Genular: Defining Cellular Identity and Function

Details for: Myc

Gene ID: 24577

Symbol: Myc

Ensembl ID: ENSRNOG00000004500

Description: MYC proto-oncogene, bHLH transcription factor

Associated with

Deubiquitination
(R-RNO-5688426)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Rna polymerase ii transcription
(R-RNO-73857)
Tfap2 (ap-2) family regulates transcription of cell cycle factors
(R-RNO-8866911)
Transcriptional regulation by the ap-2 (tfap2) family of transcription factors
(R-RNO-8864260)
Ub-specific processing proteases
(R-RNO-5689880)
Amino acid transport
(GO:0006865)
B cell apoptotic process
(GO:0001783)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
Cell population proliferation
(GO:0008283)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to interferon-alpha
(GO:0035457)
Cellular response to platelet-derived growth factor stimulus
(GO:0036120)
Cellular response to uv
(GO:0034644)
Chromatin remodeling
(GO:0006338)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Core promoter sequence-specific dna binding
(GO:0001046)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna-templated transcription
(GO:0006351)
Dna-templated transcription initiation
(GO:0006352)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna methylation-dependent heterochromatin formation
(GO:0006346)
Double-stranded dna binding
(GO:0003690)
E-box binding
(GO:0070888)
Eukaryotic initiation factor eif2 binding
(GO:0071074)
G0 to g1 transition
(GO:0045023)
G1/s transition of mitotic cell cycle
(GO:0000082)
Glucose metabolic process
(GO:0006006)
Hypothalamus development
(GO:0021854)
Identical protein binding
(GO:0042802)
Inner mitochondrial membrane organization
(GO:0007007)
Intracellular iron ion homeostasis
(GO:0006879)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
In utero embryonic development
(GO:0001701)
Mapk cascade
(GO:0000165)
Middle ear morphogenesis
(GO:0042474)
Mrna binding
(GO:0003729)
Myotube differentiation
(GO:0014902)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of stress-activated mapk cascade
(GO:0032873)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nk t cell proliferation
(GO:0001866)
Ovarian follicle development
(GO:0001541)
Pigmentation
(GO:0043473)
Positive regulation of b cell apoptotic process
(GO:0002904)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of mesenchymal cell proliferation
(GO:0002053)
Positive regulation of mitochondrial membrane potential
(GO:0010918)
Positive regulation of smooth muscle cell migration
(GO:0014911)
Protein-containing complex binding
(GO:0044877)
Protein-dna complex disassembly
(GO:0032986)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein processing
(GO:0016485)
Pyruvate transport
(GO:0006848)
Re-entry into mitotic cell cycle
(GO:0000320)
Regulation of apoptotic process
(GO:0042981)
Regulation of cell cycle process
(GO:0010564)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of oxidative phosphorylation
(GO:0002082)
Regulation of telomere maintenance
(GO:0032204)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to alkaloid
(GO:0043279)
Response to estradiol
(GO:0032355)
Response to gamma radiation
(GO:0010332)
Response to human chorionic gonadotropin
(GO:0044752)
Response to radiation
(GO:0009314)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Scf ubiquitin ligase complex binding
(GO:1905761)
Sequence-specific dna binding
(GO:0043565)
Skeletal muscle cell differentiation
(GO:0035914)
Transcription by rna polymerase ii
(GO:0006366)
Transcription coregulator binding
(GO:0001221)
Transcription regulator activator activity
(GO:0140537)
Ubiquitin protein ligase binding
(GO:0031625)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Myc proto-oncogene protein

Genular Protein ID: 1590301054

Symbol: MYC_RAT

Name: Myc proto-oncogene protein

UniProtKB Accession Codes:

P09416 A0A8L2Q2H7 Q6B500

Database IDs:

Citations:

PubMed ID: 3306601

Title: Characterization of rat c-myc and adjacent regions.

PubMed ID: 3306601

DOI: 10.1093/nar/15.16.6419

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3277717

Title: A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas.

PubMed ID: 3277717

DOI: 10.1016/0092-8674(88)90507-7

PubMed ID: 20352099

Title: Direct reprogramming of rat neural precursor cells and fibroblasts into pluripotent stem cells.

PubMed ID: 20352099

DOI: 10.1371/journal.pone.0009838

PubMed ID: 17304222

Title: Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation.

PubMed ID: 17304222

DOI: 10.1038/sj.emboj.7601569

Sequence Information:

Length: 453
Mass: 50561
Checksum: A64D6B02AF52E47F
Sequence:

MNFLWEVENP TVTTMPLNVS FANRNYDLDY DSVQPYFICD EEENFYHQQQ QSELQPPAPS 
EDIWKKFELL PTPPLSPSRR SGLCSPSYVA VATSFSPRED DDGGGGNFST ADQLEMMTEL 
LGGDMVNQSF ICDPDDETFI KNIIIQDCMW SGFSAAAKLV SEKLASYQAA RKDSTSLSPA 
RGHSVCSTSS LYLQDLTAAA SECIDPSVVF PYPLNDSSSP KSCTSSDSTA FSSSSDSLLS 
SESSPRATPE PLVLHEETPP TTSSDSEEEQ DDEEEIDVVS VEKRQPPAKR SESGSSPSRG 
HSKPPHSPLV LKRCHVSTHQ HNYAAPPSTR KDYPAAKRAK LDSGRVLKQI SNNRKCSSPR 
SSDTEENDKR RTHNVLERQR RNELKRSFFA LRDQIPELEN NEKAPKVVIL KKATAYILSV 
QADEHKLISE KDLLRKRREQ LKHKLEQLRN SGA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Myc

Associated with

Other Information

Characterization of rat c-myc and adjacent regions. PubMed ID: 3306601

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas. PubMed ID: 3277717

Direct reprogramming of rat neural precursor cells and fibroblasts into pluripotent stem cells. PubMed ID: 20352099