Details for: Tph1

Gene ID: 24848

Symbol: Tph1

Ensembl ID: ENSRNOG00000011672

Description: tryptophan hydroxylase 1

Associated with

Other Information

Genular Protein ID: 3850878984

Symbol: TPH1_RAT

Name: Tryptophan 5-hydroxylase 1

UniProtKB Accession Codes:

P09810

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BindingDB 1 CDD 2 CTD 1 ChEBI 14 ChEMBL 1 EC 1 EMBL 2 Ensembl 4 GO 14 Gene3D 1 GeneTree 1 HOGENOM 1 InParanoid 1 InterPro 10 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 2 Rhea 1 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 2 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 3379411

Title: Sequence of two mRNAs encoding active rat tryptophan hydroxylase.

PubMed ID: 3379411

DOI: 10.1111/j.1471-4159.1988.tb04871.x

PubMed ID: 1645430

Title: Molecular cloning and characterization of cDNA encoding tryptophan hydroxylase from rat central serotonergic neurons.

PubMed ID: 1645430

DOI: 10.1016/0169-328x(91)90073-7

PubMed ID: 2875901

Title: Isolation of a rat pineal gland cDNA clone homologous to tyrosine and phenylalanine hydroxylases.

PubMed ID: 2875901

DOI: 10.1016/0014-5793(86)81337-0

PubMed ID: 12354109

Title: Proteasome-driven turnover of tryptophan hydroxylase is triggered by phosphorylation in RBL2H3 cells, a serotonin producing mast cell line.

PubMed ID: 12354109

DOI: 10.1046/j.1432-1033.2002.03188.x

Sequence Information:

  • Length: 444
  • Mass: 51068
  • Checksum: C3CF5245727CC825
  • Sequence:
    • MIEDNKENKD HSSERGRVTL IFSLKNEVGG LIKALKIFQE NHVNLLHIES RKSKRRNSEF 
EIFVDCDINR EQLNDIFPLL KSHTTVLSVD SPDQLPEKED VMETVPWFPK KISDLDFCAN 
RVLLYGSELD ADHPGFKDNV YRRRRKYFAE LAMNYKHGDP IPKIEFTEEE IKTWGTIFRE 
LNKLYPTHAC REYLRNLPLL SKYCGYREDN VPQLEDVSNF LKERTGFSIR PVAGYLSPRD 
FLSGLAFRVF HCTQYVRHSS DPLYTPEPDT CHELLGHVPL LAEPSFAQFS QEIGLASLGA 
SEETVQKLAT CYFFTVEFGL CKQDGQLRVF GAGLLSSISE LRHALSGHAK VKPFDPKVAC 
KQECLITSFQ DVYFVSESFE DAKEKMREFA KTVKRPFGVK YNPYTQSIQV LRDSKSITSA 
MNELRHDLDV VNDALARVSR WPSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.