Genular: Defining Cellular Identity and Function

Details for: Vdr

Gene ID: 24873

Symbol: Vdr

Ensembl ID: ENSRNOG00000054420

Description: vitamin D receptor

Associated with

Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of proteins
(R-RNO-392499)
Metabolism of steroids
(R-RNO-8957322)
Nuclear receptor transcription pathway
(R-RNO-383280)
Post-translational protein modification
(R-RNO-597592)
Rna polymerase ii transcription
(R-RNO-73857)
Sumo e3 ligases sumoylate target proteins
(R-RNO-3108232)
Sumoylation
(R-RNO-2990846)
Sumoylation of intracellular receptors
(R-RNO-4090294)
Vitamin d (calciferol) metabolism
(R-RNO-196791)
Animal organ morphogenesis
(GO:0009887)
Apoptotic process involved in mammary gland involution
(GO:0060057)
Apoptotic signaling pathway
(GO:0097190)
Bile acid signaling pathway
(GO:0038183)
Calcitriol binding
(GO:1902098)
Calcium ion transport
(GO:0006816)
Caveola
(GO:0005901)
Cell differentiation
(GO:0030154)
Cell morphogenesis
(GO:0000902)
Cellular response to amyloid-beta
(GO:1904646)
Cellular response to vitamin d
(GO:0071305)
Cytosol
(GO:0005829)
Decidualization
(GO:0046697)
Dense fibrillar component
(GO:0001651)
Dna-binding transcription factor activity
(GO:0003700)
Dna binding
(GO:0003677)
Euchromatin
(GO:0000791)
Heart development
(GO:0007507)
Heterochromatin
(GO:0000792)
Intestinal absorption
(GO:0050892)
Intracellular calcium ion homeostasis
(GO:0006874)
Lactation
(GO:0007595)
Lithocholic acid binding
(GO:1902121)
Lithocholic acid receptor activity
(GO:0038186)
Mammary gland branching involved in pregnancy
(GO:0060745)
Mrna transcription by rna polymerase ii
(GO:0042789)
Multicellular organism development
(GO:0007275)
Negative regulation of bone trabecula formation
(GO:1900155)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of keratinocyte proliferation
(GO:0010839)
Negative regulation of ossification
(GO:0030279)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear matrix
(GO:0016363)
Nuclear receptor activity
(GO:0004879)
Nuclear retinoid x receptor binding
(GO:0046965)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphate ion transmembrane transport
(GO:0035435)
Positive regulation of apoptotic process involved in mammary gland involution
(GO:0060058)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of keratinocyte differentiation
(GO:0045618)
Positive regulation of parathyroid hormone secretion
(GO:2000830)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of vitamin d receptor signaling pathway
(GO:0070564)
Protein binding
(GO:0005515)
Receptor complex
(GO:0043235)
Regulation of calcium ion transport
(GO:0051924)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to aldosterone
(GO:1904044)
Response to bile acid
(GO:1903412)
Response to calcium ion
(GO:0051592)
Response to estradiol
(GO:0032355)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific dna binding
(GO:0043565)
Skeletal system development
(GO:0001501)
T-tubule
(GO:0030315)
Vitamin d binding
(GO:0005499)
Vitamin d receptor signaling pathway
(GO:0070561)
Vitamin d response element binding
(GO:0070644)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Vitamin D3 receptor

Genular Protein ID: 503140653

Symbol: VDR_RAT

Name: Vitamin D3 receptor

UniProtKB Accession Codes:

P13053

Database IDs:

Citations:

PubMed ID: 2849110

Title: Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor.

PubMed ID: 2849110

DOI: 10.1073/pnas.85.24.9499

PubMed ID: 2829212

Title: Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.

PubMed ID: 2829212

DOI: 10.1073/pnas.85.4.1005

PubMed ID: 10866662

Title: A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP.

PubMed ID: 10866662

DOI: 10.1128/mcb.20.14.5048-5063.2000

PubMed ID: 15065852

Title: Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.

PubMed ID: 15065852

DOI: 10.1021/bi036056y

PubMed ID: 17227670

Title: New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations.

PubMed ID: 17227670

DOI: 10.1016/j.abb.2006.11.029

Sequence Information:

Length: 423
Mass: 47814
Checksum: 1A0E519A9DCCE990
Sequence:

MEATAASTSL PDPGDFDRNV PRICGVCGDR ATGFHFNAMT CEGCKGFFRR SMKRKALFTC 
PFNGDCRITK DNRRHCQACR LKRCVDIGMM KEFILTDEEV QRKREMIMKR KEEEALKDSL 
RPKLSEEQQH IIAILLDAHH KTYDPTYADF RDFRPPVRMD GSTGSYSPRP TLSFSGNSSS 
SSSDLYTTSL DMMEPSGFSN LDLNGEDSDD PSVTLDLSPL SMLPHLADLV SYSIQKVIGF 
AKMIPGFRDL TSDDQIVLLK SSAIEVIMLR SNQSFTMDDM SWDCGSQDYK YDVTDVSKAG 
HTLELIEPLI KFQVGLKKLN LHEEEHVLLM AICIVSPDRP GVQDAKLVEA IQDRLSNTLQ 
TYIRCRHPPP GSHQLYAKMI QKLADLRSLN EEHSKQYRSL SFQPENSMKL TPLVLEVFGN 
EIS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vdr

Associated with

Other Information

Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor. PubMed ID: 2849110

Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA. PubMed ID: 2829212

A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP. PubMed ID: 10866662