Details for: ALOX15

Gene ID: 246

Symbol: ALOX15

Ensembl ID: ENSG00000161905

Description: arachidonate 15-lipoxygenase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 9.3414
    Cell Significance Index: -3.8000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.9995
    Cell Significance Index: 183.9000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.4258
    Cell Significance Index: 52.5600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 2.0745
    Cell Significance Index: 50.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.9725
    Cell Significance Index: 63.1800
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.5844
    Cell Significance Index: 17.3300
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.4396
    Cell Significance Index: 14.8500
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.9188
    Cell Significance Index: 13.3400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.9025
    Cell Significance Index: 171.7500
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.6835
    Cell Significance Index: 7.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5544
    Cell Significance Index: 54.8500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5149
    Cell Significance Index: 10.9700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4733
    Cell Significance Index: 427.3700
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.3666
    Cell Significance Index: 3.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3464
    Cell Significance Index: 37.6800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3018
    Cell Significance Index: 49.0900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3015
    Cell Significance Index: 18.1000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1750
    Cell Significance Index: 12.1000
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.1067
    Cell Significance Index: 0.9800
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.0991
    Cell Significance Index: 0.9700
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.0907
    Cell Significance Index: 0.7800
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.0720
    Cell Significance Index: 0.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0418
    Cell Significance Index: 0.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0139
    Cell Significance Index: 9.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0109
    Cell Significance Index: 2.1900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0090
    Cell Significance Index: 0.3400
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.0046
    Cell Significance Index: 0.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0028
    Cell Significance Index: 0.0800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0019
    Cell Significance Index: 0.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0003
    Cell Significance Index: -0.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0009
    Cell Significance Index: -0.0300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0017
    Cell Significance Index: -0.6000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0021
    Cell Significance Index: -4.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0030
    Cell Significance Index: -5.4900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0032
    Cell Significance Index: -0.1400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0035
    Cell Significance Index: -5.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0041
    Cell Significance Index: -5.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0045
    Cell Significance Index: -0.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0045
    Cell Significance Index: -2.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0057
    Cell Significance Index: -4.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0058
    Cell Significance Index: -4.2700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0060
    Cell Significance Index: -0.1500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0067
    Cell Significance Index: -4.2600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0078
    Cell Significance Index: -4.3900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0084
    Cell Significance Index: -1.7700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0107
    Cell Significance Index: -3.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0114
    Cell Significance Index: -2.0500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0117
    Cell Significance Index: -1.5000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0124
    Cell Significance Index: -1.4500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0128
    Cell Significance Index: -0.5800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0128
    Cell Significance Index: -5.8300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0183
    Cell Significance Index: -0.3800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0203
    Cell Significance Index: -4.0300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0213
    Cell Significance Index: -3.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0253
    Cell Significance Index: -11.2000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0271
    Cell Significance Index: -3.9400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0295
    Cell Significance Index: -4.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0391
    Cell Significance Index: -4.4800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0392
    Cell Significance Index: -0.5900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0425
    Cell Significance Index: -5.4900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0440
    Cell Significance Index: -2.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0478
    Cell Significance Index: -4.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0500
    Cell Significance Index: -3.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0502
    Cell Significance Index: -3.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0527
    Cell Significance Index: -2.7400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0575
    Cell Significance Index: -2.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0606
    Cell Significance Index: -1.6500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0620
    Cell Significance Index: -4.7600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0626
    Cell Significance Index: -2.5700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0853
    Cell Significance Index: -5.2500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0908
    Cell Significance Index: -3.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0930
    Cell Significance Index: -5.2200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0942
    Cell Significance Index: -2.5200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0951
    Cell Significance Index: -1.6400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0961
    Cell Significance Index: -3.1500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0998
    Cell Significance Index: -3.1800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1054
    Cell Significance Index: -3.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1059
    Cell Significance Index: -5.5600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1060
    Cell Significance Index: -4.9800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1232
    Cell Significance Index: -4.2800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1255
    Cell Significance Index: -3.5800
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.1304
    Cell Significance Index: -1.7600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1314
    Cell Significance Index: -3.8600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1377
    Cell Significance Index: -3.6900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1381
    Cell Significance Index: -2.8100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1431
    Cell Significance Index: -3.5700
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1439
    Cell Significance Index: -2.0200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1495
    Cell Significance Index: -3.9300
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: -0.1519
    Cell Significance Index: -1.5300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1528
    Cell Significance Index: -4.0800
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1529
    Cell Significance Index: -1.8600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1586
    Cell Significance Index: -4.6700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1605
    Cell Significance Index: -11.3500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1608
    Cell Significance Index: -4.0100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1624
    Cell Significance Index: -2.3300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1697
    Cell Significance Index: -4.3400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1748
    Cell Significance Index: -5.5300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1757
    Cell Significance Index: -8.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1799
    Cell Significance Index: -5.0300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1830
    Cell Significance Index: -4.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzymatic Activity:** ALOX15 is a non-heme iron-dependent dioxygenase that catalyzes the hydroperoxidation of arachidonic acid, resulting in the production of 15-eicosatetraenoic acid (15-ETE) and other SPMs. 2. **Gene Expression:** The ALOX15 gene is widely expressed in various tissues, including the retina, blood vessels, trachea, and colon, suggesting its involvement in multiple physiological processes. 3. **Protein Structure:** The ALOX15 protein consists of 12 transmembrane domains, which facilitate its interaction with membrane lipids and other proteins. 4. **Regulatory Mechanisms:** ALOX15 expression is modulated by various signaling pathways, including interleukin-13 (IL-13) and interleukin-4 (IL-4) signaling, highlighting its role in immune system regulation. **Pathways and Functions:** 1. **Arachidonic Acid Metabolism:** ALOX15 is a key enzyme in the arachidonic acid metabolic pathway, which produces SPMs that regulate inflammation and tissue repair. 2. **Inflammatory Response:** ALOX15-derived SPMs, such as protectins and resolvins, modulate the inflammatory response by promoting the resolution of inflammation and tissue repair. 3. **Immune System Regulation:** ALOX15 expression is modulated by IL-13 and IL-4 signaling, suggesting its role in regulating immune system responses, including the positive regulation of adaptive immune responses. 4. **Wound Healing:** ALOX15-derived SPMs play a crucial role in wound healing by promoting the resolution of inflammation and tissue repair. **Clinical Significance:** 1. **Inflammatory Diseases:** ALOX15-derived SPMs have been implicated in the pathogenesis of inflammatory diseases, such as atherosclerosis, asthma, and inflammatory bowel disease. 2. **Cancer:** ALOX15 expression has been linked to cancer progression and metastasis, suggesting its potential as a therapeutic target. 3. **Neurological Disorders:** ALOX15-derived SPMs have been implicated in neurological disorders, such as multiple sclerosis and Alzheimer's disease, highlighting their potential as therapeutic targets. 4. **Regenerative Medicine:** ALOX15-derived SPMs have been shown to promote tissue repair and regeneration, making them potential therapeutic agents for regenerative medicine applications. In conclusion, the ALOX15 gene plays a crucial role in the production of SPMs that regulate inflammation and tissue repair. Its involvement in multiple physiological and pathological processes highlights its potential as a therapeutic target for various diseases. Further research is needed to fully elucidate the mechanisms of ALOX15 and its role in human disease.

Genular Protein ID: 1151080486

Symbol: LOX15_HUMAN

Name: Arachidonate 15-lipoxygenase

UniProtKB Accession Codes:

P16050 A8K2P4 B7ZA11 Q8N6R7 Q99657

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 86 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 5 DrugCentral 1 EC 3 EMBL 8 Ensembl 3 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 10 RefSeq 1 Rhea 54 SABIO-RK 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3202857

Title: Molecular cloning and primary structure of human 15-lipoxygenase.

PubMed ID: 3202857

DOI: 10.1016/s0006-291x(88)80271-7

PubMed ID: 9224951

Title: Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene.

PubMed ID: 9224951

DOI: 10.1016/s0167-4781(97)00005-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9700053

Title: Human 15-lipoxygenase gene promoter: analysis and identification of DNA binding sites for IL-13-induced regulatory factors in monocytes.

PubMed ID: 9700053

DOI: 10.1023/a:1006813009006

PubMed ID: 3356688

Title: Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases.

PubMed ID: 3356688

DOI: 10.1016/s0021-9258(18)60719-7

PubMed ID: 1662607

Title: Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes.

PubMed ID: 1662607

DOI: 10.1111/j.1432-1033.1991.tb16495.x

PubMed ID: 1944593

Title: A primary determinant for lipoxygenase positional specificity.

PubMed ID: 1944593

DOI: 10.1038/354149a0

PubMed ID: 8334154

Title: Overexpression, purification and characterization of human recombinant 15-lipoxygenase.

PubMed ID: 8334154

DOI: 10.1016/0005-2760(93)90085-n

PubMed ID: 9414270

Title: Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme.

PubMed ID: 9414270

PubMed ID: 11418015

Title: Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells.

PubMed ID: 11418015

DOI: 10.1054/plef.2001.0263

PubMed ID: 17052953

Title: Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity.

PubMed ID: 17052953

DOI: 10.1016/j.bbalip.2006.09.007

PubMed ID: 18755188

Title: Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.

PubMed ID: 18755188

DOI: 10.1016/j.febslet.2008.08.017

PubMed ID: 19528634

Title: 15(S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism.

PubMed ID: 19528634

DOI: 10.1194/jlr.m900081-jlr200

PubMed ID: 21831839

Title: 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells.

PubMed ID: 21831839

DOI: 10.1073/pnas.1018075108

PubMed ID: 23242647

Title: Biosynthesis, isolation, and NMR analysis of leukotriene A epoxides: substrate chirality as a determinant of the cis or trans epoxide configuration.

PubMed ID: 23242647

DOI: 10.1194/jlr.m033746

PubMed ID: 24282679

Title: Functional characterization of genetic enzyme variations in human lipoxygenases.

PubMed ID: 24282679

DOI: 10.1016/j.redox.2013.11.001

PubMed ID: 25293588

Title: Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.

PubMed ID: 25293588

DOI: 10.1194/jlr.m054072

PubMed ID: 32404334

Title: 15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5.

PubMed ID: 32404334

DOI: 10.1194/jlr.ra120000777

PubMed ID: 17959182

Title: A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease.

PubMed ID: 17959182

DOI: 10.1016/j.atherosclerosis.2007.09.003

Sequence Information:

  • Length: 662
  • Mass: 74804
  • Checksum: 9ACF7FE7863A045C
  • Sequence:
    • MGLYRIRVST GASLYAGSNN QVQLWLVGQH GEAALGKRLW PARGKETELK VEVPEYLGPL 
LFVKLRKRHL LKDDAWFCNW ISVQGPGAGD EVRFPCYRWV EGNGVLSLPE GTGRTVGEDP 
QGLFQKHREE ELEERRKLYR WGNWKDGLIL NMAGAKLYDL PVDERFLEDK RVDFEVSLAK 
GLADLAIKDS LNVLTCWKDL DDFNRIFWCG QSKLAERVRD SWKEDALFGY QFLNGANPVV 
LRRSAHLPAR LVFPPGMEEL QAQLEKELEG GTLFEADFSL LDGIKANVIL CSQQHLAAPL 
VMLKLQPDGK LLPMVIQLQL PRTGSPPPPL FLPTDPPMAW LLAKCWVRSS DFQLHELQSH 
LLRGHLMAEV IVVATMRCLP SIHPIFKLII PHLRYTLEIN VRARTGLVSD MGIFDQIMST 
GGGGHVQLLK QAGAFLTYSS FCPPDDLADR GLLGVKSSFY AQDALRLWEI IYRYVEGIVS 
LHYKTDVAVK DDPELQTWCR EITEIGLQGA QDRGFPVSLQ ARDQVCHFVT MCIFTCTGQH 
ASVHLGQLDW YSWVPNAPCT MRLPPPTTKD ATLETVMATL PNFHQASLQM SITWQLGRRQ 
PVMVAVGQHE EEYFSGPEPK AVLKKFREEL AALDKEIEIR NAKLDMPYEY LRPSVVENSV 
AI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.