Genular: Defining Cellular Identity and Function

Details for: Ppp2ca

Gene ID: 24672

Symbol: Ppp2ca

Ensembl ID: ENSRNOG00000005389

Description: protein phosphatase 2 catalytic subunit alpha

Associated with

Adaptive immune system
(R-RNO-1280218)
Amplification of signal from the kinetochores
(R-RNO-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-RNO-141444)
Antiviral mechanism by ifn-stimulated genes
(R-RNO-1169410)
Beta-catenin phosphorylation cascade
(R-RNO-196299)
Cell cycle
(R-RNO-1640170)
Cell cycle, mitotic
(R-RNO-69278)
Cell cycle checkpoints
(R-RNO-69620)
Costimulation by the cd28 family
(R-RNO-388841)
Ctla4 inhibitory signaling
(R-RNO-389513)
Cyclin a/b1/b2 associated events during g2/m transition
(R-RNO-69273)
Cyclin d associated events in g1
(R-RNO-69231)
Cytokine signaling in immune system
(R-RNO-1280215)
Darpp-32 events
(R-RNO-180024)
Degradation of beta-catenin by the destruction complex
(R-RNO-195253)
Disassembly of the destruction complex and recruitment of axin to the membrane
(R-RNO-4641262)
E2f mediated regulation of dna replication
(R-RNO-113510)
Eml4 and nudc in mitotic spindle formation
(R-RNO-9648025)
G1 phase
(R-RNO-69236)
G1/s transition
(R-RNO-69206)
G2/m transition
(R-RNO-69275)
G alpha (i) signalling events
(R-RNO-418594)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Gpcr downstream signalling
(R-RNO-388396)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Inhibition of replication initiation of damaged dna by rb1/e2f1
(R-RNO-113501)
Innate immune system
(R-RNO-168249)
Interferon signaling
(R-RNO-913531)
Interleukin-17 signaling
(R-RNO-448424)
Intracellular signaling by second messengers
(R-RNO-9006925)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Metabolism of rna
(R-RNO-8953854)
Mitotic anaphase
(R-RNO-68882)
Mitotic g1 phase and g1/s transition
(R-RNO-453279)
Mitotic g2-g2/m phases
(R-RNO-453274)
Mitotic metaphase and anaphase
(R-RNO-2555396)
Mitotic prometaphase
(R-RNO-68877)
Mitotic spindle checkpoint
(R-RNO-69618)
M phase
(R-RNO-68886)
Myd88 cascade initiated on plasma membrane
(R-RNO-975871)
Myd88 dependent cascade initiated on endosome
(R-RNO-975155)
Myd88-independent tlr4 cascade
(R-RNO-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-RNO-166058)
Negative regulation of fgfr1 signaling
(R-RNO-5654726)
Negative regulation of fgfr2 signaling
(R-RNO-5654727)
Negative regulation of fgfr3 signaling
(R-RNO-5654732)
Negative regulation of fgfr4 signaling
(R-RNO-5654733)
Negative regulation of mapk pathway
(R-RNO-5675221)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Nonsense-mediated decay (nmd)
(R-RNO-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-RNO-975957)
Nuclear envelope (ne) reassembly
(R-RNO-2995410)
Nuclear events (kinase and transcription factor activation)
(R-RNO-198725)
Opioid signalling
(R-RNO-111885)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Pkr-mediated signaling
(R-RNO-9833482)
Platelet homeostasis
(R-RNO-418346)
Platelet sensitization by ldl
(R-RNO-432142)
Raf/map kinase cascade
(R-RNO-5673001)
Raf activation
(R-RNO-5673000)
Regulation of tp53 activity
(R-RNO-5633007)
Regulation of tp53 expression and degradation
(R-RNO-6806003)
Resolution of sister chromatid cohesion
(R-RNO-2500257)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate formins
(R-RNO-5663220)
Rna polymerase ii transcription
(R-RNO-73857)
Separation of sister chromatids
(R-RNO-2467813)
Signaling by fgfr
(R-RNO-190236)
Signaling by fgfr1
(R-RNO-5654736)
Signaling by fgfr2
(R-RNO-5654738)
Signaling by fgfr3
(R-RNO-5654741)
Signaling by fgfr4
(R-RNO-5654743)
Signaling by gpcr
(R-RNO-372790)
Signaling by interleukins
(R-RNO-449147)
Signaling by ntrk1 (trka)
(R-RNO-187037)
Signaling by ntrks
(R-RNO-166520)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signaling by wnt
(R-RNO-195721)
Signal transduction
(R-RNO-162582)
Spry regulation of fgf signaling
(R-RNO-1295596)
Tcf dependent signaling in response to wnt
(R-RNO-201681)
Toll-like receptor cascades
(R-RNO-168898)
Toll like receptor 2 (tlr2) cascade
(R-RNO-181438)
Toll like receptor 3 (tlr3) cascade
(R-RNO-168164)
Toll like receptor 4 (tlr4) cascade
(R-RNO-166016)
Toll like receptor 5 (tlr5) cascade
(R-RNO-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-RNO-168181)
Toll like receptor 9 (tlr9) cascade
(R-RNO-168138)
Toll like receptor 10 (tlr10) cascade
(R-RNO-168142)
Toll like receptor tlr1:tlr2 cascade
(R-RNO-168179)
Toll like receptor tlr6:tlr2 cascade
(R-RNO-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-RNO-975138)
Transcriptional regulation by tp53
(R-RNO-3700989)
Trif(ticam1)-mediated tlr4 signaling
(R-RNO-937061)

Other Information

Proteins

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Genular Protein ID: 2567509557

Symbol: PP2AA_RAT

Name: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

UniProtKB Accession Codes:

P63331 O88591 P13353

Database IDs:

Citations:

PubMed ID: 2554255

Title: Nucleotide sequence of a rat heart cDNA encoding the isotype alpha of the catalytic subunit of protein phosphatase 2A.

PubMed ID: 2554255

DOI: 10.1093/nar/17.20.8369

PubMed ID: 2461222

Title: Molecular cloning of cDNA for the catalytic subunit of rat liver type 2A protein phosphatase, and detection of high levels of expression of the gene in normal and cancer cells.

PubMed ID: 2461222

DOI: 10.1016/0167-4781(88)90032-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 309
Mass: 35608
Checksum: 8DC11276E6DF9E33
Sequence:

MDEKLFTKEL DQWIEQLNEC KQLSESQVKS LCEKAKEILT KESNVQEVRC PVTVCGDVHG 
QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYRER ITILRGNHES 
RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL SPSIDTLDHI 
RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA 
HQLVMEGYNW CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV 
TRRTPDYFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.