Genular: Defining Cellular Identity and Function

Details for: Idh1

Gene ID: 24479

Symbol: Idh1

Ensembl ID: ENSRNOG00000015020

Description: isocitrate dehydrogenase (NADP(+)) 1

Associated with

Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Metabolism
(R-RNO-1430728)
Metabolism of cofactors
(R-RNO-8978934)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Nadph regeneration
(R-RNO-389542)
Neutrophil degranulation
(R-RNO-6798695)
Peroxisomal protein import
(R-RNO-9033241)
Protein localization
(R-RNO-9609507)
2-oxoglutarate metabolic process
(GO:0006103)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Female gonad development
(GO:0008585)
Glutathione metabolic process
(GO:0006749)
Glyoxylate cycle
(GO:0006097)
Identical protein binding
(GO:0042802)
Isocitrate dehydrogenase (nadp+) activity
(GO:0004450)
Isocitrate metabolic process
(GO:0006102)
Magnesium ion binding
(GO:0000287)
Mitochondrion
(GO:0005739)
Nad binding
(GO:0051287)
Nadp binding
(GO:0050661)
Nadp metabolic process
(GO:0006739)
Peroxisome
(GO:0005777)
Protein homodimerization activity
(GO:0042803)
Regulation of phospholipid biosynthetic process
(GO:0071071)
Regulation of phospholipid catabolic process
(GO:0060696)
Response to organic cyclic compound
(GO:0014070)
Response to oxidative stress
(GO:0006979)
Response to steroid hormone
(GO:0048545)
Tricarboxylic acid cycle
(GO:0006099)

Other Information

Proteins

Isocitrate dehydrogenase [NADP] cytoplasmic

Genular Protein ID: 1540172257

Symbol: IDHC_RAT

Name: Isocitrate dehydrogenase [NADP] cytoplasmic

UniProtKB Accession Codes:

P41562 P80300

Database IDs:

Citations:

PubMed ID: 8083215

Title: Cytosolic NADP(+)-dependent isocitrate dehydrogenase. Isolation of rat cDNA and study of tissue-specific and developmental expression of mRNA.

PubMed ID: 8083215

DOI: 10.1016/s0021-9258(17)31629-0

PubMed ID: 7787968

Title: Structural characterization of cytosolic NADP(+)-dependent isocitrate dehydrogenase from rat ovary.

PubMed ID: 7787968

DOI: 10.1159/000474966

PubMed ID: 10521434

Title: The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase.

PubMed ID: 10521434

DOI: 10.1074/jbc.274.43.30527

Sequence Information:

Length: 414
Mass: 46734
Checksum: CF69EE8746DC1AF6
Sequence:

MSRKIHGGSV VEMQGDEMTR IIWELIKEKL ILPYVELDLH SYDLGIENRD ATNDQVTKDA 
AEAIKKYNVG VKCATITPDE KRVEEFKLKQ MWKSPNGTIR NILGGTVFRE AIICKNIPRL 
VTGWVKPIII GRHAYGDQYR ATDFVVPGPG KVEITYTPKD GSQKVTYLVH DFEEGGGVAM 
GMYNQDKSIE DFAHSSFQMA LSKGWPLYLS TKNTILKKYD GRFKDIFQEI YDKQYKSKFE 
AQKIWYEHRL IDDMVAQAMK SEGGFIWACK NYDGDVQSDS VAQGYGSLGM MTSVLICPDG 
KTVEAEAAHG TVTRHYRMYQ KGQETSTNPI ASIFAWSRGL AHRAKLDNNT ELSFFANALE 
EVCIETIEAG FMTKDLAACI KGLPNVQRSD YLNTFEFMDK LGENLKAKLA QAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.