Genular: Defining Cellular Identity and Function

Details for: Sod2

Gene ID: 24787

Symbol: Sod2

Ensembl ID: ENSRNOG00000019048

Description: superoxide dismutase 2

Associated with

Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular response to chemical stress
(R-RNO-9711123)
Detoxification of reactive oxygen species
(R-RNO-3299685)
Mitochondrial biogenesis
(R-RNO-1592230)
Organelle biogenesis and maintenance
(R-RNO-1852241)
Transcriptional activation of mitochondrial biogenesis
(R-RNO-2151201)
Acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure
(GO:0003069)
Apoptotic mitochondrial changes
(GO:0008637)
Cellular response to ethanol
(GO:0071361)
Cellular response to oxidative stress
(GO:0034599)
Detection of oxygen
(GO:0003032)
Dna binding
(GO:0003677)
Enzyme binding
(GO:0019899)
Erythrophore differentiation
(GO:0048773)
Glutathione metabolic process
(GO:0006749)
Heart development
(GO:0007507)
Hemopoiesis
(GO:0030097)
Hydrogen peroxide biosynthetic process
(GO:0050665)
Hydrogen peroxide metabolic process
(GO:0042743)
Identical protein binding
(GO:0042802)
Intracellular oxygen homeostasis
(GO:0032364)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Intrinsic apoptotic signaling pathway in response to oxidative stress
(GO:0008631)
Liver development
(GO:0001889)
Locomotory behavior
(GO:0007626)
Manganese ion binding
(GO:0030145)
Mitochondrial matrix
(GO:0005759)
Mitochondrial nucleoid
(GO:0042645)
Mitochondrion
(GO:0005739)
Mitochondrion organization
(GO:0007005)
Multicellular organismal-level iron ion homeostasis
(GO:0060586)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of fat cell differentiation
(GO:0045599)
Negative regulation of fibroblast proliferation
(GO:0048147)
Negative regulation of membrane hyperpolarization
(GO:1902631)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
(GO:1902176)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Neuron development
(GO:0048666)
Oxidoreductase activity
(GO:0016491)
Oxygen binding
(GO:0019825)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of hydrogen peroxide biosynthetic process
(GO:0010729)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of vascular associated smooth muscle cell apoptotic process
(GO:1905461)
Positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
(GO:1905932)
Post-embryonic development
(GO:0009791)
Protein homotetramerization
(GO:0051289)
Regulation of blood pressure
(GO:0008217)
Regulation of mitochondrial membrane potential
(GO:0051881)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Release of cytochrome c from mitochondria
(GO:0001836)
Removal of superoxide radicals
(GO:0019430)
Respiratory electron transport chain
(GO:0022904)
Response to activity
(GO:0014823)
Response to axon injury
(GO:0048678)
Response to cadmium ion
(GO:0046686)
Response to electrical stimulus
(GO:0051602)
Response to gamma radiation
(GO:0010332)
Response to hydrogen peroxide
(GO:0042542)
Response to hyperoxia
(GO:0055093)
Response to hypoxia
(GO:0001666)
Response to immobilization stress
(GO:0035902)
Response to isolation stress
(GO:0035900)
Response to l-ascorbic acid
(GO:0033591)
Response to lipopolysaccharide
(GO:0032496)
Response to magnetism
(GO:0071000)
Response to manganese ion
(GO:0010042)
Response to nutrient levels
(GO:0031667)
Response to oxidative stress
(GO:0006979)
Response to reactive oxygen species
(GO:0000302)
Response to selenium ion
(GO:0010269)
Response to silicon dioxide
(GO:0034021)
Response to superoxide
(GO:0000303)
Response to xenobiotic stimulus
(GO:0009410)
Response to zinc ion
(GO:0010043)
Sensory perception of sound
(GO:0007605)
Superoxide anion generation
(GO:0042554)
Superoxide dismutase activity
(GO:0004784)
Superoxide metabolic process
(GO:0006801)
Vasodilation
(GO:0042311)

Other Information

Proteins

Superoxide dismutase [Mn], mitochondrial

Genular Protein ID: 3714579702

Symbol: SODM_RAT

Name: Superoxide dismutase [Mn], mitochondrial

UniProtKB Accession Codes:

P07895

Database IDs:

Citations:

PubMed ID: 3697077

Title: Nucleotide sequences of cDNAs coding for rat manganese-containing superoxide dismutase.

PubMed ID: 3697077

DOI: 10.1093/nar/15.23.10070

PubMed ID: 2001291

Title: Molecular structure of a functional rat gene for manganese-containing superoxide dismutase.

PubMed ID: 2001291

DOI: 10.1165/ajrcmb/4.3.278

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12791589

Title: Quantitative assessment of tyrosine nitration of manganese superoxide dismutase in angiotensin II-infused rat kidney.

PubMed ID: 12791589

DOI: 10.1152/ajpheart.00096.2003

PubMed ID: 16399855

Title: Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.

PubMed ID: 16399855

DOI: 10.1152/ajpheart.01293.2005

Sequence Information:

Length: 222
Mass: 24674
Checksum: 8CCC1E0E857B3138
Sequence:

MLCRAACSAG RRLGPAASTA GSRHKHSLPD LPYDYGALEP HINAQIMQLH HSKHHATYVN 
NLNVTEEKYH EALAKGDVTT QVALQPALKF NGGGHINHSI FWTNLSPKGG GEPKGELLEA 
IKRDFGSFEK FKEKLTAVSV GVQGSGWGWL GFNKEQGRLQ IAACSNQDPL QGTTGLIPLL 
GIDVWEHAYY LQYKNVRPDY LKAIWNVINW ENVSQRYIVC KK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sod2

Associated with

Other Information

Nucleotide sequences of cDNAs coding for rat manganese-containing superoxide dismutase. PubMed ID: 3697077

Molecular structure of a functional rat gene for manganese-containing superoxide dismutase. PubMed ID: 2001291

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334