Genular: Defining Cellular Identity and Function

Details for: Bax

Gene ID: 24887

Symbol: Bax

Ensembl ID: ENSRNOG00000020876

Description: BCL2 associated X, apoptosis regulator

Associated with

Activation, translocation and oligomerization of bax
(R-RNO-114294)
Apoptosis
(R-RNO-109581)
Apoptotic factor-mediated response
(R-RNO-111471)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Intrinsic pathway for apoptosis
(R-RNO-109606)
Programmed cell death
(R-RNO-5357801)
Pyroptosis
(R-RNO-5620971)
Regulated necrosis
(R-RNO-5218859)
Release of apoptotic factors from the mitochondria
(R-RNO-111457)
Rna polymerase ii transcription
(R-RNO-73857)
Tp53 regulates transcription of cell cycle genes
(R-RNO-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-RNO-6804114)
Transcriptional regulation by tp53
(R-RNO-3700989)
Apoptotic mitochondrial changes
(GO:0008637)
Apoptotic process
(GO:0006915)
B cell apoptotic process
(GO:0001783)
B cell homeostasis
(GO:0001782)
B cell homeostatic proliferation
(GO:0002358)
B cell negative selection
(GO:0002352)
Bh3 domain binding
(GO:0051434)
Bh domain binding
(GO:0051400)
Blood vessel remodeling
(GO:0001974)
Cell population proliferation
(GO:0008283)
Cellular respiration
(GO:0045333)
Cellular response to uv
(GO:0034644)
Cerebral cortex development
(GO:0021987)
Channel activity
(GO:0015267)
Development of secondary sexual characteristics
(GO:0045136)
Dna damage response
(GO:0006974)
Ectopic germ cell programmed cell death
(GO:0035234)
Establishment or maintenance of transmembrane electrochemical gradient
(GO:0010248)
Extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)
Fertilization
(GO:0009566)
Germ cell development
(GO:0007281)
Glial cell apoptotic process
(GO:0034349)
Glycosphingolipid metabolic process
(GO:0006687)
Heat shock protein binding
(GO:0031072)
Hsp70 protein binding
(GO:0030544)
Hypothalamus development
(GO:0021854)
Identical protein binding
(GO:0042802)
Inner mitochondrial membrane organization
(GO:0007007)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Kidney development
(GO:0001822)
Leukocyte homeostasis
(GO:0001776)
Limb morphogenesis
(GO:0035108)
Lipid binding
(GO:0008289)
Male gonad development
(GO:0008584)
Mitochondrial fragmentation involved in apoptotic process
(GO:0043653)
Mitochondrial fusion
(GO:0008053)
Mitochondrion organization
(GO:0007005)
Myeloid cell homeostasis
(GO:0002262)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of endoplasmic reticulum calcium ion concentration
(GO:0032471)
Negative regulation of mitochondrial membrane potential
(GO:0010917)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of peptidyl-serine phosphorylation
(GO:0033137)
Nervous system development
(GO:0007399)
Neuron migration
(GO:0001764)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Outer mitochondrial membrane organization
(GO:0007008)
Ovarian follicle development
(GO:0001541)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of b cell apoptotic process
(GO:0002904)
Positive regulation of calcium ion transport into cytosol
(GO:0010524)
Positive regulation of developmental pigmentation
(GO:0048087)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of protein-containing complex assembly
(GO:0031334)
Post-embryonic development
(GO:0009791)
Protein-containing complex binding
(GO:0044877)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of apoptotic process
(GO:0042981)
Regulation of mammary gland epithelial cell proliferation
(GO:0033599)
Regulation of neuron apoptotic process
(GO:0043523)
Regulation of nitrogen utilization
(GO:0006808)
Release of cytochrome c from mitochondria
(GO:0001836)
Release of matrix enzymes from mitochondria
(GO:0032976)
Response to cocaine
(GO:0042220)
Response to copper ion
(GO:0046688)
Response to gamma radiation
(GO:0010332)
Response to hypoxia
(GO:0001666)
Response to ionizing radiation
(GO:0010212)
Response to ischemia
(GO:0002931)
Response to salt stress
(GO:0009651)
Response to toxic substance
(GO:0009636)
Response to wounding
(GO:0009611)
Response to xenobiotic stimulus
(GO:0009410)
Retinal cell programmed cell death
(GO:0046666)
Sex differentiation
(GO:0007548)
Spermatogenesis
(GO:0007283)
T cell homeostatic proliferation
(GO:0001777)

Other Information

Proteins

Q9JKL3_RAT
A6JB34_RAT

Genular Protein ID: 4023196086

Symbol: Q9JKL3_RAT

Name: N/A

UniProtKB Accession Codes:

Q9JKL3

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 173
Mass: 19661
Checksum: F19A45BCF642C34F
Sequence:

MKTGAFLLQG FIQDRAERMA GETPELTLEQ PPQDASTKKL SECLRRIGDE LDNNMELQRM 
IADVDTDSPR EVFFRVAADM FADGNFNWGR VVALFYFASK LVLKALCTKV PELIRTIMGW 
TLDFLRERLL VWIQDQGGWD GLLSYFGTPT WQTVTIFVAG VLTASLTIWK KMG

Genular Protein ID: 1259881479

Symbol: A6JB34_RAT

Name: N/A

UniProtKB Accession Codes:

A6JB34

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 192
Mass: 21445
Checksum: 55935671C6F46478
Sequence:

MDGSGDHLGG GGPTSSEQIM KTGAFLLQGF IQDRAERMAG ETPELTLEQP PQDASTKKLS 
ECLRRIGDEL DNNMELQRMI ADVDTDSPRE VFFRVAADMF ADGNFNWGRV VALFYFASKL 
VLKALCTKVP ELIRTIMGWT LDFLRERLLV WIQDQGGWDG LLSYFGTPTW QTVTIFVAGV 
LTASLTIWKK MG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bax

Associated with

Other Information

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Database document:

PubMed ID: 15632090

PubMed ID: 15632090