Genular: Defining Cellular Identity and Function

Details for: Ppp1ca

Gene ID: 24668

Symbol: Ppp1ca

Ensembl ID: ENSRNOG00000018708

Description: protein phosphatase 1 catalytic subunit alpha

Associated with

Darpp-32 events
(R-RNO-180024)
G alpha (i) signalling events
(R-RNO-418594)
Gpcr downstream signalling
(R-RNO-388396)
Opioid signalling
(R-RNO-111885)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Adherens junction
(GO:0005912)
Branching morphogenesis of an epithelial tube
(GO:0048754)
Cadherin binding involved in cell-cell adhesion
(GO:0098641)
Cell-cell adhesion
(GO:0098609)
Cell division
(GO:0051301)
Chromosome, telomeric region
(GO:0000781)
Circadian regulation of gene expression
(GO:0032922)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic spine
(GO:0043197)
Dephosphorylation
(GO:0016311)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Glutamatergic synapse
(GO:0098978)
Glycogen granule
(GO:0042587)
Glycogen metabolic process
(GO:0005977)
Lung development
(GO:0030324)
Metal ion binding
(GO:0046872)
Myosin phosphatase activity
(GO:0017018)
Neuronal cell body
(GO:0043025)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perikaryon
(GO:0043204)
Phosphatase activity
(GO:0016791)
Phosphoprotein phosphatase activity
(GO:0004721)
Plasma membrane
(GO:0005886)
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001241)
Postsynapse
(GO:0098794)
Presynapse
(GO:0098793)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein phosphatase 1 binding
(GO:0008157)
Protein phosphatase type 1 complex
(GO:0000164)
Protein serine/threonine phosphatase activity
(GO:0004722)
Ptw/pp1 phosphatase complex
(GO:0072357)
Regulation of circadian rhythm
(GO:0042752)
Regulation of glycogen biosynthetic process
(GO:0005979)
Regulation of glycogen catabolic process
(GO:0005981)
Response to lead ion
(GO:0010288)
Rhythmic process
(GO:0048511)
Ribonucleoprotein complex binding
(GO:0043021)

Other Information

Proteins

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Genular Protein ID: 2840077394

Symbol: PP1A_RAT

Name: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

UniProtKB Accession Codes:

P62138 P08129 P20653 P22802

Database IDs:

Citations:

PubMed ID: 1650776

Title: Molecular cloning and sequence analysis of cDNA for the catalytic subunit 1 alpha of rat kidney type 1 protein phosphatase, and detection of the gene expression at high levels in hepatoma cells and regenerating livers as compared to rat livers.

PubMed ID: 1650776

PubMed ID: 2177460

Title: Identification of members of the protein phosphatase 1 gene family in the rat and enhanced expression of protein phosphatase 1 alpha gene in rat hepatocellular carcinomas.

PubMed ID: 2177460

DOI: 10.1111/j.1349-7006.1990.tb02690.x

PubMed ID: 7751917

Title: Differential expression of protein phosphatase 1 isoforms in mammalian brain.

PubMed ID: 7751917

DOI: 10.1523/jneurosci.15-05-03375.1995

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10504266

Title: Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.

PubMed ID: 10504266

DOI: 10.1021/bi991227d

PubMed ID: 17890166

Title: The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.

PubMed ID: 17890166

DOI: 10.1016/j.bbapap.2007.07.015

Sequence Information:

Length: 330
Mass: 37512
Checksum: 60C37E1AD9831DAC
Sequence:

MSDSEKLNLD SIIGRLLEVQ GSRPGKNVQL TENEIRGLCL KSREIFLSQP ILLELEAPLK 
ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL 
LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL 
QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVQGWGEND RGVSFTFGAE VVAKFLHKHD 
LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAD 
KNKGKYGQFS GLNPGGRPIT PPRNSAKAKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ppp1ca

Associated with

Other Information

Molecular cloning and sequence analysis of cDNA for the catalytic subunit 1 alpha of rat kidney type 1 protein phosphatase, and detection of the gene expression at high levels in hepatoma cells and regenerating livers as compared to rat livers. PubMed ID: 1650776

Identification of members of the protein phosphatase 1 gene family in the rat and enhanced expression of protein phosphatase 1 alpha gene in rat hepatocellular carcinomas. PubMed ID: 2177460

Differential expression of protein phosphatase 1 isoforms in mammalian brain. PubMed ID: 7751917

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. PubMed ID: 10504266