Details for: Iapp

Gene ID: 24476

Symbol: Iapp

Ensembl ID: ENSRNOG00000012417

Description: islet amyloid polypeptide

Associated with

Other Information

Genular Protein ID: 2276343766

Symbol: IAPP_RAT

Name: Islet amyloid polypeptide

UniProtKB Accession Codes:

P12969

Database IDs:

AGR 1 AlphaFoldDB 1 BMRB 1 Bgee 1 BioGRID 1 CTD 1 EMBL 4 EMDB 5 Ensembl 4 EvolutionaryTrace 1 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 6 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 eggNOG 1

Citations:

PubMed ID: 2668946

Title: Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

PubMed ID: 2668946

DOI: 10.1073/pnas.86.15.5738

PubMed ID: 2654937

Title: Rat amylin: cloning and tissue-specific expression in pancreatic islets.

PubMed ID: 2654937

DOI: 10.1073/pnas.86.9.3127

PubMed ID: 2223885

Title: Islet amyloid polypeptide: structure and upstream sequences of the IAPP gene in rat and man.

PubMed ID: 2223885

DOI: 10.1016/0167-4781(90)90210-s

PubMed ID: 2679555

Title: Isolation and sequence determination of rat islet amyloid polypeptide.

PubMed ID: 2679555

DOI: 10.1016/0006-291x(89)91733-6

PubMed ID: 2357234

Title: Regional distribution and molecular forms of rat islet amyloid polypeptide.

PubMed ID: 2357234

DOI: 10.1016/0006-291x(90)90400-h

PubMed ID: 2666169

Title: Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species.

PubMed ID: 2666169

DOI: 10.1016/0014-5793(89)81467-x

PubMed ID: 19360098

Title: Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding.

PubMed ID: 19360098

DOI: 10.1371/journal.pcbi.1000357

PubMed ID: 19456151

Title: Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.

PubMed ID: 19456151

DOI: 10.1021/ja9010095

Sequence Information:

  • Length: 93
  • Mass: 10015
  • Checksum: 5A76C92E624DA962
  • Sequence:
    • MRCISRLPAV LLILSVALGH LRATPVGSGT NPQVDKRKCN TATCATQRLA NFLVRSSNNL 
GPVLPPTNVG SNTYGKRNVA EDPNRESLDF LLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.