Details for: Serpina3c

Gene ID: 24794

Symbol: Serpina3c

Ensembl ID: ENSRNOG00000010410

Description: serine (or cysteine) proteinase inhibitor, clade A, member 3C

Associated with

  • Extracellular space
    (GO:0005615)
  • Negative regulation of angiogenesis
    (GO:0016525)
  • Negative regulation of endopeptidase activity
    (GO:0010951)
  • Negative regulation of endothelial cell proliferation
    (GO:0001937)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Serine-type endopeptidase inhibitor activity
    (GO:0004867)

Other Information

Genular Protein ID: 1608977045

Symbol: SPA3K_RAT

Name: Serine protease inhibitor A3K

UniProtKB Accession Codes:

P05545 P14281 Q64254 Q6P6G8

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 CDD 1 CTD 1 EMBL 7 GO 2 Gene3D 2 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2440672

Title: Study of a growth hormone-regulated protein secreted by rat hepatocytes: cDNA cloning, anti-protease activity and regulation of its synthesis by various hormones.

PubMed ID: 2440672

DOI: 10.1002/j.1460-2075.1987.tb02358.x

PubMed ID: 3494016

Title: Growth hormone induces two mRNA species of the serine protease inhibitor gene family in rat liver.

PubMed ID: 3494016

DOI: 10.1016/s0021-9258(18)61345-6

PubMed ID: 1694763

Title: Molecular characterization of three rat liver serine-protease inhibitors affected by inflammation and hypophysectomy. Protein and mRNA analysis and cDNA cloning.

PubMed ID: 1694763

DOI: 10.1111/j.1432-1033.1990.tb15587.x

PubMed ID: 2258058

Title: Primary structure and assignment to chromosome 6 of three related rat genes encoding liver serine protease inhibitors.

PubMed ID: 2258058

DOI: 10.1016/0378-1119(90)90398-b

PubMed ID: 1864837

Title: Molecular cloning and characterization of rat contrapsin-like protease inhibitor and related proteins.

PubMed ID: 1864837

PubMed ID: 1874745

Title: Molecular cloning and analysis of the rat kallikrein-binding protein gene.

PubMed ID: 1874745

DOI: 10.1016/s0021-9258(18)98511-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2398056

Title: Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats.

PubMed ID: 2398056

DOI: 10.1016/s0021-9258(17)46236-3

PubMed ID: 15638460

Title: Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus.

PubMed ID: 15638460

DOI: 10.1007/s00239-004-2640-9

Sequence Information:

  • Length: 416
  • Mass: 46562
  • Checksum: 6072BAE56BFF91B1
  • Sequence:
    • MAFIAALGLL MAGICPAVLC DGILGRDTLP HEDQGKGRQL HSLTLASINT DFTLSLYKKL 
ALRNPDKNVV FSPLSISAAL AILSLGAKDS TMEEILEVLK FNLTEITEEE IHQGFGHLLQ 
RLSQPEDQAE INTGSALFID KEQPILSEFQ EKTRALYQAE AFVADFKQCN EAKKFINDYV 
SNQTQGKIAE LFSELDERTS MVLVNYLLFK GKWKVPFNPN DTFESEFYLD EKRSVKVPMM 
KIKDLTTPYI RDEELSCSVL ELKYTGNASA LFILPDQGKM QQVESSLQPE TLKKWKDSLR 
PRIISELRMP KFSISTDYNL EEVLPELGIR KIFSQQADLS RITGTKNLHV SQVVHKAVLD 
VDETGTEGAA ATAVTAALKS LPQTIPLLNF NRPFMLVITD NNGQSVFFMG KVTNPM

Genular Protein ID: 4027805928

Symbol: A0A0G2JSK1_RAT

Name: N/A

UniProtKB Accession Codes:

A0A0G2JSK1

Database IDs:

AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 1 Proteomes 2 RGD 2 RefSeq 2 RuleBase 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 416
  • Mass: 46477
  • Checksum: D361336B46668CB8
  • Sequence:
    • MAFIAALGLL MAGICPAVLC DGILGRDTLP HEDQGKGRQL HSLTLASINT DFTLSLYKKL 
ALRNPDKNVV FSPLSISAAL AILSLGAKDS TMEEILEGLK FNLTEITEEE IHQGFGHLLQ 
RLSQPEDQAE INTGSALFID KEQPILSEFQ EKTRALYQAE AFVADFKQCN EAKKFINDYV 
SNQTQGKIAE LFSDLDERTS MVLVNYLLFK GKWKVPFNPN DTFESEFYLD EKRSVKVPMM 
KIKDLTTPYV RDEELSCSVL ELKYTGNASA LFILPDQGKM QQVESSLQPE TLKKWKDSLR 
PRIISELRMP KFSISTDYNL EEVLPELGIR KIFSQQADLS RITGTKNLHV SQVVHKAVLD 
VDETGTEGAA ATAVTAALKS LPQTVPLLNF NRPFMLVITD NNGQSVFFMG KVTNPM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.