Vamp2 | ENSRNOG00000006989 | NCBI 24803

Details for: Vamp2

Gene ID: 24803

Symbol: Vamp2

Ensembl ID: ENSRNOG00000006989

Description: vesicle-associated membrane protein 2

Associated with

Acetylcholine neurotransmitter release cycle
(R-RNO-264642)
Cargo recognition for clathrin-mediated endocytosis
(R-RNO-8856825)
Clathrin-mediated endocytosis
(R-RNO-8856828)
Cytokine signaling in immune system
(R-RNO-1280215)
Dopamine neurotransmitter release cycle
(R-RNO-212676)
Gaba synthesis, release, reuptake and degradation
(R-RNO-888590)
Glutamate neurotransmitter release cycle
(R-RNO-210500)
Golgi associated vesicle biogenesis
(R-RNO-432722)
Immune system
(R-RNO-168256)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
(R-RNO-9609523)
Lysosome vesicle biogenesis
(R-RNO-432720)
Membrane trafficking
(R-RNO-199991)
Neuronal system
(R-RNO-112316)
Neurotransmitter release cycle
(R-RNO-112310)
Norepinephrine neurotransmitter release cycle
(R-RNO-181430)
Other interleukin signaling
(R-RNO-449836)
Protein localization
(R-RNO-9609507)
Serotonin neurotransmitter release cycle
(R-RNO-181429)
Signaling by interleukins
(R-RNO-449147)
Trans-golgi network vesicle budding
(R-RNO-199992)
Transmission across chemical synapses
(R-RNO-112315)
Calcium-dependent protein binding
(GO:0048306)
Calcium-ion regulated exocytosis
(GO:0017156)
Calmodulin binding
(GO:0005516)
Cellular response to insulin stimulus
(GO:0032869)
Clathrin-coated vesicle
(GO:0030136)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytoplasmic vesicle membrane
(GO:0030659)
Eosinophil degranulation
(GO:0043308)
Establishment of localization in cell
(GO:0051649)
Exocytic insertion of neurotransmitter receptor to postsynaptic membrane
(GO:0098967)
Golgi to plasma membrane protein transport
(GO:0043001)
Hormone secretion
(GO:0046879)
Identical protein binding
(GO:0042802)
Lipid binding
(GO:0008289)
Long-term synaptic potentiation
(GO:0060291)
Membrane
(GO:0016020)
Membrane fusion
(GO:0061025)
Molecular adaptor activity
(GO:0060090)
Mucus secretion
(GO:0070254)
Myosin binding
(GO:0017022)
Natural killer cell degranulation
(GO:0043320)
Neuron projection terminus
(GO:0044306)
Neutrophil degranulation
(GO:0043312)
Perinuclear region of cytoplasm
(GO:0048471)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Positive regulation of intracellular protein transport
(GO:0090316)
Protein-containing complex assembly
(GO:0065003)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulated exocytosis
(GO:0045055)
Regulation of exocytosis
(GO:0017157)
Regulation of histamine secretion by mast cell
(GO:1903593)
Regulation of synaptic vesicle recycling
(GO:1903421)
Regulation of vesicle-mediated transport
(GO:0060627)
Response to glucose
(GO:0009749)
Secretory granule
(GO:0030141)
Secretory granule membrane
(GO:0030667)
Snap receptor activity
(GO:0005484)
Snare binding
(GO:0000149)
Snare complex
(GO:0031201)
Snare complex assembly
(GO:0035493)
Storage vacuole
(GO:0000322)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle docking
(GO:0016081)
Synaptic vesicle endocytosis
(GO:0048488)
Synaptic vesicle exocytosis
(GO:0016079)
Synaptic vesicle membrane
(GO:0030672)
Syntaxin-1 binding
(GO:0017075)
Syntaxin binding
(GO:0019905)
Terminal bouton
(GO:0043195)
Trans-golgi network
(GO:0005802)
Transmembrane transporter binding
(GO:0044325)
Vesicle
(GO:0031982)
Vesicle-mediated transport
(GO:0016192)
Vesicle fusion
(GO:0006906)
Voltage-gated potassium channel complex
(GO:0008076)
Zymogen granule membrane
(GO:0042589)

Other Information

Proteins

Vesicle-associated membrane protein 2
A0A8I5ZNB8_RAT

Genular Protein ID: 1027713913

Symbol: VAMP2_RAT

Name: Vesicle-associated membrane protein 2

UniProtKB Accession Codes:

P63045 Q64357

Database IDs:

Citations:

PubMed ID: 2472388

Title: Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous system.

PubMed ID: 2472388

DOI: 10.1016/s0021-9258(18)60426-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 28770820

Title: Identification and characterization of a novel botulinum neurotoxin.

PubMed ID: 28770820

DOI: 10.1038/ncomms14130

PubMed ID: 1331807

Title: Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin.

PubMed ID: 1331807

DOI: 10.1038/359832a0

PubMed ID: 8505288

Title: Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin.

PubMed ID: 8505288

DOI: 10.1016/s0021-9258(19)50230-7

PubMed ID: 7910017

Title: Botulinum neurotoxin type G proteolyses the Ala81-Ala82 bond of rat synaptobrevin 2.

PubMed ID: 7910017

DOI: 10.1006/bbrc.1994.1526

PubMed ID: 8175689

Title: Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.

PubMed ID: 8175689

DOI: 10.1016/s0021-9258(18)99941-2

PubMed ID: 19690160

Title: Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating.

PubMed ID: 19690160

DOI: 10.1074/jbc.m109.028761

PubMed ID: 19196426

Title: Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin.

PubMed ID: 19196426

DOI: 10.1111/j.1471-4159.2008.05849.x

PubMed ID: 9759724

Title: Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution.

PubMed ID: 9759724

DOI: 10.1038/26412

PubMed ID: 11832227

Title: Three-dimensional structure of the complexin/SNARE complex.

PubMed ID: 11832227

DOI: 10.1016/s0896-6273(02)00583-4

PubMed ID: 12496247

Title: High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex.

PubMed ID: 12496247

DOI: 10.1074/jbc.m211889200

Sequence Information:

Length: 116
Mass: 12691
Checksum: 4A0D0D56B5409D0A
Sequence:

MSATAATVPP AAPAGEGGPP APPPNLTSNR RLQQTQAQVD EVVDIMRVNV DKVLERDQKL 
SELDDRADAL QAGASQFETS AAKLKRKYWW KNLKMMIILG VICAIILIII IVYFST

Genular Protein ID: 634780943

Symbol: A0A8I5ZNB8_RAT

Name: N/A

UniProtKB Accession Codes:

A0A8I5ZNB8

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

Length: 135
Mass: 14581
Checksum: F37D14AB1BDAB1F6
Sequence:

MSATAATVPP AAPAGEGGPP APPPNLTSNR RLQQTQAQVD EVVDIMRVNV DKVLERDQKL 
SELDDRADAL QAGASQFETS AAKLKRKYWW KNLKMMIILG VICAIILIII IGEWSRSGQG 
PFPGEVEGFP VESGL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vamp2

Associated with

Other Information

Two vesicle-associated membrane protein genes are differentially expressed in the rat central nervous system. PubMed ID: 2472388

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification and characterization of a novel botulinum neurotoxin. PubMed ID: 28770820

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. PubMed ID: 1331807

Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin. PubMed ID: 8505288

Botulinum neurotoxin type G proteolyses the Ala81-Ala82 bond of rat synaptobrevin 2. PubMed ID: 7910017

Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin. PubMed ID: 8175689

Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating. PubMed ID: 19690160

Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin. PubMed ID: 19196426

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. PubMed ID: 9759724

Three-dimensional structure of the complexin/SNARE complex. PubMed ID: 11832227

High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex. PubMed ID: 12496247

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822