Genular: Defining Cellular Identity and Function

Details for: Grm2

Gene ID: 24415

Symbol: Grm2

Ensembl ID: ENSRNOG00000013171

Description: glutamate metabotropic receptor 2

Associated with

Class c/3 (metabotropic glutamate/pheromone receptors)
(R-RNO-420499)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-inhibiting g protein-coupled glutamate receptor signaling pathway
(GO:0007196)
Astrocyte projection
(GO:0097449)
Axon
(GO:0030424)
Behavioral response to nicotine
(GO:0035095)
Calcium channel regulator activity
(GO:0005246)
Dendrite
(GO:0030425)
Gene expression
(GO:0010467)
Glutamate receptor signaling pathway
(GO:0007215)
Glutamatergic synapse
(GO:0098978)
Glutamate secretion
(GO:0014047)
G protein-coupled glutamate receptor signaling pathway
(GO:0007216)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Group ii metabotropic glutamate receptor activity
(GO:0001641)
Intracellular glutamate homeostasis
(GO:0090461)
Long-term synaptic depression
(GO:0060292)
Neuron projection
(GO:0043005)
Plasma membrane
(GO:0005886)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Regulation of dopamine secretion
(GO:0014059)
Regulation of glutamate secretion
(GO:0014048)
Regulation of neurotransmitter secretion
(GO:0046928)
Regulation of response to drug
(GO:2001023)
Regulation of synaptic transmission, glutamatergic
(GO:0051966)
Response to cocaine
(GO:0042220)
Scaffold protein binding
(GO:0097110)

Other Information

Proteins

Metabotropic glutamate receptor 2

Genular Protein ID: 1010733670

Symbol: GRM2_RAT

Name: Metabotropic glutamate receptor 2

UniProtKB Accession Codes:

P31421

Database IDs:

Citations:

PubMed ID: 1309649

Title: A family of metabotropic glutamate receptors.

PubMed ID: 1309649

DOI: 10.1016/0896-6273(92)90118-w

PubMed ID: 11850456

Title: Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.

PubMed ID: 11850456

DOI: 10.1523/jneurosci.22-04-01280.2002

Sequence Information:

Length: 872
Mass: 95774
Checksum: 1E74CABD6AD4BED9
Sequence:

MESLLGFLAL LLLWGAVAEG PAKKVLTLEG DLVLGGLFPV HQKGGPAEEC GPVNEHRGIQ 
RLEAMLFALD RINRDPHLLP GVRLGAHILD SCSKDTHALE QALDFVRASL SRGADGSRHI 
CPDGSYATHS DAPTAVTGVI GGSYSDVSIQ VANLLRLFQI PQISYASTSA KLSDKSRYDY 
FARTVPPDFF QAKAMAEILR FFNWTYVSTV ASEGDYGETG IEAFELEARA RNICVATSEK 
VGRAMSRAAF EGVVRALLQK PSARVAVLFT RSEDARELLA ATQRLNASFT WVASDGWGAL 
ESVVAGSERA AEGAITIELA SYPISDFASY FQSLDPWNNS RNPWFREFWE ERFHCSFRQR 
DCAAHSLRAV PFEQESKIMF VVNAVYAMAH ALHNMHRALC PNTTHLCDAM RPVNGRRLYK 
DFVLNVKFDA PFRPADTDDE VRFDRFGDGI GRYNIFTYLR AGSGRYRYQK VGYWAEGLTL 
DTSFIPWASP SAGPLPASRC SEPCLQNEVK SVQPGEVCCW LCIPCQPYEY RLDEFTCADC 
GLGYWPNASL TGCFELPQEY IRWGDAWAVG PVTIACLGAL ATLFVLGVFV RHNATPVVKA 
SGRELCYILL GGVFLCYCMT FVFIAKPSTA VCTLRRLGLG TAFSVCYSAL LTKTNRIARI 
FGGAREGAQR PRFISPASQV AICLALISGQ LLIVAAWLVV EAPGTGKETA PERREVVTLR 
CNHRDASMLG SLAYNVLLIA LCTLYAFKTR KCPENFNEAK FIGFTMYTTC IIWLAFLPIF 
YVTSSDYRVQ TTTMCVSVSL SGSVVLGCLF APKLHIILFQ PQKNVVSHRA PTSRFGSAAP 
RASANLGQGS GSQFVPTVCN GREVVDSTTS SL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.