Genular: Defining Cellular Identity and Function

Details for: Ppp3cb

Gene ID: 24675

Symbol: Ppp3cb

Ensembl ID: ENSRNOG00000054782

Description: protein phosphatase 3 catalytic subunit beta

Associated with

Calcineurin-mediated signaling
(GO:0097720)
Calcineurin-nfat signaling cascade
(GO:0033173)
Calcineurin complex
(GO:0005955)
Calcium-dependent protein serine/threonine phosphatase activity
(GO:0004723)
Calcium-ion regulated exocytosis
(GO:0017156)
Calcium ion binding
(GO:0005509)
Calmodulin-dependent protein phosphatase activity
(GO:0033192)
Calmodulin binding
(GO:0005516)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Glutamatergic synapse
(GO:0098978)
Heart development
(GO:0007507)
Locomotion involved in locomotory behavior
(GO:0031987)
Lymphangiogenesis
(GO:0001946)
Metal ion binding
(GO:0046872)
Muscle cell cellular homeostasis
(GO:0046716)
Myosin phosphatase activity
(GO:0017018)
Negative regulation of signaling
(GO:0023057)
Negative regulation of t cell mediated cytotoxicity
(GO:0001915)
Plasma membrane
(GO:0005886)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of lysosome organization
(GO:1905673)
Positive regulation of protein localization to nucleus
(GO:1900182)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein phosphatase 2b binding
(GO:0030346)
Protein serine/threonine phosphatase activity
(GO:0004722)
Regulation of gene expression
(GO:0010468)
Regulation of insulin secretion
(GO:0050796)
Regulation of synaptic vesicle endocytosis
(GO:1900242)
Response to amphetamine
(GO:0001975)
Response to cytokine
(GO:0034097)
Skeletal muscle fiber development
(GO:0048741)
Synapse
(GO:0045202)
T-tubule
(GO:0030315)
T cell differentiation
(GO:0030217)
T cell homeostasis
(GO:0043029)
T cell mediated cytotoxicity
(GO:0001913)
Z disc
(GO:0030018)

Other Information

Proteins

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

Genular Protein ID: 1528656765

Symbol: PP2BB_RAT

Name: Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

UniProtKB Accession Codes:

P20651 Q6LDJ7

Database IDs:

Citations:

PubMed ID: 2558657

Title: Evidence for a second isoform of the catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A).

PubMed ID: 2558657

DOI: 10.1016/0006-291x(89)92752-6

PubMed ID: 2174876

Title: Multiplicity of protein serine-threonine phosphatases in PC12 pheochromocytoma and FTO-2B hepatoma cells.

PubMed ID: 2174876

DOI: 10.1016/s0021-9258(18)45767-5

PubMed ID: 23699505

Title: Balance of calcineurin Aalpha and CDK5 activities sets release probability at nerve terminals.

PubMed ID: 23699505

DOI: 10.1523/jneurosci.4288-12.2013

PubMed ID: 25967121

Title: Calcineurin and sorting-related receptor with A-type repeats interact to regulate the renal Na(+)-K(+)-2Cl(-) cotransporter.

PubMed ID: 25967121

DOI: 10.1681/asn.2014070728

Sequence Information:

Length: 525
Mass: 59113
Checksum: 5E66AF3100BE3987
Sequence:

MAAPEPARAA PPPPPPPPPP LGADRVVKAV PFPPTHRLTS EEVFDMDGIP RVDVLKNHLV 
KEGRVDEEIA LRIINEGAAI LRREKTMIEV EAPITVCGDI HGQFFDLMKL FEVGGSPANT 
RYLFLGDYVD RGYFSIECVL YLWVLKILYP STLFLLRGNH ECRHLTEYFT FKQECKIKYS 
ERVYEACMEA FDSLPLAALL NQQFLCVHGG LSPEIHTLDD IRRLDRFKEP PAFGPMCDLL 
WSDPSEDFGN EKSQEHFSHN TVRGCSYFYN YPAVCEFLQN NNLLSIIRAH EAQDAGYRMY 
RKSQTTGFPS LITIFSAPNY LDVYNNKAAV LKYENNVMNI RQFNCSPHPY WLPNFMDVFT 
WSLPFVGEKV TEMLVNVLSI CSDDELMTEG EDQFDVGSAA ARKEIIRNKI RAIGKMARVF 
SVLREESESV LTLKGLTPTG MLPSGVLAGG RQTLQSATVE AIEAEKAIRG SSPPHRICSF 
EEAKGLDRIN ERMPPRKDAV QQDGFNSLNT AHTTENHGTG NHSAQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ppp3cb

Associated with

Other Information

Evidence for a second isoform of the catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A). PubMed ID: 2558657

Multiplicity of protein serine-threonine phosphatases in PC12 pheochromocytoma and FTO-2B hepatoma cells. PubMed ID: 2174876

Balance of calcineurin Aalpha and CDK5 activities sets release probability at nerve terminals. PubMed ID: 23699505

Calcineurin and sorting-related receptor with A-type repeats interact to regulate the renal Na(+)-K(+)-2Cl(-) cotransporter. PubMed ID: 25967121

Database document:

PubMed ID: 2558657

PubMed ID: 2174876

PubMed ID: 23699505

PubMed ID: 25967121