Genular: Defining Cellular Identity and Function

Details for: Gstp1

Gene ID: 24426

Symbol: Gstp1

Ensembl ID: ENSRNOG00000018237

Description: glutathione S-transferase pi 1

Associated with

Biological oxidations
(R-RNO-211859)
Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to chemical stress
(R-RNO-9711123)
Detoxification of reactive oxygen species
(R-RNO-3299685)
Drug adme
(R-RNO-9748784)
Glutathione conjugation
(R-RNO-156590)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Metabolism
(R-RNO-1430728)
Neutrophil degranulation
(R-RNO-6798695)
Paracetamol adme
(R-RNO-9753281)
Phase ii - conjugation of compounds
(R-RNO-156580)
Animal organ regeneration
(GO:0031100)
Cellular oxidant detoxification
(GO:0098869)
Cellular response to cell-matrix adhesion
(GO:0071460)
Cellular response to epidermal growth factor stimulus
(GO:0071364)
Cellular response to glucocorticoid stimulus
(GO:0071385)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to lipopolysaccharide
(GO:0071222)
Common myeloid progenitor cell proliferation
(GO:0035726)
Cytosol
(GO:0005829)
Dinitrosyl-iron complex binding
(GO:0035731)
Fatty acid binding
(GO:0005504)
Glutathione derivative biosynthetic process
(GO:1901687)
Glutathione metabolic process
(GO:0006749)
Glutathione peroxidase activity
(GO:0004602)
Glutathione transferase activity
(GO:0004364)
Hepoxilin biosynthetic process
(GO:0051122)
Jun kinase binding
(GO:0008432)
Kinase regulator activity
(GO:0019207)
Linoleic acid metabolic process
(GO:0043651)
Mitochondrion
(GO:0005739)
Negative regulation of biosynthetic process
(GO:0009890)
Negative regulation of canonical nf-kappab signal transduction
(GO:0043124)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of extrinsic apoptotic signaling pathway
(GO:2001237)
Negative regulation of fibroblast proliferation
(GO:0048147)
Negative regulation of interleukin-1 beta production
(GO:0032691)
Negative regulation of leukocyte proliferation
(GO:0070664)
Negative regulation of monocyte chemotactic protein-1 production
(GO:0071638)
Negative regulation of nitric-oxide synthase biosynthetic process
(GO:0051771)
Negative regulation of smooth muscle cell chemotaxis
(GO:0071672)
Negative regulation of stress-activated mapk cascade
(GO:0032873)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Nucleus
(GO:0005634)
Oligodendrocyte development
(GO:0014003)
Organic cyclic compound binding
(GO:0097159)
Positive regulation of superoxide anion generation
(GO:0032930)
Prostaglandin metabolic process
(GO:0006693)
Protein-containing complex
(GO:0032991)
Protein kinase binding
(GO:0019901)
Regulation of erk1 and erk2 cascade
(GO:0070372)
Regulation of stress-activated mapk cascade
(GO:0032872)
Response to amino acid
(GO:0043200)
Response to estradiol
(GO:0032355)
Response to ethanol
(GO:0045471)
Response to l-ascorbic acid
(GO:0033591)
Response to nutrient levels
(GO:0031667)
Response to reactive oxygen species
(GO:0000302)
Response to toxic substance
(GO:0009636)
S-nitrosoglutathione binding
(GO:0035730)
Toxic substance binding
(GO:0015643)
Traf2-gstp1 complex
(GO:0097057)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

Chain 7

Genular Protein ID: 2821069402

Symbol: GSTP1_RAT

Name: Chain 7

UniProtKB Accession Codes:

P04906

Database IDs:

Citations:

PubMed ID: 2995915

Title: Cloning and the nucleotide sequence of rat glutathione S-transferase P cDNA.

PubMed ID: 2995915

DOI: 10.1093/nar/13.17.6049

PubMed ID: 3029128

Title: The structure of the rat glutathione S-transferase P gene and related pseudogenes.

PubMed ID: 3029128

DOI: 10.1016/s0021-9258(18)61435-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3359441

Title: Purification and characterization of P-52 (glutathione S-transferase-P or 7-7) from normal liver and putative preneoplastic liver nodules.

PubMed ID: 3359441

PubMed ID: 3864155

Title: Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

PubMed ID: 3864155

DOI: 10.1073/pnas.82.21.7202

Sequence Information:

Length: 210
Mass: 23439
Checksum: 9B71785D1FC28FDB
Sequence:

MPPYTIVYFP VRGRCEATRM LLADQGQSWK EEVVTIDVWL QGSLKSTCLY GQLPKFEDGD 
LTLYQSNAIL RHLGRSLGLY GKDQKEAALV DMVNDGVEDL RCKYGTLIYT NYENGKDDYV 
KALPGHLKPF ETLLSQNQGG KAFIVGNQIS FADYNLLDLL LVHQVLAPGC LDNFPLLSAY 
VARLSARPKI KAFLSSPDHL NRPINGNGKQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gstp1

Associated with

Other Information

Cloning and the nucleotide sequence of rat glutathione S-transferase P cDNA. PubMed ID: 2995915

The structure of the rat glutathione S-transferase P gene and related pseudogenes. PubMed ID: 3029128

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334