Genular: Defining Cellular Identity and Function

Details for: Tbxa2r

Gene ID: 24816

Symbol: Tbxa2r

Ensembl ID: ENSRNOG00000020585

Description: thromboxane A2 receptor

Associated with

Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
Eicosanoid ligand-binding receptors
(R-RNO-391903)
G alpha (12/13) signalling events
(R-RNO-416482)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Hemostasis
(R-RNO-109582)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Prostanoid ligand receptors
(R-RNO-391908)
Signal amplification
(R-RNO-392518)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Thromboxane signalling through tp receptor
(R-RNO-428930)
Acrosomal vesicle
(GO:0001669)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Cellular response to lipopolysaccharide
(GO:0071222)
Inflammatory response
(GO:0006954)
Negative regulation of cell migration involved in sprouting angiogenesis
(GO:0090051)
Nuclear speck
(GO:0016607)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of blood coagulation
(GO:0030194)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of smooth muscle contraction
(GO:0045987)
Positive regulation of vasoconstriction
(GO:0045907)
Protein binding
(GO:0005515)
Regulation of vasoconstriction
(GO:0019229)
Response to ethanol
(GO:0045471)
Response to lipopolysaccharide
(GO:0032496)
Response to nutrient
(GO:0007584)
Response to testosterone
(GO:0033574)
Response to xenobiotic stimulus
(GO:0009410)
Smooth muscle contraction
(GO:0006939)
Thromboxane receptor activity
(GO:0004960)

Other Information

Proteins

Thromboxane A2 receptor

Genular Protein ID: 2687535058

Symbol: TA2R_RAT

Name: Thromboxane A2 receptor

UniProtKB Accession Codes:

P34978

Database IDs:

Citations:

PubMed ID: 7635958

Title: Rat kidney thromboxane receptor: molecular cloning, signal transduction, and intrarenal expression localization.

PubMed ID: 7635958

DOI: 10.1172/jci118108

PubMed ID: 7696353

Title: cDNA cloning of a thromboxane A2 receptor from rat astrocytes.

PubMed ID: 7696353

DOI: 10.1016/0167-4889(94)00225-4

PubMed ID: 8936585

Title: Characterization of a rat kidney thromboxane A2 receptor: high affinity for the agonist ligand I-BOP.

PubMed ID: 8936585

DOI: 10.1016/s0090-6980(96)00091-3

Sequence Information:

Length: 341
Mass: 36928
Checksum: E85843FE54C1CD94
Sequence:

MWLNSTSLGA CFRPVNITLQ ERRAIASPWF AASFCALGLG SNLLALSVLA GARPGAGPRS 
SFLALLCGLV LTDFLGLLVT GAVVASQHAA LLDWRATDPG CRLCHFMGAA MVFFGLCPLL 
LGAAMAAERF VGITRPFSRP AATSRRAWAT VGLVWVGAGT LGLLPLLGLG RYSVQYPGSW 
CFLTLGAERG DVAFGLMFAL LGSVSVGLSL LLNTVSVATL CRVYHAREAT QRPRDCEVEM 
MVQLVGIMVV ATVCWMPLLV FILQTLLQTL PVMSPSGQLL RTTERQLLIY LRVATWNQIL 
DPWVYILFRR SVLRRLHPRF TSQLQAVSLH SPPTQAMLSG P

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.