of glial cell proliferation
(GO:0060252)
Positive regulation of schwann cell proliferation
(GO:0010625)
Protein binding
(GO:0005515)
Regulation of chaperone-mediated autophagy
(GO:1904714)
Regulation of neurotransmitter uptake
(GO:0051580)
Schwann cell proliferation
(GO:0014010)
Structural constituent of cytoskeleton
(GO:0005200)

Other Information

Proteins

Glial fibrillary acidic protein

Genular Protein ID: 296303596

Symbol: GFAP_RAT

Name: Glial fibrillary acidic protein

UniProtKB Accession Codes:

P47819 A7REI0 Q7TQ31 Q9R1Q3 Q9Z2S0

Database IDs:

Citations:

PubMed ID: 1629938

Title: Isolation of cDNA clones encoding rat glial fibrillary acidic protein: expression in astrocytes and in Schwann cells.

PubMed ID: 1629938

DOI: 10.1002/jnr.490320102

PubMed ID: 10336251

Title: Structural features of the rat GFAP gene and identification of a novel alternative transcript.

PubMed ID: 10336251

DOI: 10.1002/(sici)1097-4547(19990501)56:3<219::aid-jnr1>3.0.co;2-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7897704

Title: Tissue-specific DNA methylation patterns of the rat glial fibrillary acidic protein gene.

PubMed ID: 7897704

DOI: 10.1002/jnr.490390610

PubMed ID: 17203480

Title: Identification and characterization of GFAPkappa, a novel glial fibrillary acidic protein isoform.

PubMed ID: 17203480

DOI: 10.1002/glia.20475

PubMed ID: 12837269

Title: Genetic polymorphism and sequence evolution of an alternatively spliced exon of the glial fibrillary acidic protein gene, GFAP.

PubMed ID: 12837269

DOI: 10.1016/s0888-7543(03)00106-x

PubMed ID: 2153890

Title: Messenger RNA for glial fibrillary acidic protein is decreased in rat brain following acute and chronic corticosterone treatment.

PubMed ID: 2153890

DOI: 10.1016/0169-328x(90)90066-m

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 430
Mass: 49957
Checksum: 6437A1F784E37D1A
Sequence:

MERRRITSAR RSYASSETMV RGHGPTRHLG TIPRLSLSRM TPPLPARVDF SLAGALNAGF 
KETRASERAE MMELNDRFAS YIEKVRFLEQ QNKALAAELN QLRAKEPTKL ADVYQAELRE 
LRLRLDQLTT NSARLEVERD NLTQDLGTLR QKLQDETNLR LEAENNLAVY RQEADEATLA 
RVDLERKVES LEEEIQFLRK IHEEEVRELQ EQLAQQQVHV EMDVAKPDLT AALREIRTQY 
EAVATSNMQE TEEWYRSKFA DLTDVASRNA ELLRQAKHEA NDYRRQLQAL TCDLESLRGT 
NESLERQMRE QEERHARESA SYQEALARLE EEGQSLKEEM ARHLQEYQDL LNVKLALDIE 
IATYRKLLEG EENRITIPVQ TFSNLQIRET SLDTKSVSEG HLKRNIVVKT VEMRDGEVIK 
ESKQEHKDVM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gfap

Associated with

Other Information

Isolation of cDNA clones encoding rat glial fibrillary acidic protein: expression in astrocytes and in Schwann cells. PubMed ID: 1629938

Structural features of the rat GFAP gene and identification of a novel alternative transcript. PubMed ID: 10336251

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Tissue-specific DNA methylation patterns of the rat glial fibrillary acidic protein gene. PubMed ID: 7897704

Identification and characterization of GFAPkappa, a novel glial fibrillary acidic protein isoform. PubMed ID: 17203480

Genetic polymorphism and sequence evolution of an alternatively spliced exon of the glial fibrillary acidic protein gene, GFAP. PubMed ID: 12837269

Messenger RNA for glial fibrillary acidic protein is decreased in rat brain following acute and chronic corticosterone treatment. PubMed ID: 2153890

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903