Details for: Kcna1
Associated with
Other Information
Genular Protein ID: 4030154423
Symbol: KCNA1_RAT
Name: Voltage-gated potassium channel subunit Kv1.1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3191911
Title: Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems.
PubMed ID: 3191911
PubMed ID: 2539643
Title: Expression of a cloned rat brain potassium channel in Xenopus oocytes.
PubMed ID: 2539643
PubMed ID: 2348860
Title: Heteromultimeric channels formed by rat brain potassium-channel proteins.
PubMed ID: 2348860
DOI: 10.1038/345535a0
PubMed ID: 8038169
Title: Phosphorylation by protein kinase A of RCK1 K+ channels expressed in Xenopus oocytes.
PubMed ID: 8038169
DOI: 10.1021/bi00195a021
PubMed ID: 12907802
Title: Nervous system targets of RNA editing identified by comparative genomics.
PubMed ID: 12907802
PubMed ID: 9334400
Title: Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes.
PubMed ID: 9334400
PubMed ID: 10896669
Title: Subunit composition determines Kv1 potassium channel surface expression.
PubMed ID: 10896669
PubMed ID: 11086297
Title: Subunit composition and novel localization of K+ channels in spinal cord.
PubMed ID: 11086297
DOI: 10.1002/1096-9861(20000101)429:1<166::aid-cne13>3.0.co;2-y
PubMed ID: 12114518
Title: Modulation of a brain voltage-gated K+ channel by syntaxin 1A requires the physical interaction of Gbetagamma with the channel.
PubMed ID: 12114518
PubMed ID: 12177193
Title: Two heteromeric Kv1 potassium channels differentially regulate action potential firing.
PubMed ID: 12177193
PubMed ID: 12777451
Title: Presynaptic rat Kv1.2 channels suppress synaptic terminal hyperexcitability following action potential invasion.
PubMed ID: 12777451
PubMed ID: 12681381
Title: Analysis of phosphorylation-dependent modulation of Kv1.1 potassium channels.
PubMed ID: 12681381
PubMed ID: 7477295
Title: Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.
PubMed ID: 7477295
DOI: 10.1038/378085a0
PubMed ID: 16306173
Title: Mu opioid receptor activation inhibits GABAergic inputs to basolateral amygdala neurons through Kv1.1/1.2 channels.
PubMed ID: 16306173
PubMed ID: 16504945
Title: The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1.
PubMed ID: 16504945
PubMed ID: 17855588
Title: Manipulation of the potassium channel Kv1.1 and its effect on neuronal excitability in rat sensory neurons.
PubMed ID: 17855588
PubMed ID: 17917103
Title: Ionic channel function in action potential generation: current perspective.
PubMed ID: 17917103
PubMed ID: 17869444
Title: Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus.
PubMed ID: 17869444
PubMed ID: 20805574
Title: Arrangement of Kv1 alpha subunits dictates sensitivity to tetraethylammonium.
PubMed ID: 20805574
PubMed ID: 21483673
Title: Evidence for presence and functional effects of Kv1.1 channels in beta-cells: general survey and results from mceph/mceph mice.
PubMed ID: 21483673
PubMed ID: 22206926
Title: Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
PubMed ID: 22206926
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 23725331
Title: Pharmacological characteristics of Kv1.1- and Kv1.2-containing channels are influenced by the stoichiometry and positioning of their alpha subunits.
PubMed ID: 23725331
DOI: 10.1042/bj20130297
PubMed ID: 23318870
Title: A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets.
PubMed ID: 23318870
PubMed ID: 25514171
Title: Mesomartoxin, a new K(v)1.2-selective scorpion toxin interacting with the channel selectivity filter.
PubMed ID: 25514171
PubMed ID: 10884227
Title: Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels.
PubMed ID: 10884227
Sequence Information:
- Length: 495
- Mass: 56379
- Checksum: 29804463133F5D31
- Sequence:
MTVMSGENAD EASAAPGHPQ DGSYPRQADH DDHECCERVV INISGLRFET QLKTLAQFPN TLLGNPKKRM RYFDPLRNEY FFDRNRPSFD AILYYYQSGG RLRRPVNVPL DMFSEEIKFY ELGEEAMEKF REDEGFIKEE ERPLPEKEYQ RQVWLLFEYP ESSGPARVIA IVSVMVILIS IVIFCLETLP ELKDDKDFTG TIHRIDNTTV IYTSNIFTDP FFIVETLCII WFSFELVVRF FACPSKTDFF KNIMNFIDIV AIIPYFITLG TEIAEQEGNQ KGEQATSLAI LRVIRLVRVF RIFKLSRHSK GLQILGQTLK ASMRELGLLI FFLFIGVILF SSAVYFAEAE EAESHFSSIP DAFWWAVVSM TTVGYGDMYP VTIGGKIVGS LCAIAGVLTI ALPVPVIVSN FNYFYHRETE GEEQAQLLHV SSPNLASDSD LSRRSSSTIS KSEYMEIEED MNNSIAHYRQ ANIRTGNCTA TDQNCVNKSK LLTDV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.