Genular: Defining Cellular Identity and Function

Details for: Igfbp3

Gene ID: 24484

Symbol: Igfbp3

Ensembl ID: ENSRNOG00000061910

Description: insulin-like growth factor binding protein 3

Associated with

Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Rna polymerase ii transcription
(R-RNO-73857)
Tp53 regulates transcription of cell death genes
(R-RNO-5633008)
Tp53 regulates transcription of death receptors and ligands
(R-RNO-6803211)
Transcriptional regulation by tp53
(R-RNO-3700989)
Apoptotic process
(GO:0006915)
Cellular response to estradiol stimulus
(GO:0071392)
Cellular response to thyroglobulin triiodothyronine
(GO:1904017)
Extracellular space
(GO:0005615)
Female pregnancy
(GO:0007565)
Fibronectin binding
(GO:0001968)
Heterochromatin
(GO:0000792)
Insulin-like growth factor binary complex
(GO:0042568)
Insulin-like growth factor binding
(GO:0005520)
Insulin-like growth factor i binding
(GO:0031994)
Insulin-like growth factor ii binding
(GO:0031995)
Insulin-like growth factor ternary complex
(GO:0042567)
Mapk cascade
(GO:0000165)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of smooth muscle cell migration
(GO:0014912)
Negative regulation of smooth muscle cell proliferation
(GO:0048662)
Negative regulation of testosterone secretion
(GO:2000844)
Nucleus
(GO:0005634)
Osteoblast differentiation
(GO:0001649)
Platelet alpha granule
(GO:0031091)
Positive regulation of apoptotic dna fragmentation
(GO:1902512)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cardiac muscle cell apoptotic process
(GO:0010666)
Positive regulation of insulin-like growth factor receptor signaling pathway
(GO:0043568)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of myoblast differentiation
(GO:0045663)
Protein binding
(GO:0005515)
Protein tyrosine phosphatase activator activity
(GO:0008160)
Regulation of cell growth
(GO:0001558)
Regulation of glucose metabolic process
(GO:0010906)
Regulation of growth
(GO:0040008)
Regulation of insulin-like growth factor receptor signaling pathway
(GO:0043567)
Response to caloric restriction
(GO:0061771)
Response to growth hormone
(GO:0060416)
Response to hypoxia
(GO:0001666)
Response to insulin
(GO:0032868)
Response to insulin-like growth factor stimulus
(GO:1990418)
Response to lipopolysaccharide
(GO:0032496)
Response to organic cyclic compound
(GO:0014070)
Response to xenobiotic stimulus
(GO:0009410)
Type b pancreatic cell proliferation
(GO:0044342)

Other Information

Proteins

Genular Protein ID: 3573170056

Symbol: IBP3_RAT

Name: Insulin-like growth factor-binding protein 3

UniProtKB Accession Codes:

P15473

Database IDs:

Citations:

PubMed ID: 2480787

Title: Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA.

PubMed ID: 2480787

DOI: 10.1016/s0006-291x(89)80052-x

PubMed ID: 1689154

Title: Cloning and characterization of the growth hormone-dependent insulin-like growth factor binding protein (IGFBP-3) in the rat.

PubMed ID: 1689154

DOI: 10.1016/0006-291x(90)90894-s

PubMed ID: 3190697

Title: Isolation and NH2-terminal amino acid sequences of rat serum carrier proteins for insulin-like growth factors.

PubMed ID: 3190697

DOI: 10.1016/s0006-291x(88)80758-7

PubMed ID: 2443135

Title: Binding proteins for insulin-like growth factors in adult rat serum. Comparison with other human and rat binding proteins.

PubMed ID: 2443135

DOI: 10.1016/s0006-291x(87)80136-5

PubMed ID: 2480123

Title: Identification of a novel binding protein for insulin-like growth factors in adult rat serum.

PubMed ID: 2480123

DOI: 10.1016/0006-291x(89)91053-x

Sequence Information:

Length: 292
Mass: 31680
Checksum: 1887D5E2A528F3B2
Sequence:

MHPARPALWA AALTALTLLR GPPVARAGAG AVGAGPVVRC EPCDARALAQ CAPPPTAPAC 
TELVREPGCG CCLTCALREG DACGVYTERC GTGLRCQPRP AEQYPLKALL NGRGFCANAS 
AASNLSAYLP SQPSPGNTTE SEEDHNAGSV ESQVVPSTHR VTDSKFHPLH SKMEVIIKGQ 
ARDSQRYKVD YESQSTDTQN FSSESKRETE YGPCRREMED TLNHLKFLNV LSPRGVHIPN 
CDKKGFYKKK QCRPSKGRKR GFCWCVDKYG QPLPGYDTKG KDDVHCLSVQ SQ

Genular Protein ID: 4165551247

Symbol: A0A0G2K4Q9_RAT

Name: N/A

UniProtKB Accession Codes:

A0A0G2K4Q9

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

Length: 292
Mass: 31653
Checksum: 2CF20DA8BD91E838
Sequence:

MHPARPALWA AALTALTLLR GPPVARAGAG AVGAGPVVRC EPCDARALAQ CAPPPTAPAC 
TELVREPGCG CCLTCALREG DACGVYTERC GTGLRCQPRP AEQYPLKALL NGRGFCANAS 
AASSLSAYLP SQPSPGNTTE SEEDHNAGSV ESQVVPSTHR VTDSKFHPLH SKMEVIIKGQ 
ARDSQRYKVD YESQSTDTQN FSSESKRETE YGPCRREMED TLNHLKFLNV LSPRGVHIPN 
CDKKGFYKKK QCRPSKGRKR GFCWCVDKYG QPLPGYDTKG KDDVHCLSVQ SQ

Genular Protein ID: 3877625694

Symbol: A1A5Q9_RAT

Name: N/A

UniProtKB Accession Codes:

A1A5Q9

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 153
Mass: 15577
Checksum: 6053284D220794B7
Sequence:

MHPARPALWA AALTALTLLR GPPVARAGAG AVGAGPVVRC EPCDARALAQ CAPPPTAPAC 
TELVREPGCG CCLTCALREG DACGVYTERC GTGLRCQPRP AEQYPLKALL NGRGFCANAS 
AASSLSAYLP SQPSPGKLSL SRAPRALPGT RRG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Igfbp3

Associated with

Other Information

Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA. PubMed ID: 2480787

Cloning and characterization of the growth hormone-dependent insulin-like growth factor binding protein (IGFBP-3) in the rat. PubMed ID: 1689154

Isolation and NH2-terminal amino acid sequences of rat serum carrier proteins for insulin-like growth factors. PubMed ID: 3190697

Binding proteins for insulin-like growth factors in adult rat serum. Comparison with other human and rat binding proteins. PubMed ID: 2443135

Identification of a novel binding protein for insulin-like growth factors in adult rat serum. PubMed ID: 2480123

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 2480787

PubMed ID: 1689154

PubMed ID: 3190697

PubMed ID: 2443135

PubMed ID: 2480123

PubMed ID: 15057822

PubMed ID: 15489334