Genular: Defining Cellular Identity and Function

Details for: Ins1

Gene ID: 24505

Symbol: Ins1

Ensembl ID: ENSRNOG00000012052

Description: insulin 1

Associated with

Asparagine n-linked glycosylation
(R-RNO-446203)
Copi-mediated anterograde transport
(R-RNO-6807878)
Er to golgi anterograde transport
(R-RNO-199977)
Insulin processing
(R-RNO-264876)
Insulin receptor recycling
(R-RNO-77387)
Insulin receptor signalling cascade
(R-RNO-74751)
Intracellular signaling by second messengers
(R-RNO-9006925)
Irs activation
(R-RNO-74713)
Membrane trafficking
(R-RNO-199991)
Metabolism of proteins
(R-RNO-392499)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Peptide hormone metabolism
(R-RNO-2980736)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Post-translational protein modification
(R-RNO-597592)
Signal attenuation
(R-RNO-74749)
Signaling by insulin receptor
(R-RNO-74752)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signal transduction
(R-RNO-162582)
Synthesis, secretion, and deacylation of ghrelin
(R-RNO-422085)
Transport to the golgi and subsequent modification
(R-RNO-948021)
Vesicle-mediated transport
(R-RNO-5653656)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to oxygen-containing compound
(GO:1901701)
Cytosol
(GO:0005829)
Extracellular space
(GO:0005615)
Glucose homeostasis
(GO:0042593)
Glucose metabolic process
(GO:0006006)
Hormone activity
(GO:0005179)
Insulin receptor binding
(GO:0005158)
Insulin receptor signaling pathway
(GO:0008286)
Positive regulation of protein secretion
(GO:0050714)
Receptor internalization
(GO:0031623)
Response to camp
(GO:0051591)
Response to cytokine
(GO:0034097)
Response to organic substance
(GO:0010033)
Response to peptide hormone
(GO:0043434)

Other Information

Proteins

Insulin-1

Genular Protein ID: 3224705653

Symbol: INS1_RAT

Name: Insulin-1

UniProtKB Accession Codes:

P01322

Database IDs:

Citations:

PubMed ID: 498283

Title: Isolation and characterization of a cloned rat insulin gene.

PubMed ID: 498283

DOI: 10.1016/0092-8674(79)90070-9

PubMed ID: 498284

Title: The structure and evolution of the two nonallelic rat preproinsulin genes.

PubMed ID: 498284

DOI: 10.1016/0092-8674(79)90071-0

PubMed ID: 6249167

Title: The structure of rat preproinsulin genes.

PubMed ID: 6249167

DOI: 10.1111/j.1749-6632.1980.tb47271.x

PubMed ID: 4311938

Title: Proinsulin and the biosynthesis of insulin.

PubMed ID: 4311938

DOI: 10.1016/b978-0-12-571125-8.50008-9

PubMed ID: 4640931

Title: Primary structures of the proinsulin connecting peptides of the rat and the horse.

PubMed ID: 4640931

DOI: 10.1016/s0021-9258(20)81791-8

PubMed ID: 4554104

Title: Rat-proinsulin C-peptides. Amino-acid sequences.

PubMed ID: 4554104

DOI: 10.1111/j.1432-1033.1972.tb01680.x

Sequence Information:

Length: 110
Mass: 12421
Checksum: 51D606DA54AE3533
Sequence:

MALWMRFLPL LALLVLWEPK PAQAFVKQHL CGPHLVEALY LVCGERGFFY TPKSRREVED 
PQVPQLELGG GPEAGDLQTL ALEVARQKRG IVDQCCTSIC SLYQLENYCN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ins1

Associated with

Other Information

Isolation and characterization of a cloned rat insulin gene. PubMed ID: 498283

The structure and evolution of the two nonallelic rat preproinsulin genes. PubMed ID: 498284

The structure of rat preproinsulin genes. PubMed ID: 6249167

Proinsulin and the biosynthesis of insulin. PubMed ID: 4311938

Primary structures of the proinsulin connecting peptides of the rat and the horse. PubMed ID: 4640931