Genular: Defining Cellular Identity and Function

Details for: Hp

Gene ID: 24464

Symbol: Hp

Ensembl ID: ENSRNOG00000014964

Description: haptoglobin

Associated with

Binding and uptake of ligands by scavenger receptors
(R-RNO-2173782)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Neutrophil degranulation
(R-RNO-6798695)
Scavenging of heme from plasma
(R-RNO-2168880)
Vesicle-mediated transport
(R-RNO-5653656)
Acute-phase response
(GO:0006953)
Animal organ regeneration
(GO:0031100)
Antioxidant activity
(GO:0016209)
Blood microparticle
(GO:0072562)
Cellular oxidant detoxification
(GO:0098869)
Defense response to bacterium
(GO:0042742)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Haptoglobin-hemoglobin complex
(GO:0031838)
Hemoglobin binding
(GO:0030492)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Liver development
(GO:0001889)
Negative regulation of hydrogen peroxide catabolic process
(GO:2000296)
Notch signaling pathway
(GO:0007219)
Proteolysis
(GO:0006508)
Response to bacterium
(GO:0009617)
Response to cobalamin
(GO:0033590)
Response to electrical stimulus
(GO:0051602)
Response to glucocorticoid
(GO:0051384)
Response to growth hormone
(GO:0060416)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to l-ascorbic acid
(GO:0033591)
Response to lead ion
(GO:0010288)
Response to lipopolysaccharide
(GO:0032496)
Response to magnesium ion
(GO:0032026)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to starvation
(GO:0042594)
Response to x-ray
(GO:0010165)
Response to xenobiotic stimulus
(GO:0009410)
Serine-type endopeptidase activity
(GO:0004252)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

Haptoglobin

Genular Protein ID: 770211686

Symbol: HPT_RAT

Name: Haptoglobin

UniProtKB Accession Codes:

P06866 Q5EBB4 Q7TP23

Database IDs:

Citations:

PubMed ID: 2320005

Title: Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene.

PubMed ID: 2320005

DOI: 10.1128/mcb.10.4.1573-1583.1990

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6204979

Title: Nucleotide sequence of rat haptoglobin cDNA. Characterization of the alpha beta-subunit junction region of prohaptoglobin.

PubMed ID: 6204979

DOI: 10.1016/s0021-9258(17)47287-5

PubMed ID: 6863267

Title: Biosynthesis and processing of rat haptoglobin.

PubMed ID: 6863267

DOI: 10.1016/s0021-9258(18)32258-0

PubMed ID: 975782

Title: Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin beta-chains.

PubMed ID: 975782

DOI: 10.1016/0305-0491(76)90320-5

Sequence Information:

Length: 347
Mass: 38563
Checksum: 9DF52389AFD755D6
Sequence:

MRALGAVVTL LLWGQLFAVE LGNDATDIED DSCPKPPEIA NGYVEHLVRY RCRQFYKLQT 
EGDGIYTLNS EKQWVNPAAG DKLPKCEAVC GKPKHPVDQV QRIIGGSMDA KGSFPWQAKM 
ISRHGLTTGA TLISDQWLLT TAQNLFLNHS ENATAKDIAP TLTLYVGKNQ LVEIEKVVLH 
PERSVVDIGL IKLKQKVLVT EKVMPICLPS KDYVAPGRMG YVSGWGRNVN FRFTERLKYV 
MLPVADQEKC ELHYEKSTVP EKKGAVSPVG VQPILNKHTF CAGLTKYEED TCYGDAGSAF 
AVHDTEEDTW YAAGILSFDK SCAVAEYGVY VRATDLKDWV QETMAKN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hp

Associated with

Other Information

Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene. PubMed ID: 2320005

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nucleotide sequence of rat haptoglobin cDNA. Characterization of the alpha beta-subunit junction region of prohaptoglobin. PubMed ID: 6204979