Genular: Defining Cellular Identity and Function

Details for: Ppm1a

Gene ID: 24666

Symbol: Ppm1a

Ensembl ID: ENSRNOG00000005916

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1A

Associated with

Downregulation of smad2/3:smad4 transcriptional activity
(R-RNO-2173795)
Energy dependent regulation of mtor by lkb1-ampk
(R-RNO-380972)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Mtor signalling
(R-RNO-165159)
Rna polymerase ii transcription
(R-RNO-73857)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Signal transduction
(R-RNO-162582)
Transcriptional activity of smad2/smad3:smad4 heterotrimer
(R-RNO-2173793)
Calmodulin-dependent protein phosphatase activity
(GO:0033192)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cytosol
(GO:0005829)
Dephosphorylation
(GO:0016311)
Magnesium ion binding
(GO:0000287)
Manganese ion binding
(GO:0030145)
Membrane
(GO:0016020)
Myosin phosphatase activity
(GO:0017018)
Negative regulation of bmp signaling pathway
(GO:0030514)
Negative regulation of canonical nf-kappab signal transduction
(GO:0043124)
Negative regulation of non-canonical nf-kappab signal transduction
(GO:1901223)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Neuron projection
(GO:0043005)
Nucleus
(GO:0005634)
Peptidyl-threonine dephosphorylation
(GO:0035970)
Phosphoprotein phosphatase activity
(GO:0004721)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of protein export from nucleus
(GO:0046827)
Protein binding
(GO:0005515)
Protein export from nucleus
(GO:0006611)
Protein serine/threonine phosphatase activity
(GO:0004722)
R-smad binding
(GO:0070412)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

Protein phosphatase 1A

Genular Protein ID: 1829692690

Symbol: PPM1A_RAT

Name: Protein phosphatase 1A

UniProtKB Accession Codes:

P20650

Database IDs:

Citations:

PubMed ID: 2538815

Title: Molecular cloning of rat type 2C (IA) protein phosphatase mRNA.

PubMed ID: 2538815

DOI: 10.1073/pnas.86.6.1796

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 382
Mass: 42417
Checksum: C1C386E935374F89
Sequence:

MGAFLDKPKM EKHNAQGQGN GLRYGLSSMQ GWRVEMEDAH TAVIGLPSGL ETWSFFAVYD 
GHAGSQVAKY CCEHLLDHIT NNQDFKGSAG APSVENVKNG IRTGFLEIDE HMRVMSEKKH 
GADRSGSTAV GVLISPQHTY FINCGDSRGL LCRNRKVHFF TQDHKPSNPL EKERIQNAGG 
SVMIQRVNGS LAVSRALGDF DYKCVHGKGP TEQLVSPEPE VHDIERSEED DQFIILACDG 
IWDVMGNEEL CDFVRSRLEV TDDLEKVCNE VVDTCLYKGS RDNMSVILIC FPNAPKVSAE 
AVKKEAELDK YLENRVEEII KKQGEGVPDL VHVMRTLASE NIPSLPPGGE LASKRNVIEA 
VYNRLNPYKN DDTDSASTDD MW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.