Genular: Defining Cellular Identity and Function

Details for: Serpina1

Gene ID: 24648

Symbol: Serpina1

Ensembl ID: ENSRNOG00000032669

Description: serpin family A member 1

Associated with

Asparagine n-linked glycosylation
(R-RNO-446203)
Cargo concentration in the er
(R-RNO-5694530)
Copii-mediated vesicle transport
(R-RNO-204005)
Er to golgi anterograde transport
(R-RNO-199977)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Membrane trafficking
(R-RNO-199991)
Metabolism of proteins
(R-RNO-392499)
Neutrophil degranulation
(R-RNO-6798695)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet degranulation
(R-RNO-114608)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Response to elevated platelet cytosolic ca2+
(R-RNO-76005)
Transport to the golgi and subsequent modification
(R-RNO-948021)
Vesicle-mediated transport
(R-RNO-5653656)
Acute-phase response
(GO:0006953)
Endopeptidase inhibitor activity
(GO:0004866)
Endoplasmic reticulum
(GO:0005783)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Negative regulation of endopeptidase activity
(GO:0010951)
Protease binding
(GO:0002020)
Protein binding
(GO:0005515)
Response to chromate
(GO:0046687)
Response to cytokine
(GO:0034097)
Response to estradiol
(GO:0032355)
Response to hypoxia
(GO:0001666)
Response to inorganic substance
(GO:0010035)
Response to lead ion
(GO:0010288)
Response to lipopolysaccharide
(GO:0032496)
Response to methanol
(GO:0033986)
Response to organic cyclic compound
(GO:0014070)
Response to oxygen-containing compound
(GO:1901700)
Response to triglyceride
(GO:0034014)
Serine-type endopeptidase inhibitor activity
(GO:0004867)

Other Information

Proteins

Alpha-1-antiproteinase
A6JEP4_RAT

Genular Protein ID: 142792131

Symbol: A1AT_RAT

Name: Alpha-1-antiproteinase

UniProtKB Accession Codes:

P17475 Q6AYZ5

Database IDs:

Citations:

PubMed ID: 2229024

Title: Molecular cloning and sequencing of the cDNA of rat alpha 1-protease inhibitor and its expression in COS-1 cells.

PubMed ID: 2229024

DOI: 10.1093/oxfordjournals.jbchem.a123185

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2302382

Title: Molecular cloning and primary structure of rat alpha 1-antitrypsin.

PubMed ID: 2302382

DOI: 10.1021/bi00454a004

Sequence Information:

Length: 411
Mass: 46136
Checksum: B4245CFE21C5C761
Sequence:

MAPSISRGLL LLAALCCLAP SFLAEDAQET DTSQQDQSPT YRKISSNLAD FAFSLYRELV 
HQSNTSNIFF SPMSITTAFA MLSLGSKGDT RKQILEGLEF NLTQIPEADI HKAFHHLLQT 
LNRPDSELQL NTGNGLFVNK NLKLVEKFLE EVKNNYHSEA FSVNFADSEE AKKVINDYVE 
KGTQGKIVDL MKQLDEDTVF ALVNYIFFKG KWKRPFNPEH TRDADFHVDK STTVKVPMMN 
RLGMFDMHYC STLSSWVLMM DYLGNATAIF LLPDDGKMQH LEQTLTKDLI SRFLLNRQTR 
SAILYFPKLS ISGTYNLKTL LSSLGITRVF NNDADLSGIT EDAPLKLSQA VHKAVLTLDE 
RGTEAAGATV VEAVPMSLPP QVKFDHPFIF MIVESETQSP LFVGKVIDPT R

Genular Protein ID: 2234471123

Symbol: A6JEP4_RAT

Name: N/A

UniProtKB Accession Codes:

A6JEP4

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 411
Mass: 46122
Checksum: 31637D821BFCB87B
Sequence:

MAPSISRGLL LLAGLCCLAP SFLAEDAQET DTSQQDQSPT YRKISSNLAD FAFSLYRELV 
HQSNTSNIFF SPMSITTAFA MLSLGSKGDT RKQILEGLEF NLTQIPEADI HKAFHHLLQT 
LNRPDSELQL NTGNGLFVNK NLKLVEKFLE EVKNNYHSEA FSVNFADSEE AKKVINDYVE 
KGTQGKIVDL MKQLDEDTVF ALVNYIFFKG KWKRPFNPEH TRDADFHVDK STTVKVPMMN 
RLGMFDMHYC STLSSWVLMM DYLGNATAIF LLPDDGKMQH LEQTLTKDLI SRFLLNRQTR 
SAILYFPKLS ISGTYNLKTL LSSLGITRVF NNDADLSGIT EDAPLKLSQA VHKAVLTLDE 
RGTEAAGATV VEAVPMSLPP QVKFDHPFIF MIVESETQSP LFVGKVIDPT R

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Serpina1

Associated with

Other Information

Molecular cloning and sequencing of the cDNA of rat alpha 1-protease inhibitor and its expression in COS-1 cells. PubMed ID: 2229024

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular cloning and primary structure of rat alpha 1-antitrypsin. PubMed ID: 2302382

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Database document:

PubMed ID: 2229024

PubMed ID: 15489334

PubMed ID: 2302382

PubMed ID: 15632090