Genular: Defining Cellular Identity and Function

Details for: Lpl

Gene ID: 24539

Symbol: Lpl

Ensembl ID: ENSRNOG00000012181

Description: lipoprotein lipase

Associated with

Assembly of active lpl and lipc lipase complexes
(R-RNO-8963889)
Metabolism
(R-RNO-1430728)
Metabolism of fat-soluble vitamins
(R-RNO-6806667)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein remodeling
(R-RNO-8963899)
Retinoid metabolism and transport
(R-RNO-975634)
Sensory perception
(R-RNO-9709957)
Transport of small molecules
(R-RNO-382551)
Visual phototransduction
(R-RNO-2187338)
1-acyl-2-lysophosphatidylserine acylhydrolase activity
(GO:0052740)
Apolipoprotein binding
(GO:0034185)
Calcium ion binding
(GO:0005509)
Catalytic complex
(GO:1902494)
Cell surface
(GO:0009986)
Cellular response to fatty acid
(GO:0071398)
Cellular response to nutrient
(GO:0031670)
Cholesterol homeostasis
(GO:0042632)
Chylomicron
(GO:0042627)
Chylomicron remodeling
(GO:0034371)
Extracellular space
(GO:0005615)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Heparan sulfate proteoglycan binding
(GO:0043395)
Heparin binding
(GO:0008201)
High-density lipoprotein particle remodeling
(GO:0034375)
Lipid catabolic process
(GO:0016042)
Lipoprotein lipase activity
(GO:0004465)
Lipoprotein particle binding
(GO:0071813)
Low-density lipoprotein particle mediated signaling
(GO:0055096)
Negative regulation of cellular response to insulin stimulus
(GO:1900077)
Phosphatidylserine 1-acylhydrolase activity
(GO:0052739)
Phospholipase a1 activity
(GO:0008970)
Plasma membrane
(GO:0005886)
Positive regulation of adipose tissue development
(GO:1904179)
Positive regulation of chemokine (c-x-c motif) ligand 2 production
(GO:2000343)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of cholesterol storage
(GO:0010886)
Positive regulation of fat cell differentiation
(GO:0045600)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of interleukin-1 beta production
(GO:0032731)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of macrophage derived foam cell differentiation
(GO:0010744)
Positive regulation of sequestering of triglyceride
(GO:0010890)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Protein homodimerization activity
(GO:0042803)
Response to bacterium
(GO:0009617)
Response to xenobiotic stimulus
(GO:0009410)
Signaling receptor binding
(GO:0005102)
Triglyceride binding
(GO:0017129)
Triglyceride biosynthetic process
(GO:0019432)
Triglyceride catabolic process
(GO:0019433)
Triglyceride homeostasis
(GO:0070328)
Triglyceride lipase activity
(GO:0004806)
Very-low-density lipoprotein particle
(GO:0034361)
Very-low-density lipoprotein particle remodeling
(GO:0034372)

Other Information

Proteins

Lipoprotein lipase

Genular Protein ID: 2647347642

Symbol: LIPL_RAT

Name: Lipoprotein lipase

UniProtKB Accession Codes:

Q06000

Database IDs:

Citations:

PubMed ID: 1339374

Title: Sequence of rat lipoprotein lipase-encoding cDNA.

PubMed ID: 1339374

DOI: 10.1016/0378-1119(92)90127-b

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2233752

Title: Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms.

PubMed ID: 2233752

DOI: 10.1210/mend-4-9-1416

PubMed ID: 19715756

Title: Lipoprotein lipase is nitrated in vivo after lipopolysaccharide challenge.

PubMed ID: 19715756

DOI: 10.1016/j.freeradbiomed.2009.08.020

PubMed ID: 19527804

Title: Discovery of lipoprotein lipase pI isoforms and contributions to their characterization.

PubMed ID: 19527804

DOI: 10.1016/j.jprot.2009.06.002

Sequence Information:

Length: 474
Mass: 53082
Checksum: F4F6F4BCCA4F1626
Sequence:

MESKALLLVA LGVWLQSLTA FRGGVAAADG GRDFSDIESK FALRTPEDTA EDTCHLIPGL 
ADSVSNCHFN HSSKTFVVIH GWTVTGMYES WVPKLVAALY KREPDSNVIV VDWLYRAQQH 
YPVSAGYTKL VGNDVARFIN WLEEEFNYPL DNVHLLGYSL GAHAAGVAGS LTNKKVNRIT 
GLDPAGPNFE YAEAPSRLSP DDADFVDVLH TFTRGSPGRS IGIQKPVGHV DIYPNGGTFQ 
PGCNIGEAIR VIAEKGLGDV DQLVKCSHER SIHLFIDSLL NEENPSKAYR CNSKEAFEKG 
LCLSCRKNRC NNVGYEINKV RAKRSSKMYL KTRSQMPYKV FHYQVKIHFS GTENDKQNNQ 
AFEISLYGTV AESENIPFTL PEVATNKTYS FLIYTEVDIG ELLMMKLKWK NDSYFRWSDW 
WSSPSFVIEK IRVKAGETQK KVIFCAREKV SHLQKGKDAA VFVKCHDKSL KKSG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Lpl

Associated with

Other Information

Sequence of rat lipoprotein lipase-encoding cDNA. PubMed ID: 1339374

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms. PubMed ID: 2233752