Genular: Defining Cellular Identity and Function

Details for: Ccl2

Gene ID: 24770

Symbol: Ccl2

Ensembl ID: ENSRNOG00000007159

Description: C-C motif chemokine ligand 2

Associated with

Animal organ regeneration
(GO:0031100)
Astrocyte cell migration
(GO:0043615)
Ccr2 chemokine receptor binding
(GO:0031727)
Ccr chemokine receptor binding
(GO:0048020)
Cellular response to atp
(GO:0071318)
Cellular response to dexamethasone stimulus
(GO:0071549)
Cellular response to estradiol stimulus
(GO:0071392)
Cellular response to fatty acid
(GO:0071398)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to glucose stimulus
(GO:0071333)
Cellular response to high density lipoprotein particle stimulus
(GO:0071403)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to interleukin-6
(GO:0071354)
Cellular response to lipopolysaccharide
(GO:0071222)
Cellular response to lipoprotein particle stimulus
(GO:0071402)
Cellular response to macrophage colony-stimulating factor stimulus
(GO:0036006)
Cellular response to platelet-derived growth factor stimulus
(GO:0036120)
Cellular response to retinoic acid
(GO:0071300)
Cellular response to tumor necrosis factor
(GO:0071356)
Cellular response to type ii interferon
(GO:0071346)
Cellular response to xenobiotic stimulus
(GO:0071466)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemokinesis
(GO:0042466)
Chronic inflammatory response
(GO:0002544)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Cytoskeleton organization
(GO:0007010)
Eosinophil chemotaxis
(GO:0048245)
Glial cell migration
(GO:0008347)
G protein-coupled receptor binding
(GO:0001664)
G protein-coupled receptor signaling pathway
(GO:0007186)
Helper t cell extravasation
(GO:0035684)
Heparin binding
(GO:0008201)
Inflammatory response
(GO:0006954)
Intracellular calcium ion homeostasis
(GO:0006874)
Leukocyte migration involved in inflammatory response
(GO:0002523)
Lymphocyte chemotaxis
(GO:0048247)
Macrophage chemotaxis
(GO:0048246)
Mammary gland involution
(GO:0060056)
Maternal process involved in female pregnancy
(GO:0060135)
Maternal process involved in parturition
(GO:0060137)
Monocyte chemotaxis
(GO:0002548)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of glial cell apoptotic process
(GO:0034351)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neutrophil chemotaxis
(GO:0030593)
Osteoclast differentiation
(GO:0030316)
Positive regulation of cell-cell adhesion
(GO:0022409)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of cellular extravasation
(GO:0002693)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of gtpase activity
(GO:0043547)
Positive regulation of leukocyte mediated cytotoxicity
(GO:0001912)
Positive regulation of leukocyte migration
(GO:0002687)
Positive regulation of macrophage chemotaxis
(GO:0010759)
Positive regulation of monocyte chemotaxis
(GO:0090026)
Positive regulation of nitric-oxide synthase biosynthetic process
(GO:0051770)
Positive regulation of synaptic transmission
(GO:0050806)
Positive regulation of synaptic transmission, glutamatergic
(GO:0051968)
Positive regulation of t cell activation
(GO:0050870)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Regulation of cell shape
(GO:0008360)
Regulation of vascular endothelial growth factor production
(GO:0010574)
Response to activity
(GO:0014823)
Response to amino acid
(GO:0043200)
Response to bacterium
(GO:0009617)
Response to ethanol
(GO:0045471)
Response to gamma radiation
(GO:0010332)
Response to glucocorticoid
(GO:0051384)
Response to hypoxia
(GO:0001666)
Response to isolation stress
(GO:0035900)
Response to lipopolysaccharide
(GO:0032496)
Response to mechanical stimulus
(GO:0009612)
Response to progesterone
(GO:0032570)
Response to tumor necrosis factor
(GO:0034612)
Response to vitamin b3
(GO:0033552)
Response to wounding
(GO:0009611)
Response to xenobiotic stimulus
(GO:0009410)
Sensory perception of pain
(GO:0019233)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Vascular endothelial growth factor receptor signaling pathway
(GO:0048010)

Other Information

Proteins

C-C motif chemokine 2

Genular Protein ID: 610838565

Symbol: CCL2_RAT

Name: C-C motif chemokine 2

UniProtKB Accession Codes:

P14844 Q549R5

Database IDs:

Citations:

PubMed ID: 2106664

Title: Analysis of the rat JE gene promoter identifies an AP-1 binding site essential for basal expression but not for TPA induction.

PubMed ID: 2106664

DOI: 10.1093/nar/18.1.23

PubMed ID: 1704226

Title: Molecular cloning of rat monocyte chemoattractant protein-1 (MCP-1) and its expression in rat spleen cells and tumor cell lines.

PubMed ID: 1704226

DOI: 10.1016/0006-291x(91)91445-i

PubMed ID: 23955712

Title: Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.

PubMed ID: 23955712

DOI: 10.1038/nm.3265

Sequence Information:

Length: 148
Mass: 16460
Checksum: 62D4C42BF4B11C9D
Sequence:

MQVSVTLLGL LFTVAACSIH VLSQPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP 
KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT 
HKSEANASTL FSTTTSSTSV EVTSMTEN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.