Details for: Irf1

Gene ID: 24508

Symbol: Irf1

Description: interferon regulatory factor 1

Associated with

  • Apoptotic process
    (GO:0006915)
  • Canonical nf-kappab signal transduction
    (GO:0007249)
  • Cd8-positive, alpha-beta t cell differentiation
    (GO:0043374)
  • Cellular response to exogenous dsrna
    (GO:0071360)
  • Cellular response to interferon-beta
    (GO:0035458)
  • Cellular response to interleukin-1
    (GO:0071347)
  • Cellular response to mechanical stimulus
    (GO:0071260)
  • Cellular response to peptide hormone stimulus
    (GO:0071375)
  • Cellular response to retinoic acid
    (GO:0071300)
  • Cellular response to tumor necrosis factor
    (GO:0071356)
  • Cellular response to type ii interferon
    (GO:0071346)
  • Chromatin
    (GO:0000785)
  • Cytoplasm
    (GO:0005737)
  • Defense response to virus
    (GO:0051607)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Female pregnancy
    (GO:0007565)
  • Immune system process
    (GO:0002376)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of regulatory t cell differentiation
    (GO:0045590)
  • Negative regulation of tyrosine phosphorylation of stat protein
    (GO:0042532)
  • Nucleus
    (GO:0005634)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of interferon-beta production
    (GO:0032728)
  • Positive regulation of interleukin-12 production
    (GO:0032735)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of type i interferon production
    (GO:0032481)
  • Protein binding
    (GO:0005515)
  • Regulation of cd8-positive, alpha-beta t cell proliferation
    (GO:2000564)
  • Regulation of cell cycle
    (GO:0051726)
  • Regulation of cell population proliferation
    (GO:0042127)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of gene expression
    (GO:0010468)
  • Regulation of myd88-dependent toll-like receptor signaling pathway
    (GO:0034124)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to growth hormone
    (GO:0060416)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Type ii interferon-mediated signaling pathway
    (GO:0060333)

Other Information

Genular Protein ID: 1153800084

Symbol: IRF1_RAT

Name: Interferon regulatory factor 1

UniProtKB Accession Codes:

P23570

Database IDs:

AGR 1 AlphaFoldDB 1 CDD 1 CTD 1 ChEMBL 1 EMBL 1 GO 43 Gene3D 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 eggNOG 1

Citations:

PubMed ID: 2342469

Title: Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells.

PubMed ID: 2342469

DOI: 10.1128/mcb.10.6.3087-3094.1990

Sequence Information:

  • Length: 328
  • Mass: 37065
  • Checksum: B94ADE14E975BBD9
  • Sequence:
    • MPITRMRMRP WLEMQINSNQ IPGLSWINKE EMIFQIPWKH AALHGWDINK DACLFRSWAI 
HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPPLTKNQR 
KERKSKSSRD TKSKTKRKLC GDSSPDTLSD GLSSSTLPDD HSSYTAQGYL GQDLDMDRDI 
TPALSPCVVS SSLSEWHMQM DIMPDSTTDL YNLQVSPMPS TSEAATDEDE EGKLPEDIMK 
LFEQSEWQPT HVDGKGYLLN EPGAQLSTVY GDFSCKEEPE IDSPGGDIEI GIQRVFTEMK 
NMDPVMWMDT LLGNSTRPPS IQAIPCAP

Genular Protein ID: 3990228899

Symbol: Q6DGG4_RAT

Name: N/A

UniProtKB Accession Codes:

Q6DGG4

Database IDs:

ARBA 7 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 EMBL 6 GO 4 Gene3D 1 HOGENOM 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PROSITE 3 Pfam 1 Proteomes 1 RGD 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 TreeFam 1 VEuPathDB 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

  • Length: 328
  • Mass: 37080
  • Checksum: EC18398A92747D75
  • Sequence:
    • MPITRMRMRP WLEMQINSNQ IPGLSWINKE EMIFQIPWKH AAKHGWDINK DACLFRSWAI 
HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPPLTKNQR 
KERKSKSSRD TKSKTKRKLC GDSSPDTLSD GLSSSTLPDD HSSYTAQGYL GQDLDMDRDI 
TPALSPCVVS SSLSEWHMQM DIMPDSTTDL YNLQVSPMPS TSEAATDEDE EGKLPEDIMK 
LFEQSEWQPT HVDGKGYLLN EPGAQLSTVY GDFSCKEEPE IDSPGGDIEI GIQRVFTEMK 
NMDPVMWMDT LLGNSTRPPS IQAIPCAP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.