Genular: Defining Cellular Identity and Function

Details for: Tbxas1

Gene ID: 24886

Symbol: Tbxas1

Ensembl ID: ENSRNOG00000007918

Description: thromboxane A synthase 1

Associated with

Arachidonic acid metabolism
(R-RNO-2142753)
Biological oxidations
(R-RNO-211859)
Cytochrome p450 - arranged by substrate type
(R-RNO-211897)
Eicosanoids
(R-RNO-211979)
Fatty acid metabolism
(R-RNO-8978868)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Phase i - functionalization of compounds
(R-RNO-211945)
Synthesis of prostaglandins (pg) and thromboxanes (tx)
(R-RNO-2162123)
12-hydroxyheptadecatrienoic acid synthase activity
(GO:0036134)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Heme binding
(GO:0020037)
Hydroperoxy icosatetraenoate dehydratase activity
(GO:0106256)
Icosanoid metabolic process
(GO:0006690)
Intracellular chloride ion homeostasis
(GO:0030644)
Iron ion binding
(GO:0005506)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Positive regulation of vasoconstriction
(GO:0045907)
Prostaglandin biosynthetic process
(GO:0001516)
Response to ethanol
(GO:0045471)
Response to fatty acid
(GO:0070542)
Thromboxane-a synthase activity
(GO:0004796)

Other Information

Proteins

Thromboxane-A synthase

Genular Protein ID: 815119484

Symbol: THAS_RAT

Name: Thromboxane-A synthase

UniProtKB Accession Codes:

P49430

Database IDs:

Citations:

PubMed ID: 8131852

Title: Abundant expression of thromboxane synthase in rat macrophages.

PubMed ID: 8131852

DOI: 10.1016/0014-5793(94)80146-0

PubMed ID: 9261862

Title: Rat kidney thromboxane synthase: cDNA cloning and gene expression regulation in hydronephrotic kidney.

PubMed ID: 9261862

DOI: 10.1016/s0090-6980(97)00059-2

Sequence Information:

Length: 533
Mass: 59974
Checksum: 6661BC5378D4E8C9
Sequence:

MEVLGLLKFE VSGTVVTVTL SVVLLALLKW YSTSAFSRLR KLGIRHPEPS PFVGNLMFFR 
QGFWESHLEL RERYGPLCGY YLGRRMYIVI SDPDMIKEVL VENFSNFSNR MASGLEPKLI 
ADSVLMLRDR RWEEVRGALM SAFSPEKLNE MTPLISQACE LLLSHLKHSA ASGDAFDIQR 
CYCCFTTNVV ASVAFGIEVN SQDAPEDPFV QHCQRVFAFS TPRPLLALIL SFPSIMVPLA 
RILPNKNRDE LNGFFNTLIR NVIALRDKQT AEERRGDFLQ MVLDAQRSMS SVGVEAFDMV 
TEALSSAECM GDPPQRCHPT STAKPLTVDE IAGQAFLFLI AGHEITTNTL SFITYLLATH 
PECQERLLKE VDLFMEKHPA PEYCNLQEGL PYLDMVVAET LRMYPPAFRF TREAAQDCEV 
LGQHIPAGSV LEIAVGALHH DPEHWPNPET FDPERFTAEA RLQQKPFTYL PFGAGPRSCL 
GVRLGLLVVK LTLLQVLHKF RFEACPETQV PLQLESKSAL CPKNGVYVKI VSR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.