Genular: Defining Cellular Identity and Function

Details for: Grm4

Gene ID: 24417

Symbol: Grm4

Ensembl ID: ENSRNOG00000000487

Description: glutamate metabotropic receptor 4

Associated with

Class c/3 (metabotropic glutamate/pheromone receptors)
(R-RNO-420499)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adenylate cyclase-inhibiting g protein-coupled glutamate receptor signaling pathway
(GO:0007196)
Adenylate cyclase inhibiting g protein-coupled glutamate receptor activity
(GO:0001640)
Calcium-dependent protein binding
(GO:0048306)
Calmodulin binding
(GO:0005516)
Cerebellar granule cell to purkinje cell synapse
(GO:0150048)
Chemical synaptic transmission
(GO:0007268)
Cytoplasmic vesicle
(GO:0031410)
Dendritic shaft
(GO:0043198)
Gamma-aminobutyric acid secretion
(GO:0014051)
Glutamate receptor activity
(GO:0008066)
Glutamatergic synapse
(GO:0098978)
G protein-coupled glutamate receptor signaling pathway
(GO:0007216)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Learning
(GO:0007612)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of synaptic transmission
(GO:0050805)
Neuron projection
(GO:0043005)
Neuron projection development
(GO:0031175)
Parallel fiber to purkinje cell synapse
(GO:0098688)
Plasma membrane
(GO:0005886)
Positive regulation of mapk cascade
(GO:0043410)
Presynaptic active zone membrane
(GO:0048787)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Regulation of neuron apoptotic process
(GO:0043523)
Regulation of synaptic transmission, glutamatergic
(GO:0051966)
Synaptic transmission, gabaergic
(GO:0051932)
Synaptic transmission, glutamatergic
(GO:0035249)
Terminal bouton
(GO:0043195)

Other Information

Proteins

Metabotropic glutamate receptor 4

Genular Protein ID: 1779304661

Symbol: GRM4_RAT

Name: Metabotropic glutamate receptor 4

UniProtKB Accession Codes:

P31423

Database IDs:

Citations:

PubMed ID: 1309649

Title: A family of metabotropic glutamate receptors.

PubMed ID: 1309649

DOI: 10.1016/0896-6273(92)90118-w

PubMed ID: 8338667

Title: The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins.

PubMed ID: 8338667

DOI: 10.1016/0896-6273(93)90269-w

PubMed ID: 11122333

Title: Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1.

PubMed ID: 11122333

DOI: 10.1046/j.1460-9568.2000.01309.x

Sequence Information:

Length: 912
Mass: 101819
Checksum: 336430EF19B4B577
Sequence:

MSGKGGWAWW WARLPLCLLL SLYAPWVPSS LGKPKGHPHM NSIRIDGDIT LGGLFPVHGR 
GSEGKACGEL KKEKGIHRLE AMLFALDRIN NDPDLLPNIT LGARILDTCS RDTHALEQSL 
TFVQALIEKD GTEVRCGSGG PPIITKPERV VGVIGASGSS VSIMVANILR LFKIPQISYA 
STAPDLSDNS RYDFFSRVVP SDTYQAQAMV DIVRALKWNY VSTLASEGSY GESGVEAFIQ 
KSRENGGVCI AQSVKIPREP KTGEFDKIIK RLLETSNARG IIIFANEDDI RRVLEAARRA 
NQTGHFFWMG SDSWGSKSAP VLRLEEVAEG AVTILPKRMS VRGFDRYFSS RTLDNNRRNI 
WFAEFWEDNF HCKLSRHALK KGSHIKKCTN RERIGQDSAY EQEGKVQFVI DAVYAMGHAL 
HAMHRDLCPG RVGLCPRMDP VDGTQLLKYI RNVNFSGIAG NPVTFNENGD APGRYDIYQY 
QLRNGSAEYK VIGSWTDHLH LRIERMQWPG SGQQLPRSIC SLPCQPGERK KTVKGMACCW 
HCEPCTGYQY QVDRYTCKTC PYDMRPTENR TSCQPIPIVK LEWDSPWAVL PLFLAVVGIA 
ATLFVVVTFV RYNDTPIVKA SGRELSYVLL AGIFLCYATT FLMIAEPDLG TCSLRRIFLG 
LGMSISYAAL LTKTNRIYRI FEQGKRSVSA PRFISPASQL AITFILISLQ LLGICVWFVV 
DPSHSVVDFQ DQRTLDPRFA RGVLKCDISD LSLICLLGYS MLLMVTCTVY AIKTRGVPET 
FNEAKPIGFT MYTTCIVWLA FIPIFFGTSQ SADKLYIQTT TLTVSVSLSA SVSLGMLYMP 
KVYIILFHPE QNVPKRKRSL KAVVTAATMS NKFTQKGNFR PNGEAKSELC ENLETPALAT 
KQTYVTYTNH AI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.