Genular: Defining Cellular Identity and Function

Details for: Hsd3b5

Gene ID: 24470

Symbol: Hsd3b5

Ensembl ID: ENSRNOG00000019417

Description: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

Associated with

Androgen biosynthesis
(R-RNO-193048)
Glucocorticoid biosynthesis
(R-RNO-194002)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroid hormones
(R-RNO-196071)
Metabolism of steroids
(R-RNO-8957322)
Mineralocorticoid biosynthesis
(R-RNO-193993)
3-beta-hydroxy-delta5-steroid dehydrogenase activity
(GO:0003854)
3-keto sterol reductase activity
(GO:0000253)
5alpha-androstane-3beta,17beta-diol dehydrogenase activity
(GO:0047024)
C21-steroid hormone metabolic process
(GO:0008207)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Hippocampus development
(GO:0021766)
Intracellular membrane-bounded organelle
(GO:0043231)
Mitochondrial membrane
(GO:0031966)
Oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
(GO:0016616)
Progesterone metabolic process
(GO:0042448)
Regulation of steroid biosynthetic process
(GO:0050810)
Response to corticosterone
(GO:0051412)
Steroid binding
(GO:0005496)
Steroid biosynthetic process
(GO:0006694)
Steroid dehydrogenase activity
(GO:0016229)

Other Information

Proteins

3 beta-hydroxysteroid dehydrogenase type 3

Genular Protein ID: 1302158280

Symbol: 3BHS5_RAT

Name: 3 beta-hydroxysteroid dehydrogenase type 3

UniProtKB Accession Codes:

P27364 Q569C6

Database IDs:

Citations:

PubMed ID: 2249649

Title: Structure and sexual dimorphic expression of a liver-specific rat 3 beta-hydroxysteroid dehydrogenase/isomerase.

PubMed ID: 2249649

DOI: 10.1210/endo-127-6-3237

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1537836

Title: Expression of liver-specific member of the 3 beta-hydroxysteroid dehydrogenase family, an isoform possessing an almost exclusive 3-ketosteroid reductase activity.

PubMed ID: 1537836

DOI: 10.1016/s0021-9258(18)42863-3

Sequence Information:

Length: 373
Mass: 42206
Checksum: B96538F2EF056935
Sequence:

MPGWSCLVTG AGGFLGQRIV QMLVQEKELQ EVRVLYRTFS PKHKEELSKL QTKAKVTVLR 
GDIVDAQFLR RACQGMSVII HTAAALDIAG FLPRQTILDV NVKGTQLLLD ACVEASVPAF 
IYSSSTGVAG PNSYKETILN DREEEHREST WSNPYPYSKR MAEKAVLAAN GSILKNGGTF 
HTCALRLPFI YGEESQIIST MVNRALKNNS IIKRHATFSI ANPVYVGNAA WAHILAARGL 
RDPEKSQSIQ GQFYYISDDT PHQSYDDLNY TLSKEWGFCL DSSWSLPLPL LYWLAFLLET 
VSFLLRPFYN YRPPFNRFMV TILNSVFTIS YKKAQRDLGY EPLVSWEEAK QKTSEWIGTL 
VEQHRETLDT KSQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.