Genular: Defining Cellular Identity and Function

Details for: Npy

Gene ID: 24604

Symbol: Npy

Ensembl ID: ENSRNOG00000046449

Description: neuropeptide Y

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Peptide ligand-binding receptors
(R-RNO-375276)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adult feeding behavior
(GO:0008343)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Central nervous system neuron development
(GO:0021954)
Cerebral cortex development
(GO:0021987)
Chemical synaptic transmission
(GO:0007268)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Feeding behavior
(GO:0007631)
Gaba-ergic synapse
(GO:0098982)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor binding
(GO:0001664)
Hormone activity
(GO:0005179)
Innate immune response
(GO:0045087)
Monocyte activation
(GO:0042117)
Negative regulation of acute inflammatory response to antigenic stimulus
(GO:0002865)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of somatostatin secretion
(GO:0090275)
Neuronal dense core vesicle
(GO:0098992)
Neuron projection development
(GO:0031175)
Neuropeptide hormone activity
(GO:0005184)
Neuropeptide signaling pathway
(GO:0007218)
Neuropeptide y receptor binding
(GO:0031841)
Perikaryon
(GO:0043204)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of appetite
(GO:0032100)
Positive regulation of cell-substrate adhesion
(GO:0010811)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dopamine metabolic process
(GO:0045964)
Positive regulation of eating behavior
(GO:1904000)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of nitric oxide metabolic process
(GO:1904407)
Positive regulation of somatostatin secretion
(GO:0090274)
Regulation of blood pressure
(GO:0008217)
Regulation of nerve growth factor production
(GO:0032903)
Regulation of presynaptic cytosolic calcium ion concentration
(GO:0099509)
Regulation of synaptic vesicle exocytosis
(GO:2000300)
Short-day photoperiodism
(GO:0048572)
Synaptic signaling via neuropeptide
(GO:0099538)
Terminal bouton
(GO:0043195)

Other Information

Proteins

Pro-neuropeptide Y

Genular Protein ID: 499444612

Symbol: NPY_RAT

Name: Pro-neuropeptide Y

UniProtKB Accession Codes:

P07808

Database IDs:

Citations:

PubMed ID: 3031687

Title: Molecular structure of mammalian neuropeptide Y: analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue.

PubMed ID: 3031687

DOI: 10.1073/pnas.84.8.2532

PubMed ID: 3031663

Title: Structure and expression of the rat neuropeptide Y gene.

PubMed ID: 3031663

DOI: 10.1073/pnas.84.7.2068

PubMed ID: 2834371

Title: Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.

PubMed ID: 2834371

DOI: 10.1016/s0021-9258(18)68784-8

PubMed ID: 3413293

Title: Isolation and sequence of rat peptide YY and neuropeptide Y.

PubMed ID: 3413293

DOI: 10.1016/0167-0115(88)90008-0

PubMed ID: 29166604

Title: Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4.

PubMed ID: 29166604

DOI: 10.1016/j.celrep.2017.10.084

PubMed ID: 30021165

Title: Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-alpha/TANC2 Recruits DCVs to Postsynaptic Sites.

PubMed ID: 30021165

DOI: 10.1016/j.celrep.2018.06.071

Sequence Information:

Length: 98
Mass: 11033
Checksum: E77EACEF3A3914B7
Sequence:

MMLGNKRMGL CGLTLALSLL VCLGILAEGY PSKPDNPGED APAEDMARYY SALRHYINLI 
TRQRYGKRSS PETLISDLLM RESTENAPRT RLEDPSMW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Npy

Associated with

Other Information

Molecular structure of mammalian neuropeptide Y: analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue. PubMed ID: 3031687

Structure and expression of the rat neuropeptide Y gene. PubMed ID: 3031663

Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester. PubMed ID: 2834371

Isolation and sequence of rat peptide YY and neuropeptide Y. PubMed ID: 3413293

Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4. PubMed ID: 29166604