Genular: Defining Cellular Identity and Function

Details for: Prkar2b

Gene ID: 24679

Symbol: Prkar2b

Ensembl ID: ENSRNOG00000009079

Description: protein kinase cAMP-dependent type II regulatory subunit beta

Associated with

Activation of nmda receptors and postsynaptic events
(R-RNO-442755)
Anchoring of the basal body to the plasma membrane
(R-RNO-5620912)
Aquaporin-mediated transport
(R-RNO-445717)
Aurka activation by tpx2
(R-RNO-8854518)
Ca-dependent events
(R-RNO-111996)
Calmodulin induced events
(R-RNO-111933)
Cam pathway
(R-RNO-111997)
Cell cycle
(R-RNO-1640170)
Cell cycle, mitotic
(R-RNO-69278)
Centrosome maturation
(R-RNO-380287)
Cilium assembly
(R-RNO-5617833)
Creb1 phosphorylation through the activation of adenylate cyclase
(R-RNO-442720)
Dag and ip3 signaling
(R-RNO-1489509)
Darpp-32 events
(R-RNO-180024)
Factors involved in megakaryocyte development and platelet production
(R-RNO-983231)
G-protein mediated events
(R-RNO-112040)
G2/m transition
(R-RNO-69275)
G alpha (i) signalling events
(R-RNO-418594)
G alpha (s) signalling events
(R-RNO-418555)
Glucagon signaling in metabolic regulation
(R-RNO-163359)
Gpcr downstream signalling
(R-RNO-388396)
Gper1 signaling
(R-RNO-9634597)
Hedgehog 'off' state
(R-RNO-5610787)
Hemostasis
(R-RNO-109582)
Integration of energy metabolism
(R-RNO-163685)
Intracellular signaling by second messengers
(R-RNO-9006925)
Loss of nlp from mitotic centrosomes
(R-RNO-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-RNO-380284)
Metabolism
(R-RNO-1430728)
Mitotic g2-g2/m phases
(R-RNO-453274)
Mitotic prometaphase
(R-RNO-68877)
M phase
(R-RNO-68886)
Neuronal system
(R-RNO-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-RNO-112314)
Opioid signalling
(R-RNO-111885)
Organelle biogenesis and maintenance
(R-RNO-1852241)
Pka-mediated phosphorylation of creb
(R-RNO-111931)
Pka activation
(R-RNO-163615)
Pka activation in glucagon signalling
(R-RNO-164378)
Plc beta mediated events
(R-RNO-112043)
Post nmda receptor activation events
(R-RNO-438064)
Recruitment of mitotic centrosome proteins and complexes
(R-RNO-380270)
Recruitment of numa to mitotic centrosomes
(R-RNO-380320)
Regulation of plk1 activity at g2/m transition
(R-RNO-2565942)
Signaling by gpcr
(R-RNO-372790)
Signaling by hedgehog
(R-RNO-5358351)
Signal transduction
(R-RNO-162582)
Transmission across chemical synapses
(R-RNO-112315)
Transport of small molecules
(R-RNO-382551)
Vasopressin regulates renal water homeostasis via aquaporins
(R-RNO-432040)
Camp-dependent protein kinase complex
(GO:0005952)
Camp-dependent protein kinase inhibitor activity
(GO:0004862)
Camp-dependent protein kinase regulator activity
(GO:0008603)
Camp binding
(GO:0030552)
Centrosome
(GO:0005813)
Ciliary base
(GO:0097546)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Dendritic shaft
(GO:0043198)
Dendritic spine
(GO:0043197)
Fatty acid metabolic process
(GO:0006631)
Glutamatergic synapse
(GO:0098978)
Kinase activity
(GO:0016301)
Learning
(GO:0007612)
Modulation of chemical synaptic transmission
(GO:0050804)
Negative regulation of camp-dependent protein kinase activity
(GO:2000480)
Neuronal cell body
(GO:0043025)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Postsynapse
(GO:0098794)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein kinase a catalytic subunit binding
(GO:0034236)
Protein kinase binding
(GO:0019901)
Regulation of protein phosphorylation
(GO:0001932)
Response to antipsychotic drug
(GO:0097332)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

cAMP-dependent protein kinase type II-beta regulatory subunit

Genular Protein ID: 4008710895

Symbol: KAP3_RAT

Name: cAMP-dependent protein kinase type II-beta regulatory subunit

UniProtKB Accession Codes:

P12369

Database IDs:

Citations:

PubMed ID: 3401231

Title: Molecular cloning, cDNA structure and deduced amino acid sequence for the hormone-induced regulatory subunit (RII beta) of cAMP-dependent protein kinase from rat ovarian granulosa cells.

PubMed ID: 3401231

DOI: 10.1016/0006-291x(88)90197-0

PubMed ID: 2427518

Title: Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells.

PubMed ID: 2427518

DOI: 10.1016/s0021-9258(18)67247-3

PubMed ID: 16641100

Title: Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.

PubMed ID: 16641100

DOI: 10.1073/pnas.0600895103

PubMed ID: 21423175

Title: Control of PKA stability and signalling by the RING ligase praja2.

PubMed ID: 21423175

DOI: 10.1038/ncb2209

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 11342137

Title: Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.

PubMed ID: 11342137

DOI: 10.1016/s0969-2126(00)00556-6

Sequence Information:

Length: 416
Mass: 46123
Checksum: 8BC984E325FA3612
Sequence:

MSIEIPAGLT ELLQGFTVEV LRHQPADLLE FALQHFTRLQ QENERKGAAR FGHEGRTWGD 
AGAAAGGGTP SKGVNFAEEP MRSDSENGEE EEAAEAGAFN APVINRFTRR ASVCAEAYNP 
DEEEDDAESR IIHPKTDDQR NRLQEACKDI LLFKNLDPEQ MSQVLDAMFE KLVKEGEHVI 
DQGDDGDNFY VIDRGTFDIY VKCDGVGRCV GNYDNRGSFG ELALMYNTPR AATITATSPG 
ALWGLDRVTF RRIIVKNNAK KRKMYESFIE SLPFLKSLEV SERLKVVDVI GTKVYNDGEQ 
IIAQGDSADS FFIVESGEVR ITMKRKGKSD IEENGAVEIA RCLRGQYFGE LALVTNKPRA 
ASAHAIGTVK CLAMDVQAFE RLLGPCMEIM KRNIATYEEQ LVALFGTNMD IVEPTA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prkar2b

Associated with

Other Information

Molecular cloning, cDNA structure and deduced amino acid sequence for the hormone-induced regulatory subunit (RII beta) of cAMP-dependent protein kinase from rat ovarian granulosa cells. PubMed ID: 3401231

Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells. PubMed ID: 2427518

Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. PubMed ID: 16641100

Control of PKA stability and signalling by the RING ligase praja2. PubMed ID: 21423175

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903