Genular: Defining Cellular Identity and Function

Details for: Prl

Gene ID: 24683

Symbol: Prl

Ensembl ID: ENSRNOG00000017374

Description: prolactin

Associated with

Cell population proliferation
(GO:0008283)
Cellular response to hormone stimulus
(GO:0032870)
Cellular response to hypoxia
(GO:0071456)
Circadian rhythm
(GO:0007623)
Epithelial cell proliferation
(GO:0050673)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Female pregnancy
(GO:0007565)
Hormone activity
(GO:0005179)
Lactation
(GO:0007595)
Mammary gland development
(GO:0030879)
Maternal behavior
(GO:0042711)
Metal ion binding
(GO:0046872)
Multicellular organismal response to stress
(GO:0033555)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of estrogen biosynthetic process
(GO:1904077)
Negative regulation of hydrogen peroxide biosynthetic process
(GO:0010730)
Negative regulation of nitric oxide biosynthetic process
(GO:0045019)
Negative regulation of progesterone biosynthetic process
(GO:2000183)
Ovulation cycle
(GO:0042698)
Parturition
(GO:0007567)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of lactation
(GO:1903489)
Positive regulation of mirna transcription
(GO:1902895)
Positive regulation of receptor signaling pathway via jak-stat
(GO:0046427)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Prolactin receptor binding
(GO:0005148)
Prolactin signaling pathway
(GO:0038161)
Regulation of ossification
(GO:0030278)
Regulation of receptor signaling pathway via jak-stat
(GO:0046425)
Response to estradiol
(GO:0032355)
Response to ethanol
(GO:0045471)
Response to lipopolysaccharide
(GO:0032496)
Response to macrophage colony-stimulating factor
(GO:0036005)
Response to nutrient
(GO:0007584)
Response to nutrient levels
(GO:0031667)
Response to organic cyclic compound
(GO:0014070)
Response to xenobiotic stimulus
(GO:0009410)
Secretory granule
(GO:0030141)
Signal transduction
(GO:0007165)

Other Information

Proteins

Prolactin
B2RYT1_RAT

Genular Protein ID: 1335072350

Symbol: PRL_RAT

Name: Prolactin

UniProtKB Accession Codes:

P01237 P70520

Database IDs:

Citations:

PubMed ID: 6283362

Title: Structural analysis of the prolactin gene suggests a separate origin for its 5' end.

PubMed ID: 6283362

DOI: 10.1038/297603a0

PubMed ID: 6251061

Title: Structure of the rat prolactin gene.

PubMed ID: 6251061

DOI: 10.1016/s0021-9258(18)43550-8

PubMed ID: 6993473

Title: Structure of cloned DNA complementary to rat prolactin messenger RNA.

PubMed ID: 6993473

DOI: 10.1016/s0021-9258(18)43768-4

PubMed ID: 728396

Title: Complete amino acid sequence of the precursor region of rat prolactin.

PubMed ID: 728396

DOI: 10.1021/bi00617a022

PubMed ID: 925136

Title: Human pituitary prolactin (hPRL): the entire linear amino acid sequence.

PubMed ID: 925136

DOI: 10.1210/jcem-45-5-1112

Sequence Information:

Length: 226
Mass: 25753
Checksum: 755E2874A26862C7
Sequence:

MNSQVSARKA GTLLLLMMSN LLFCQNVQTL PVCSGGDCQT PLPELFDRVV MLSHYIHTLY 
TDMFIEFDKQ YVQDREFIAK AINDCPTSSL ATPEDKEQAQ KVPPEVLLNL ILSLVHSWND 
PLFQLITGLG GIHEAPDAII SRAKEIEEQN KRLLEGIEKI ISQAYPEAKG NEIYLVWSQL 
PSLQGVDEES KDLAFYNNIR CLRRDSHKVD NYLKFLRCQI VHKNNC

Genular Protein ID: 900392542

Symbol: B2RYT1_RAT

Name: N/A

UniProtKB Accession Codes:

B2RYT1

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 225
Mass: 25682
Checksum: 278FCBCA9E6DEE01
Sequence:

MNSQVSARKG TLLLLMMSNL LFCQNVQTLP VCSGGDCQTP LPELFDRVVM LSHYIHTLYT 
DMFIEFDKQY VQDREFIAKA INDCPTSSLA TPEDKEQAQK VPPEVLLNLI LSLVHSWNDP 
LFQLITGLGG IHEAPDAIIS RAKEIEEQNK RLLEGIEKII SQAYPEAKGN EIYLVWSQLP 
SLQGVDEESK DLAFYNNIRC LRRDSHKVDN YLKFLRCQIV HKNNC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prl

Associated with

Other Information

Structural analysis of the prolactin gene suggests a separate origin for its 5' end. PubMed ID: 6283362

Structure of the rat prolactin gene. PubMed ID: 6251061

Structure of cloned DNA complementary to rat prolactin messenger RNA. PubMed ID: 6993473

Complete amino acid sequence of the precursor region of rat prolactin. PubMed ID: 728396

Human pituitary prolactin (hPRL): the entire linear amino acid sequence. PubMed ID: 925136