Genular: Defining Cellular Identity and Function

Details for: Il1b

Gene ID: 24494

Symbol: Il1b

Ensembl ID: ENSRNOG00000004649

Description: interleukin 1 beta

Associated with

C-type lectin receptors (clrs)
(R-RNO-5621481)
Clec7a (dectin-1) signaling
(R-RNO-5607764)
Clec7a/inflammasome pathway
(R-RNO-5660668)
Cytokine signaling in immune system
(R-RNO-1280215)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Interleukin-1 family signaling
(R-RNO-446652)
Interleukin-1 processing
(R-RNO-448706)
Interleukin-1 signaling
(R-RNO-9020702)
Programmed cell death
(R-RNO-5357801)
Pyroptosis
(R-RNO-5620971)
Regulated necrosis
(R-RNO-5218859)
Signaling by interleukins
(R-RNO-449147)
Chronic inflammatory response to antigenic stimulus
(GO:0002439)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Ectopic germ cell programmed cell death
(GO:0035234)
Fever generation
(GO:0001660)
Hyaluronan biosynthetic process
(GO:0030213)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Integrin binding
(GO:0005178)
Interleukin-1 receptor binding
(GO:0005149)
Jnk cascade
(GO:0007254)
Learning or memory
(GO:0007611)
Memory
(GO:0007613)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of glucose transmembrane transport
(GO:0010829)
Negative regulation of glutamate secretion
(GO:0014050)
Negative regulation of lipid metabolic process
(GO:0045833)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neutrophil chemotaxis
(GO:0030593)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of complement activation
(GO:0045917)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of fever generation
(GO:0031622)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glial cell differentiation
(GO:0045687)
Positive regulation of granulocyte macrophage colony-stimulating factor production
(GO:0032725)
Positive regulation of heterotypic cell-cell adhesion
(GO:0034116)
Positive regulation of immature t cell proliferation in thymus
(GO:0033092)
Positive regulation of interleukin-2 production
(GO:0032743)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of prostaglandin biosynthetic process
(GO:0031394)
Positive regulation of prostaglandin secretion
(GO:0032308)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of stress-activated mapk cascade
(GO:0032874)
Positive regulation of t cell proliferation
(GO:0042102)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of type ii interferon production
(GO:0032729)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Protein domain specific binding
(GO:0019904)
Receptor ligand activity
(GO:0048018)
Regulation of canonical nf-kappab signal transduction
(GO:0043122)
Response to atp
(GO:0033198)
Response to carbohydrate
(GO:0009743)
Response to estradiol
(GO:0032355)
Response to ethanol
(GO:0045471)
Response to gamma radiation
(GO:0010332)
Response to hypoxia
(GO:0001666)
Response to immobilization stress
(GO:0035902)
Response to isolation stress
(GO:0035900)
Response to l-ascorbic acid
(GO:0033591)
Response to lipopolysaccharide
(GO:0032496)
Response to nutrient
(GO:0007584)
Response to organic cyclic compound
(GO:0014070)
Response to organonitrogen compound
(GO:0010243)
Response to ozone
(GO:0010193)
Response to peptide hormone
(GO:0043434)
Response to stilbenoid
(GO:0035634)
Response to vitamin d
(GO:0033280)
Response to xenobiotic stimulus
(GO:0009410)
Sequestering of triglyceride
(GO:0030730)
Signal transduction
(GO:0007165)
Social behavior
(GO:0035176)
Vascular endothelial growth factor production
(GO:0010573)

Other Information

Proteins

Q5BKB0_RAT

Genular Protein ID: 1603283660

Symbol: Q5BKB0_RAT

Name: N/A

UniProtKB Accession Codes:

Q5BKB0

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

Length: 268
Mass: 30659
Checksum: 179B699CF1EB2428
Sequence:

MATVPELNCE IAAFDSEEND LFFEADRPQK IKDCFQALDL GCPDESIQLQ ISQQHLDKSF 
RKAVSLIVAV EKLWQLPMSC PWSFQDEDPS TFFSFIFEEE PVLCDSWDDD DLLVCDVPIR 
QLHCRLRDEQ QKCLVLSDPC ELKALHLNGQ NISQQVVFSM SFVQGETSND KIPVALGLKG 
KNLYLSCVMK DGTPTLQLES VDPKQYPKKK MEKRFVFNKI EVKTKVEFES AQFPNWYIST 
SQAEHRPVFL GNSNGRDIVD FTMEPVSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Il1b

Associated with

Other Information

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

Database document:

PubMed ID: 15057822