Details for: Spink1

Gene ID: 24833

Symbol: Spink1

Ensembl ID: ENSRNOG00000068869

Description: serine peptidase inhibitor, Kazal type 1

Associated with

  • Cellular response to peptide hormone stimulus
    (GO:0071375)
  • Extracellular space
    (GO:0005615)
  • Negative regulation of calcium ion import
    (GO:0090281)
  • Negative regulation of nitric oxide mediated signal transduction
    (GO:0010751)
  • Negative regulation of peptidyl-tyrosine phosphorylation
    (GO:0050732)
  • Nitric oxide mediated signal transduction
    (GO:0007263)
  • Peptidase inhibitor activity
    (GO:0030414)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of epithelial cell proliferation
    (GO:0050679)
  • Positive regulation of pancreatic juice secretion
    (GO:0090187)
  • Positive regulation of peptide hormone secretion
    (GO:0090277)
  • Regulation of acrosome reaction
    (GO:0060046)
  • Regulation of store-operated calcium entry
    (GO:2001256)
  • Response to ethanol
    (GO:0045471)
  • Response to nutrient levels
    (GO:0031667)
  • Serine-type endopeptidase inhibitor activity
    (GO:0004867)
  • Sperm capacitation
    (GO:0048240)

Other Information

Genular Protein ID: 3805815985

Symbol: ISK1_RAT

Name: N/A

UniProtKB Accession Codes:

P09655 P13072

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 CDD 1 CTD 1 EMBL 6 Ensembl 4 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 2 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2602119

Title: Complementary nucleotide sequence for monitor peptide, a novel cholecystokinin-releasing peptide in the rat.

PubMed ID: 2602119

DOI: 10.1093/nar/17.23.10111

PubMed ID: 2293709

Title: Rapid and selective cloning of monitor peptide, a novel cholecystokinin-releasing peptide, using minimal amino acid sequence and the polymerase chain reaction.

PubMed ID: 2293709

DOI: 10.1097/00006676-199001000-00001

PubMed ID: 2751646

Title: On the cDNA's for two types of rat pancreatic secretory trypsin inhibitor.

PubMed ID: 2751646

DOI: 10.1016/0006-291x(89)91975-x

PubMed ID: 2065678

Title: Effect of a high-protein diet on the gene expression of a trypsin-sensitive, cholecystokinin-releasing peptide (monitor peptide) in the pancreas.

PubMed ID: 2065678

DOI: 10.1111/j.1432-1033.1991.tb16116.x

PubMed ID: 1390891

Title: Molecular cloning and characterization of genes encoding rat pancreatic cholecystokinin (CCK)-releasing peptide (monitor peptide) and pancreatic secretory trypsin inhibitor (PSTI).

PubMed ID: 1390891

DOI: 10.1016/0167-4781(92)90012-o

PubMed ID: 3202973

Title: Purification, characterization and amino-acid sequencing of two pancreatic secretory trypsin inhibitors in rat pancreatic juice.

PubMed ID: 3202973

PubMed ID: 3597401

Title: Purification and sequencing of a trypsin-sensitive cholecystokinin-releasing peptide from rat pancreatic juice. Its homology with pancreatic secretory trypsin inhibitor.

PubMed ID: 3597401

DOI: 10.1016/s0021-9258(18)48028-3

Sequence Information:

  • Length: 79
  • Mass: 8528
  • Checksum: 5816D55DF7B57874
  • Sequence:
    • MKVAIIFLLS ALALLSLAGN PPAEVNGKTP NCPKQIMGCP RIYDPVCGTN GITYPSECSL 
CFENRKFGTS IHIQRRGTC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.