Details for: ALOX15B

Gene ID: 247

Symbol: ALOX15B

Ensembl ID: ENSG00000179593

Description: arachidonate 15-lipoxygenase type B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 32.1128
    Cell Significance Index: -5.0000
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 28.6594
    Cell Significance Index: 37.0800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 18.8454
    Cell Significance Index: -4.7800
  • Cell Name: epithelial cell of sweat gland (CL1000448)
    Fold Change: 7.9058
    Cell Significance Index: 5.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.0066
    Cell Significance Index: -4.9400
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 2.9114
    Cell Significance Index: 7.6800
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 0.5771
    Cell Significance Index: 9.9200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.5695
    Cell Significance Index: 7.7700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.4647
    Cell Significance Index: 2.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3923
    Cell Significance Index: 10.9600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.2743
    Cell Significance Index: 3.8500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1816
    Cell Significance Index: 2.5900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.1556
    Cell Significance Index: 1.6100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1242
    Cell Significance Index: 9.2600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0837
    Cell Significance Index: 63.3400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0734
    Cell Significance Index: 7.2600
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: 0.0629
    Cell Significance Index: 0.5200
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.0326
    Cell Significance Index: 0.4200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0298
    Cell Significance Index: 2.1100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0297
    Cell Significance Index: 1.3500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0287
    Cell Significance Index: 0.4600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0233
    Cell Significance Index: 21.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0207
    Cell Significance Index: 2.1100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0196
    Cell Significance Index: 0.3300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0136
    Cell Significance Index: 2.2200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0107
    Cell Significance Index: 3.0800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0105
    Cell Significance Index: 4.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0031
    Cell Significance Index: 0.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0013
    Cell Significance Index: -0.2700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0021
    Cell Significance Index: -3.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0036
    Cell Significance Index: -6.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0037
    Cell Significance Index: -5.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0052
    Cell Significance Index: -7.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0057
    Cell Significance Index: -3.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0070
    Cell Significance Index: -3.8500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0071
    Cell Significance Index: -5.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0091
    Cell Significance Index: -5.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0095
    Cell Significance Index: -3.3900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0101
    Cell Significance Index: -0.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0105
    Cell Significance Index: -4.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0125
    Cell Significance Index: -2.2600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0179
    Cell Significance Index: -0.7300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0184
    Cell Significance Index: -0.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0206
    Cell Significance Index: -2.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0219
    Cell Significance Index: -3.1900
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0240
    Cell Significance Index: -0.3500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0257
    Cell Significance Index: -2.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0311
    Cell Significance Index: -5.3100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0315
    Cell Significance Index: -4.0700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0318
    Cell Significance Index: -6.6900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0337
    Cell Significance Index: -4.6300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0361
    Cell Significance Index: -1.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0441
    Cell Significance Index: -2.2900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0457
    Cell Significance Index: -2.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0459
    Cell Significance Index: -5.2600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0469
    Cell Significance Index: -2.0400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0469
    Cell Significance Index: -1.3500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0479
    Cell Significance Index: -4.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0498
    Cell Significance Index: -1.0600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0568
    Cell Significance Index: -1.0500
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0572
    Cell Significance Index: -0.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0578
    Cell Significance Index: -2.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0578
    Cell Significance Index: -1.8500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0629
    Cell Significance Index: -4.0600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0669
    Cell Significance Index: -1.7200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0683
    Cell Significance Index: -5.2400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0685
    Cell Significance Index: -1.6600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0754
    Cell Significance Index: -5.0700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.0766
    Cell Significance Index: -0.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0784
    Cell Significance Index: -4.8200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0820
    Cell Significance Index: -3.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0920
    Cell Significance Index: -4.8300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0933
    Cell Significance Index: -2.3300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0981
    Cell Significance Index: -3.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1009
    Cell Significance Index: -5.6600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1032
    Cell Significance Index: -3.3800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1061
    Cell Significance Index: -3.3800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1133
    Cell Significance Index: -3.0300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1137
    Cell Significance Index: -3.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1145
    Cell Significance Index: -5.3400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1163
    Cell Significance Index: -1.4700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1171
    Cell Significance Index: -3.4500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1173
    Cell Significance Index: -5.1900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1198
    Cell Significance Index: -1.7400
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1223
    Cell Significance Index: -1.6300
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.1293
    Cell Significance Index: -1.6000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1319
    Cell Significance Index: -3.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1373
    Cell Significance Index: -5.2000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1393
    Cell Significance Index: -3.4800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1427
    Cell Significance Index: -4.1900
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.1430
    Cell Significance Index: -1.6900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1508
    Cell Significance Index: -3.7600
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1514
    Cell Significance Index: -2.9600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1598
    Cell Significance Index: -4.5600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1641
    Cell Significance Index: -2.3500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1644
    Cell Significance Index: -3.6000
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1657
    Cell Significance Index: -2.1000
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.1666
    Cell Significance Index: -2.0100
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: -0.1671
    Cell Significance Index: -2.0200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1694
    Cell Significance Index: -3.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ALOX15B is a type B lipoxygenase enzyme that exhibits distinct substrate specificity, primarily catalyzing the conversion of arachidonic acid into 15-ETE. This enzyme is highly expressed in various tissues, including the lung, colon, skin, and brain, where it plays a crucial role in regulating immune responses and lipid metabolism. ALOX15B is also involved in the biosynthesis of other eicosanoids, such as lipoxins and hepoxilins, which have anti-inflammatory and pro-resolving properties. **Pathways and Functions:** ALOX15B is integral to several signaling pathways, including the endocannabinoid, cytokine, and chemokine pathways. The enzyme's activity is tightly regulated by various post-translational modifications, which control its substrate specificity and enzymatic activity. ALOX15B's functions can be broadly categorized into the following: 1. **Immune regulation:** ALOX15B produces 15-ETE, which has anti-inflammatory and pro-resolving properties, modulating immune responses in various tissues. 2. **Lipid metabolism:** The enzyme regulates the metabolism of arachidonic acid, a polyunsaturated fatty acid, into 15-ETE and other eicosanoids. 3. **Cell differentiation and proliferation:** ALOX15B influences cell differentiation, proliferation, and migration by regulating the expression of key transcription factors and growth factors. 4. **Cytoskeletal organization:** The enzyme's activity affects cytoskeletal organization and cell adhesion, influencing cellular processes such as migration and invasion. **Clinical Significance:** Dysregulation of ALOX15B has been implicated in various diseases, including: 1. **Asthma and COPD:** Altered expression of ALOX15B has been linked to airway inflammation and remodeling in asthma and COPD. 2. **Cancer:** The enzyme's activity has been associated with cancer progression, metastasis, and resistance to chemotherapy. 3. **Neurological disorders:** ALOX15B has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's. 4. **Cardiovascular disease:** The enzyme's activity has been linked to atherosclerosis and cardiovascular disease. In conclusion, ALOX15B is a critical regulator of lipid metabolism and immune responses, playing a pivotal role in various cellular processes. Understanding the mechanisms of ALOX15B's action and its clinical significance can provide valuable insights into the development of novel therapeutic strategies for diseases characterized by dysregulation of this enzyme.

Genular Protein ID: 2437987847

Symbol: LX15B_HUMAN

Name: Arachidonate 15-lipoxygenase B

UniProtKB Accession Codes:

O15296 D3DTR2 Q8IYQ2 Q8TEV3 Q8TEV4 Q8TEV5 Q8TEV6 Q9UKM4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 76 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 1 EMBL 15 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 36 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 1 RefSeq 3 Rhea 42 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 3 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9177185

Title: Discovery of a second 15S-lipoxygenase in humans.

PubMed ID: 9177185

DOI: 10.1073/pnas.94.12.6148

PubMed ID: 11350124

Title: A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression.

PubMed ID: 11350124

DOI: 10.1006/geno.2001.6519

PubMed ID: 11839751

Title: Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells.

PubMed ID: 11839751

DOI: 10.1074/jbc.m111936200

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10542053

Title: Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase.

PubMed ID: 10542053

DOI: 10.1046/j.1432-1327.1999.00818.x

PubMed ID: 10625675

Title: Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2.

PubMed ID: 10625675

DOI: 10.1074/jbc.275.2.1287

PubMed ID: 11956198

Title: 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist.

PubMed ID: 11956198

DOI: 10.1074/jbc.m201084200

PubMed ID: 12704195

Title: Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants.

PubMed ID: 12704195

DOI: 10.1074/jbc.m301920200

PubMed ID: 16112079

Title: Double dioxygenation by mouse 8S-lipoxygenase: specific formation of a potent peroxisome proliferator-activated receptor alpha agonist.

PubMed ID: 16112079

DOI: 10.1016/j.bbrc.2005.08.029

PubMed ID: 17493578

Title: Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases.

PubMed ID: 17493578

DOI: 10.1016/j.abb.2007.04.007

PubMed ID: 18067895

Title: 15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration.

PubMed ID: 18067895

DOI: 10.1016/j.atherosclerosis.2007.10.027

PubMed ID: 18311922

Title: Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.

PubMed ID: 18311922

DOI: 10.1021/bi702530z

PubMed ID: 18755188

Title: Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.

PubMed ID: 18755188

DOI: 10.1016/j.febslet.2008.08.017

PubMed ID: 22912809

Title: Arachidonate 15-lipoxygenase type B knockdown leads to reduced lipid accumulation and inflammation in atherosclerosis.

PubMed ID: 22912809

DOI: 10.1371/journal.pone.0043142

PubMed ID: 24282679

Title: Functional characterization of genetic enzyme variations in human lipoxygenases.

PubMed ID: 24282679

DOI: 10.1016/j.redox.2013.11.001

PubMed ID: 27145229

Title: Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.

PubMed ID: 27145229

DOI: 10.1021/acs.biochem.5b01339

PubMed ID: 27435673

Title: Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.

PubMed ID: 27435673

DOI: 10.1074/jbc.m116.741454

PubMed ID: 32404334

Title: 15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5.

PubMed ID: 32404334

DOI: 10.1194/jlr.ra120000777

PubMed ID: 24497644

Title: The structure of human 15-lipoxygenase-2 with a substrate mimic.

PubMed ID: 24497644

DOI: 10.1074/jbc.m113.543777

Sequence Information:

  • Length: 676
  • Mass: 75857
  • Checksum: 4F641DF2F9D492C6
  • Sequence:
    • MAEFRVRVST GEAFGAGTWD KVSVSIVGTR GESPPLPLDN LGKEFTAGAE EDFQVTLPED 
VGRVLLLRVH KAPPVLPLLG PLAPDAWFCR WFQLTPPRGG HLLFPCYQWL EGAGTLVLQE 
GTAKVSWADH HPVLQQQRQE ELQARQEMYQ WKAYNPGWPH CLDEKTVEDL ELNIKYSTAK 
NANFYLQAGS AFAEMKIKGL LDRKGLWRSL NEMKRIFNFR RTPAAEHAFE HWQEDAFFAS 
QFLNGLNPVL IRRCHYLPKN FPVTDAMVAS VLGPGTSLQA ELEKGSLFLV DHGILSGIQT 
NVINGKPQFS AAPMTLLYQS PGCGPLLPLA IQLSQTPGPN SPIFLPTDDK WDWLLAKTWV 
RNAEFSFHEA LTHLLHSHLL PEVFTLATLR QLPHCHPLFK LLIPHTRYTL HINTLARELL 
IVPGQVVDRS TGIGIEGFSE LIQRNMKQLN YSLLCLPEDI RTRGVEDIPG YYYRDDGMQI 
WGAVERFVSE IIGIYYPSDE SVQDDRELQA WVREIFSKGF LNQESSGIPS SLETREALVQ 
YVTMVIFTCS AKHAAVSAGQ FDSCAWMPNL PPSMQLPPPT SKGLATCEGF IATLPPVNAT 
CDVILALWLL SKEPGDQRPL GTYPDEHFTE EAPRRSIATF QSRLAQISRG IQERNQGLVL 
PYTYLDPPLI ENSVSI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.